Chemokine (C-C Motif) Receptor 8 (CCR8) Kits ELISA

CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. De plus, nous expédions CCR8 Anticorps (113) et CCR8 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CCR8 1237 P51685
CCR8 12776 P56484
CCR8 301066  
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Top CCR8 Kits ELISA sur anticorps-enligne.fr

Showing 9 out of 19 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Souris 0.188 ng/mL 0.313-20 ng/mL Typical standard curve 96 Tests 12 to 14 Days
$630.00
Détails
Humain 0.094 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests 12 to 14 Days
$630.00
Détails
Rat 0.938 ng/mL 1.563-100 ng/mL Typical standard curve 96 Tests 12 to 14 Days
$638.00
Détails
Lapin 9.375 ng/mL 15.625-1000 ng/mL   96 Tests 12 to 14 Days
$715.00
Détails
Poulet 9.375 ng/mL 15.625-1000 ng/mL   96 Tests 12 to 14 Days
$715.00
Détails
Cobaye 1.875 ng/mL 3.125-200 ng/mL   96 Tests 12 to 14 Days
$715.00
Détails
Porc 0.094 ng/mL 0.156-10 ng/mL   96 Tests 12 to 14 Days
$715.00
Détails
Singe 0.094 ng/mL 0.156-10 ng/mL   96 Tests 12 to 14 Days
$715.00
Détails
Mouton 0.469 ng/mL 0.781 ng/mL - 50 ng/mL   96 Tests 11 to 18 Days
$852.81
Détails

Plus Kits ELISA pour CCR8 partenaires d'interaction

Human Chemokine (C-C Motif) Receptor 8 (CCR8) interaction partners

  1. Blocking CCR8 via a small molecule inhibitor or short hairpin (sh)RNA mitigated the decrease in Ecadherin, and increase in MMP2 and VEGFC, caused by human recombinant (r)CCL18. CCR8 knockdown by shRNA reversed rCCL18induced cancer cell invasion, migration and epithelialmesenchymal transition

  2. Long-lived memory T cells in human skin can be defined by the expression of CCR8.

  3. Authors demonstrate the pivotal role of CCR8(+) Treg cells in restraining immunity and highlight the potential clinical implications of this discovery.

  4. Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding.

  5. High CCR8 expression is associated with high recurrence in kidney cancer.

  6. findings suggest that CCR8 expression in ALCL is more closely related to the presence of DUSP22 rearrangements than to cutaneous involvement and that the function of CCR8 may extend beyond its skin-homing properties in this disease

  7. Epidermal-derived vitamin D3 metabolites and prostaglandins provide an essential cue for the localization of CCR8+ immune surveillance T cells within healthy human skin.

  8. CCL1-CCR8 interaction may play a critical role in lymphocytic recruitment in IgG4-related sclerosing cholangitis and type 1 autoimmune pancreatitis, leading to duct-centred inflammation and obliterative phlebitis.

  9. Identification of human CCR8 as a CCL18 receptor.

  10. CCR8(+) myeloid cell subset is expanded in patients with cancer.

  11. Data show that CCR8 expression by newly activated naive T cells is regulated by skin-specific factor(s) derived primarily from epidermal keratinocytes.

  12. C-terminal clipping of chemokine CCL1/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity

  13. The functional data from human macrophages suggest a potential cross talk between the CCR8 and the Toll-like receptor 4 (TLR4) pathways, both of which are present in chronic obstructive pulmonary disease patients.

  14. There may be a role for CCR8 in the recruitment of T cells to the lung in asthmatics.

  15. CCR8 mediates rescue from dexamethasone-induced apoptosis via an ERK-dependent pathway

  16. found in the central nervous system and is associated with phagocytic macrophages

  17. CCR8 genes and surrounding genomic regions these genes are the result of the duplication of an ancestral gene prior to the divergence of teleost fish.

  18. Transfected human CCR8-dependent activation of the RAS/MAPK pathway mediates anti-apoptotic activity of I-309/ CCL1 and vMIP-I.

  19. The induction of CCR8 under conditions associated with vascular smooth muscle cell proliferation and migration raises the possibility that CCR8 may play an important role in vessel wall pathology.

