Chemokine (C-X-C Motif) Receptor 3 (CXCR3) Kits ELISA

CXCR3 encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). De plus, nous expédions CXCR3 Anticorps (202) et CXCR3 Protéines (10) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CXCR3 2833 P49682
CXCR3 12766 O88410
CXCR3 84475 Q9JII9
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Top CXCR3 Kits ELISA sur

Showing 10 out of 31 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 15.6 pg/mL 62.5-4000 pg/mL Typical standard curve 96 Tests 13 to 16 Days
Rat 0.059 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
Souris 0.125 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
Lapin 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
Cobaye 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
Porc 0.094 ng/mL 0.156-10 ng/mL   96 Tests 12 to 14 Days
Poulet 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
Singe 0.1 ng/mL 1.0-25 ng/mL   96 Tests 15 to 18 Days
Chien 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days

CXCR3 Kits ELISA mieux référencés

  1. Human CXCR3 Kit ELISA pour Sandwich ELISA - ABIN366833 : Zhang, Liu, Su, Shi, Chen: Serum fractalkine and interferon-gamma inducible protein-10 concentrations are early detection markers for acute renal allograft rejection. dans Transplantation proceedings 2014 (PubMed)

Plus Kits ELISA pour CXCR3 partenaires d'interaction

Human Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. biased agonists of CXCR3 produce distinct physiological effects, suggesting discrete roles for different endogenous CXCR3 ligands

  2. CXCR3 protein level significantly increased in osteoarthritis patients.

  3. Data provide evidence that CXCR3 mediates the function of CXCL4 in colon cancer cells.

  4. CXCR3 enhanced CXCR4 function in colorectal cancer cells invasion through forming heteromers with CXCR4 on cell surface thus preventing CXCR4 internalization.

  5. CXCR3 and its chemokines are involved in the recruitment of granulocytes and mononuclear cells, therefore in the maintenance of inflammation in Crohn disease

  6. In primary biliary cirrhosis (PBC), circulating MIG levels and CXCR3+ cells are related with the progression of the disease; their expression increases significantly in PBC patients with respect to controls

  7. Expression of CXCL10 was up-regulated in hepatocellular carcinoma (HCC) tissues, expression of CXCR3 was down-regulated in HBV-related HCC tissues

  8. results suggest that the CXCL10/CXCR3 axis may contribute to the pathogenesis of Behcet's disease

  9. miR-16-5p can protect LPS-induced A549 cell injury, and its mechanism may be related to the targeted regulation of CXCR3

  10. The result of this study showed that CXCR3/CXCL10/CXCL11 signaling axis is overexpressed in the small intestinal mucosa of celiac disease patients compared to controls. This finding might explain the specific enrollment of the main cell populations that infiltrate the epithelium

  11. Study found a respectively increased and decreased expression of CXCR3 splice variants CXCR3A and CXCR3B in colorectal cancer (CRC) tumors. CXCR3A and CXCR3B played disparate roles in regulating progressive characteristics of CRC cells, including the proliferation, invasion, migration, and tumorigenicity. This study suggests that the alternation of CXCR3 splice isoforms is necessary in the metastasis of CRC.

  12. Study suggests that vitiligo is likely to be initiated in the normal-appearing skin of vitiligo subjects through activation of local innate lymphocyte-induced melanocyte apoptosis and subsequent activation of adaptive and memory immune responses. This apoptosis is mediated by melanocytic CXCR3B, identifying this isoform of CXCR3 chemokine receptor to be critical in melanocyte destruction and initiation of the disease.

  13. Study shows that the expression level of CXCR3 in T cells was significantly elevated in several neurological diseases. Study reviews evidence that CXCR3 plays a vital role in the pathogenesis of multiple sclerosis, glioma, Alzheimer disease, chronic pain, human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis and bipolar disorder.

  14. Increased CXCR3 expression is associated with progression of primary open-angle glaucoma.

  15. IL1B promotes the transendothelial migration of mesenchymal stem cells through CXCR3-CXCL9 axis.

  16. Study found that vitiligo skin is enriched with CD8 resident memory T cells that express CXCR3. Strikingly, a higher frequency of skin melanocyte-specific CD8 T cells was found within the CXCR3+ subset.

  17. The populations were identified based on the production of IFN-gamma and/or IL-17 and the coexpression of CXCR3 (X3) and CCR6 (R6).

  18. High CXCR3 expression is associated with invasion and metastasis in tongue squamous cell carcinoma.

  19. Up-regulated CXCR3 is detectable in the amniotic fluid and associated with the presence of placental lesions consistent with maternal anti-fetal rejection so may serve as a potential marker of spontaneous preterm delivery.

  20. the expression of chemokine receptors in different peripheral blood T-cell subsets in patients with polymyositis (PM) and dermatomyositis, was examined.

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. Our data suggest that the CXCR3 chemokine system is a biomarker for sensitivity to PD-1 blockade and that augmenting the intratumoral function of this chemokine system could improve clinical outcomes.

  2. Results suggest that CXCR3 confers early protection against S. typhimurium infection which is crucial in preventing bacterial dissemination to the spleen and liver of mice. Both the early recruitment of CXCR3-expressing neutrophils and CXCR3-mediated IFN-gamma secretion are instrumental in an effective immune response against gram-negative S. typhimurium.

  3. Salmonella enterica (Se) infection stimulates robust expansion of chemokine (C-X-C motif) receptor 3 (CXCR3+) Th1 cells.

