anti-Chemokine-Like Receptor 1 (CMKLR1) Anticorps

may be a member of the chemokine receptor family [RGD, Feb 2006].. De plus, nous expédions CMKLR1 Kits (7) et CMKLR1 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CMKLR1 1240 Q99788
CMKLR1 14747 P97468
CMKLR1 60669  
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Top anti-CMKLR1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 113 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué WB WB Suggested Anti-CMKLR1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate 100 μL 2 to 3 Days
$319.00
Détails
Humain Lapin Inconjugué IP, IHC, WB Immunohistochemical analysis of CMKLR1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of CMKLR1 expression in Jurkat (A), HepG2 (B), mouse liver (C), rat liver (D) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB Western Blot (WB) analysis of 293T lysis using ChemR23 antibody. 100 μL Disponible
$363.46
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from HeLa/HuvEc cells, using CMKLR1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Détails
Souris Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat spleen labeled with Rabbit Anti CMKLR1 Polyclonal Antibody, Unconjugated (ABIN1715118) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 14 to 21 Days
$329.45
Détails
Humain Rat Inconjugué FACS, IHC, IHC (p) Human Placenta (formalin-fixed, paraffin-embedded) stained with CMKLR1 antibody ABIN337260 at 10 ug/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Anti-CMKLR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ICC, IHC, IHC (p) Anti-CMKLR1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué IHC, IHC (p) Anti-CMKLR1 antibody  ABIN1048449 IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Détails
Chien Lapin Inconjugué IHC, IHC (p) Anti-CMKLR1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL 11 to 14 Days
$581.17
Détails

anti-CMKLR1 Anticorps mieux référencés

  1. Human Monoclonal CMKLR1 Primary Antibody pour CyTOF, FACS - ABIN4899107 : Skrzeczyńska-Moncznik, Wawro, Stefańska, Oleszycka, Kulig, Zabel, Sułkowski, Kapińska-Mrowiecka, Czubak-Macugowska, Butcher, Cichy: Potential role of chemerin in recruitment of plasmacytoid dendritic cells to diseased skin. dans Biochemical and biophysical research communications 2009 (PubMed)
    Show all 4 Pubmed References

  2. Mouse (Murine) Polyclonal CMKLR1 Primary Antibody pour IF (p), IHC (p) - ABIN1715118 : Qu, Zhang, Yao, Song, Nikolic-Paterson, Li: Resolvins E1 and D1 inhibit interstitial fibrosis in the obstructed kidney via inhibition of local fibroblast proliferation. dans The Journal of pathology 2014 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal CMKLR1 Primary Antibody pour FACS - ABIN4895587 : Herová, Schmid, Gemperle, Hersberger: ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages. dans Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal CMKLR1 Primary Antibody pour FACS - ABIN2473014 : Rosenkranz, Klopman: A re-examination of the genotoxicity and carcinogenicity of azathioprine. dans Mutation research 1991 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal CMKLR1 Primary Antibody pour FACS - ABIN2473017 : Zabel, Silverio, Butcher: Chemokine-like receptor 1 expression and chemerin-directed chemotaxis distinguish plasmacytoid from myeloid dendritic cells in human blood. dans Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre CMKLR1 partenaires d’interaction

Human Chemokine-Like Receptor 1 (CMKLR1) interaction partners

  1. Chemerin/ChemR23 promotes tumorigenesis and metastasis in oral squamous cell carcinoma cells.

  2. Report a modest inverse association between chemerin and ankle-brachial index that remained consistent after adjustment for metabolic and inflammatory parameters in subclinical atherosclerosis.

  3. This study identified an ERV1/ChemR23 variant that protects patients with obesity from excessive inflammatory burden.

  4. Chemerin upregulated expression and phosphatase activity of PTEN by interfering with PTEN-CMKLR1 interaction, leading to weakened ubiquitination of PTEN and decreased p-Akt (Ser473) level, which was responsible for suppressed migration, invasion and metastasis of HCC cells.

  5. Chemerin levels were lower in subfertile men compared to controls. Men with elevated LH levels had lower chemerin levels compared to those with LH levels within the normal range.

  6. The expression level of chemerin in women who had experienced early spontaneous abortion was lower than in those who had experienced normal early pregnancy; conversely, CMKLR1 expression was higher in the former than in the latter.

  7. levels in cord blood, peripheral blood, adipose tissue and placenta tissue significantly higher in gestational diabetes

  8. CMKLR1 and GPR1 were widely expressed in vascular smooth muscle.

  9. Both ALX and ChemR23 were present in human synovium and medial tibial plateau bone obtained following total knee replacement surgery for osteoarthritis.

