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Trophic factor for dopamine neurons. De plus, nous expédions CDNF Anticorps (84) et CDNF Protéines (19) et beaucoup plus de produits pour cette protéine.
Showing 9 out of 30 products:
Rat (Rattus) CDNF Kit ELISA pour Sandwich ELISA - ABIN436170
Nadella, Voutilainen, Saarma, Gonzalez-Barrios, Leon-Chavez, Dueñas Jiménez, Dueñas Jiménez, Escobedo, Martinez-Fong: Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigra. dans Journal of neuroinflammation 2014
Show all 2 Pubmed References
The results showed that AAV8-CDNF administration significantly improved the motor function and increased the tyrosine hydroxylase (TH (Montrer TH Kits ELISA)) levels in Parkinson's disease rats with mild lesions (2 weeks post lesion), but it had limited therapeutic effects in rats with severe lesions (5 weeks post lesion).
Results suggest that CDNF treatment selectively enhances long-term memory consolidation
showed that CDNF was able to protect dopaminergic neurons against injury caused by alpha-synuclein oligomers. This advises its use against physiological damages caused by alpha-synuclein oligomers
Expression of CDNF in the substantia nigra has an anti-inflammatory effect on experimental Parkinson's disease.
Although no CDNF mutations are found in early-onset Parkinson's disease patient samples, a trend towards increased risk for Parkinson's in carriers of the C allele of rs7094179 single nucleotide polymorphism (SNP) is found.
expressed in several tissues; might be beneficial for the treatment of Parkinson's disease
structures of MANF (Montrer MANF Kits ELISA) and CDNF were solved; structure explains why MANF (Montrer MANF Kits ELISA) and CDNF are bifunctional; neurotrophic activity may reside in the N-terminal domain and ER stress response in the C-terminal domain
Study suggests that there is no association between variants in the CDNF gene and cocaine dependence.
secretion of mouse MANF (Montrer MANF Kits ELISA) and mouse CDNF is fundamentally regulated in the same manner, the variation of four C-terminal amino acids in the MANF (Montrer MANF Kits ELISA) and CDNF among species might influence their intracellular functions.
This study demonstrated that decrease in mRNA level of CDNF in brain in microgravity.
CDNF (Armetl1) is expressed in several tissues, including the mouse embryonic and postnatal brain
Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.
ARMET-like protein 1
, arginine-rich, mutated in early stage tumors-like 1
, conserved dopamine neurotrophic factor
, arginine-rich protein mutated in early stage tumors-like 1