  4. Further analysis revealed that IRF1 deficiency suppress interferon-gamma production and delayed CD8+ T cell proliferation. CXCR3 expression was found to be decreased in pathogenic CD8+ T cells, which limited their migration to the brain

  5. CXCR3-deficient mesenchymal stem cells did not ameliorate lupus symptoms in MRL. Fas(lpr) mice in comparison with wild-type mesenchymal stem cells. The data suggest that upregulation of CXCR3 in mesenchymal stem cells will be a good strategy to increase their infiltration into the kidney in mice, which will improve therapeutic outcomes in systemic lupus erythematosus (SLE).

  6. The data illustrate the paradoxical pro-tumor role for CXCR3 in lung immunobiology wherein the CXCR3 axis drives both the anti-tumor effector cell chemoattraction and pro-tumor infiltration of the lungs and suggests a potential therapeutic target for lung-tropic metastasizing cancers.

  7. the data suggest that CXCR3 and the integrin alpha4 mediate T cell recruitment to uninfected salivary glands but that redundant mechanisms mediate T cell recruitment after Murine Cytomegalovirus infection.

  8. The data of this study suggested that spinal CXCR3 mediates chronic itch and alloknesis, and targeting CXCR3 may provide effective treatment for chronic pruritus.

  9. Study provided the evidence that CXCL10/CXCR3 signaling in periaqueductal gray is involved in the development of morphine analgesic tolerance via neuron-microglia interaction.

  10. The results demonstrate that the recruitment of peripheral immune cells into the CNS, induction of neuroinflammation, and consecutive weight loss during herpes encephalitis is modulated by CXCR3 signaling.

  11. results show an important role for CXCR3 and CXCL10 in the tissue distribution of preimmune memory phenotype CD8 T- cells

  12. Our data suggests that the altered gene profiles induced by CXCR3 deficiency promotes autoimmune cholangitis through pathogenic CD8(+) T cells.

  13. Data suggest that the CXCL9-CXCR3 axis plays a pivotal role in the liver-specific distribution of TRAIL+ NK cells in mice.

  14. ATF3-KO mice escape from PE-dependent maladaptive cardiac remodeling by suppressing the IFNgamma-CXCL10-CXCR3 axis at multiple levels.

  15. study thus shows that lung mucosal-resident memory T cells are not generated following systemic TB immunization and that local inflammation is required for systemically activated T cells to home to lung mucosa, which is mediated by interaction between CXCR3 upregulated in these cells and its ligands IP-10 and MIG

  16. Antigen targeting to DEC-205 on dendritic cells leads to an IL-10-dependent downregulation of CXCR3 expression on differentiated antigen-specific Th1 cells in vivo. This downregulation interferes with the migration of Th1 cells into the gut and protects mice against severe acute and relapsing intestinal inflammation.

  17. this study shows that neutrophils and NK cells act as important disease-promoting immune cells in experimental osteoarthritis and their functional interaction is promoted by the CXCL10/CXCR3 axis

  18. These results demonstrate a critical role for both BLT1 and CXCR3 in cytotoxic T lymphocyte (CTL) migration to tumors and thus may be targeted to enhance efficacy of CTL-based immunotherapies.

  19. Our studies suggest that CXCR3 is a key contributor to the pathogenesis of Alopecia areata by mediating the infiltration of autoreactive CD8+NKG2D+ T cells into the skin

  20. Cxcr3 is up-regulated by DNA demethylation and interaction with C/EBPalpha which contributes to neuropathic pain.

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CXCR3 expression

Zebrafish Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. The demonstration of a conserved CXCR3-CXCL11 signaling axis in zebrafish extends the translational applicability of this model for studying diseases involving the innate immune system.

CXCR3 profil antigène

Antigen Summary

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

Gene names and symbols associated with CXCR3

  • C-X-C motif chemokine receptor 3 (CXCR3) anticorps
  • chemokine (C-X-C motif) receptor 3 (Cxcr3) anticorps
  • chemokine (C-X-C motif) receptor 3 (cxcr3) anticorps
  • C-X-C motif chemokine receptor 3 (Cxcr3) anticorps
  • chemokine (C-X-C motif) receptor 3, tandem duplicate 1 (cxcr3.1) anticorps
  • CD182 anticorps
  • Cd183 anticorps
  • CKR-L2 anticorps
  • Cmkar3 anticorps
  • CXC-R3 anticorps
  • CXCR-3 anticorps
  • cxcr3 anticorps
  • Gpr9 anticorps
  • IP10-R anticorps
  • Mig-R anticorps
  • MigR anticorps
  • sb:eu378 anticorps

Protein level used designations for CXCR3

C-X-C chemokine receptor type 3 , CXC-R3 , CXCR-3 , G protein-coupled receptor 9 , IP-10 receptor , IP10 receptor , Mig receptor , chemokine (C-X-C) receptor 3 , interferon-inducible protein 10 receptor , chemokine (C-X-C motif) receptor 3 , CXC chemokine receptor 3 , Interferon-inducible protein 10 receptor , CXCR3ab , chemokine (C-X-C motif) receptor 3.1 , dr-chr16-CXCR3-41.8%-EK27498 , dr-chr16-CXCR3-41.8-EK27498

2833 Homo sapiens
12766 Mus musculus
465704 Pan troglodytes
491952 Canis lupus familiaris
496477 Xenopus (Silurana) tropicalis
497018 Bos taurus
699438 Macaca mulatta
84475 Rattus norvegicus
100860874 Capra hircus
654692 Danio rerio
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