  20. the axis CCL1-CCR8 links adaptive and innate immune functions that play a role in the initiation and amplification of atopic skin inflammation

Mouse (Murine) Chemokine (C-C Motif) Receptor 8 (CCR8) interaction partners

  1. this study shows that the chemokine receptor CCR8 promotes the migration of dendritic cells into the lymph node parenchyma to initiate the allergic immune response

  2. CCR8 negatively regulates migration of cutaneous dendritic cells from the skin to the draining lymph nodes in contact hypersensitivity by keeping these cells in the skin.

  3. Chemokine receptor CCR8 is required for lipopolysaccharide-triggered cytokine production in mouse peritoneal macrophages.

  4. A sustained donor Treg presence is critical for their beneficial properties, and that their survival depends on CCR8 and donor but not host CD11c(+) Aantigen presenting cells.

  5. Expression of CCR-8 in microglia was upregulated in the presence of CCL-1.

  6. C-terminal clipping of chemokine CCL1/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity

  7. Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice.

  8. a key regulator of Th2 cell skin recruitment during IL-5-mediated allergic inflammation

  9. mediates increased responsiveness of murine eosinophils to TCA-3

  10. Data from three different models plus an in vivo blocking study clearly show that the Th2 cell-mediated pathological response to ovalbumin-induced allergic airway inflammation is not critically CCR8-dependent.

  11. sulfation at specific positions of the N-terminal domain of mouse CCR8 is critical for its biological activity, whereas glycosylation has a minor influence

  12. IL-10 production correlates with CCR8 ligand (CCL1) expression and the appearance of CCR8+ cells in granulomatous lungs and is required for full expression of the T helper type 2 cell response to parasite antigens.

  13. CCR8 may have a negative impact on host defense during septic peritonitis, providing a new paradigm for the role of CCR8 in innate immunity.

  14. CCR8 ligands are allotropic, binding to distinct sites within CCR8

  15. CCR8 is expressed by a small and heterogeneous population of peripheral blood CD4 memory T cells enriched in T helper type 2 (Th2) effector and T regulatory (Treg) cells.

  16. Ccr8 has a pivotal role in the progression of experimental fungal asthma.

  17. Mast cell-derived CCR8- and CCL1-expressing CD4-positive effector T lymphocytes play an essential role in orchestrating lung mucosal inflammatory responses.

  18. Results suggest that CCR8 plays a significant role in the pathogenesis of experimental autoimmune encephalomyelitis and probalby of multiple sclerosis.

  19. CCR8/CCL1 interaction may play a role in type 1 diabetes through macrophage recruitment and activation

  20. Contribution of CCR4 and CCR8 to antigen-specific T(H)2 cell trafficking in allergic pulmonary inflammation.

CCR8 profil antigène

Antigen Summary

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

Gene names and symbols associated with CCR8

  • C-C motif chemokine receptor 8 (CCR8) anticorps
  • chemokine (C-C motif) receptor 8 (Ccr8) anticorps
  • C-C motif chemokine receptor 8 (Ccr8) anticorps
  • C-C anticorps
  • C-C CKR-8 anticorps
  • CC-CKR-8 anticorps
  • CCR-8 anticorps
  • CDw198 anticorps
  • CKR-8 anticorps
  • CKRL1 anticorps
  • Cmkbr8 anticorps
  • CMKBRL2 anticorps
  • CY6 anticorps
  • GPRCY6 anticorps
  • mCCR8 anticorps
  • TER1 anticorps

Protein level used designations for CCR8

C-C chemokine receptor type 8 , CC chemokine receptor 8 , CC chemokine receptor CHEMR1 , CC-chemokine receptor chemr1 , chemokine (C-C) receptor 8 , chemokine (C-C) receptor-like 2 , chemokine receptor-like 1 , C-C motif chemokine receptor 8

GENE ID SPECIES
1237 Homo sapiens
12776 Mus musculus
693806 Macaca mulatta
301066 Rattus norvegicus
420718 Gallus gallus
407772 Bos taurus
100345500 Oryctolagus cuniculus
100725278 Cavia porcellus
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