Chemokine (C-C Motif) Ligand 23 Protéines (CCL23)

CCL23 is one of several cytokine genes clustered on the q-arm of chromosome 17. De plus, nous expédions Chemokine (C-C Motif) Ligand 23 Anticorps (61) et Chemokine (C-C Motif) Ligand 23 Kits (15) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
CCL23 6368 P55773
CCL23 574366 Q8HYP4
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Top Chemokine (C-C Motif) Ligand 23 Protéines sur

Showing 10 out of 40 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
Escherichia coli (E. coli) Humain Inconjugué   50 μg 2 to 3 Days
Escherichia coli (E. coli) Humain Inconjugué Validation with Western Blot 10 μg 4 to 8 Days
Escherichia coli (E. coli) Humain Inconjugué   50 μg 4 Days
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Levure Humain His tag 100 μg 14 to 16 Days
Escherichia coli (E. coli) Humain Inconjugué 20 μg 3 to 4 Days
Wheat germ Humain GST tag 2 μg 11 to 12 Days
Escherichia coli (E. coli) Humain His tag 50 μg 14 to 16 Days
Escherichia coli (E. coli) Humain His tag   100 μg 15 to 18 Days

CCL23 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , , , ,
, ,
Mouse (Murine)
Rhesus Monkey

Plus protéines pour Chemokine (C-C Motif) Ligand 23 (CCL23) partenaires d'interaction

Human Chemokine (C-C Motif) Ligand 23 (CCL23) interaction partners

  1. The low expression of CCL23 in hepatocellular carcinoma (HCC) tissue is not conducive to the development of anti-tumor immune defense in HCC patients and significantly shortens the survival of HCC patients.

  2. CCL23 is posttranslationally modified by trypsin-like serine proteases and CCL23(47-117) might be a major active form of CCL23 in nasal polyps with chronic rhinosinusitis.

  3. The coexistence of diabetes and oxidative stress independently affected CCL23 levels, while the presence of Cardiovascular disease and inflammation had no impact on its concentrations.

  4. ADAMTS 8, CCL23, and TNFSF15 are implicated in anti-angiogenic activities

  5. Data show CCL23 stimulates chemotaxis of human THP-1 monocytes and enhances release of MMP-2, and suggest it plays a role in atherogenesis.

  6. Overproduction of CCL23 in nasal polyps might contribute to the pathogenesis of eosinophilic chronic rhinosinusitis with nasal polyps

  7. Patients with systemic sclerosis who had elevated CCL23 levels had shorter disease duration, and a higher frequency of pulmonary arterial hypertension. Serum CCL23 level was increased in early phase of disease and could be a marker for disease activity.

  8. Fresh eosinophils contained trace amounts of CCL23 protein. CCL23 was significantly released into the supernatant when the eosinophils were stimulated with GM-CSF or IL-5 but not with IFN-gamma or immobilized sIgA.

  9. The role of KLF6 and PPAR-gamma in MIP-3alpha transcriptional regulation, was determined.

  10. independently associated with coronary atherosclerosis

  11. CKbeta8- and CKbeta8-1-induced activation of ERK1/2 is mediated by the G(i)/G(o) protein, PLC, and PKCdelta.

  12. CKbeta8 transduces the chemotaxis signal through the G(i)/G(o) protein, phospholipase C, protein kinase C delta and NF-kappaB.

  13. CCL23 promoted chemotactic migration and differentiation of endothelial cells, and neovascularization in the chick chorioallantoic membrane

  14. May play a direct role in angiogenesis via upregulation of matrix metalloproteinase (MMP)-2 expression.

  15. Collectively, these data suggest a link between the inducible phenotype of CCL23 expression in monocytes by the prototype Th2 molecule pair IL-4/STAT6 and the increased number of CCL23-expressing cells in skin of atopic dermatitis patients.

  16. A peptide ligand termed SHAAGtide is cleaved from CCL23; is itself an attractant of monocytes and neutrophils in vitro; recruits leukocytes in vivo; is more potent than other natural agents with activity for FPRL1; receives authors' designation "CCR12."

  17. This protein may participate in the malignant progression of certain human cancer cells that overexpress ErbB2 through the transactivation of ErbB2 tyrosine kinase.

  18. CCL23, M-CSF, TNFRSF9, TNF-alpha, and CXCL13 are predictive of rheumatoid arthritis disease activity and may be useful in the definition of disease subphenotypes and in the measurement of response to therapy in clinical studies.

  19. these findings suggest that CCL23 results in up-regulation of KDR/flk-1 receptor gene transcription and protein expression and that KDR/Flk-1 up-regulation induced by CCL23 may contribute to potentiation of VEGF action in angiogenesis.

Profil protéine Chemokine (C-C Motif) Ligand 23 (CCL23)

Profil protéine

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active isoforms have been identified.

Gene names and symbols associated with CCL23

  • C-C motif chemokine 23 (LOC508666)
  • C-C motif chemokine ligand 23 (CCL23)
  • chemokine (C-C motif) ligand 23 (CCL23)
  • CK-BETA-8 Protéine
  • Ckb-8 Protéine
  • Ckb-8-1 Protéine
  • CKb8 Protéine
  • hmrp-2a Protéine
  • MIP-3 Protéine
  • MIP3 Protéine
  • MPIF-1 Protéine
  • SCYA23 Protéine

Protein level used designations for CCL23

CK-beta-8 , macrophage inflammatory protein 3 , myeloid progenitor inhibitory factor 1 , C-C motif chemokine 23 , C6 beta-chemokine , small inducible cytokine subfamily A (Cys-Cys), member 23 , chemokine CCL23/MPIF-1 , small inducible cytokine A23 , small-inducible cytokine A23

508666 Bos taurus
6368 Homo sapiens
574366 Macaca mulatta
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