  10. Results show that ChemR23 is highly expressed in squamous oesophageal cancer tumors and cell lines.

  11. CMKLR1 exacerbated the proliferation and migration of VSMCs by activating ERK1/2.

  12. We demonstrated that chemerin is linked to metabolic syndrome components. Moreover, serum chemerin levels were associated significantly with obesity, especially visceral adipose tissue, in subjects with T2DM [type 2 diabetes mellitus].

  13. Study shows that hepatic CMKLR1 mRNA is weakly associated with features of NASH in male patients only.

  14. Our results show that higher levels of circulating chemerin, CRP, fibrinogen, and ESR are associated with an increased risk of developing colorectal cancer

  15. Data show inverse Relationship of the CMKLR1 Relative Expression and Chemerin Serum Levels in Obesity with Dysmetabolic Phenotype and Insulin Resistance

  16. Results indicate that Abeta42 activates CMKLR1, leading to glia cell migration and clearance of Abeta42; and is involved in Abeta processing and clearance

  17. Gestational obesity and gestational diabetes mellitus may contribute to elevated serum chemerin. Serum chemerin in pregnancy was associated with insulin resistance and triglycerides. Chemerin gene may play a role both in obese and gestational diabetes mellitus patients

  18. Increased chemerin expression in dermal blood vessels may be associated with the development of digital ulcers in systemic sclerosis.

  19. The study for the first time confirmed a marked expression of chemerin and CMKLR1 in the liver of chronic hepatitis patients.

  20. ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.

Mouse (Murine) Chemokine-Like Receptor 1 (CMKLR1) interaction partners

  1. Upregulation of chemerin and CMKLR1 may explain the imbalance of oxidative stress and apoptosis in the ovaries of obese mice.

  2. findings show that chemerin-activated CMKLR1 regulation in inflammatory macrophages is largely GRK6 and beta-arrestin mediated, which may impact innate immunity and have therapeutic implications in rheumatic disease.

  3. In a pregnant-mouse model, the embryo resorption rate of alpha-NETA group was higher than that in the negative control group. These results suggested that the inhibition of the chemerin/CMKLR1 signaling pathway can lead to the abortion of mouse embryos, and that chemerin/CMKLR1 may play an important role in the maintenance of early pregnancy possibly by regulating ERK1/2 phosphorylation.

  4. PI3K inhibition attenuates hepatic steatosis and KC-mediated inflammation via down-regulation of CMKLR1 and NLRP3 in HFD mice

  5. These findings support a fundamental biological function for chemerin/CMKLR1 to balance osteoblastogenic and adipogenic signaling and thereby contribute to the maintenance of pluripotency in mesenchymal stem cells.

  6. Chemerin-CMKLR1 activates Akt/mTOR and ERK pathways and facilitates preadipocyte proliferation, adipogenesis, and angiogenesis. Gax weakens the effect of chemerin on preadipocyte biofunctions.

  7. CMKLR1 exacerbated the proliferation and migration of VSMCs by activating ERK1/2.

  8. CMKLR1 gene deletion attenuates the effects of chronic DHT treatment on ovarian function in experimental PCOS, likely via BMP4 signaling.

  9. Loss of CMKLR1 exacerbates glucose intolerance and insulin resistance in mice fed high fat diets.

  10. The chemerin15 (C15) precursor, chemerin, and its receptor, ChemR23, are both upregulated after skin damage and the receptor is expressed by macrophages, neutrophils, and keratinocytes. C15 delivery dampens immediate inflammatory events.

  11. Results indicate that Abeta42 activates CMKLR1, leading to glia cell migration and clearance of Abeta42; and is involved in Abeta processing and clearance

  12. Increased chemerin expression in dermal blood vessels may be associated with the development of digital ulcers in systemic sclerosis.

  13. In brown adipose tissue, cold acclimation strongly diminished chemerin gene expression, whereas obesogenic diets augmented expression.

  14. Hematopoietic Deletion of Cmklr1 Does not Affect the Development of Insulin Resistance or nonalcoholic fatty liver disease.

  15. ChemR23 is expressed in neutrophil granules and rapidly upregulated upon neutrophil activation.

  16. Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain.

  17. Data suggest that chemerin/ChemR23 signaling is not essential for adipocyte differentiation, but it appears to play a role in control of body weight and energy metabolism as overweight/obesity progresses.

  18. ChemR23 forms homomers, and provide data suggesting that ChemR23 also forms heteromers witChemR23 forms homomers, and provide data suggesting that ChemR23 also forms heteromers with the chemokine receptors CCR7 and CXCR4.

  19. Downstream targets of Chemerin/ChemR23 signaling are phosphorylated in vitro and are expressed in mouse tooth development, suggesting roles for Chemerin/ChemR23-mediated epithelial-mesenchymal cell signaling during tooth morphogenesis.

  20. These results rule out the direct anti-inflammatory effect of chemerin on macrophages ex vivo, described previously in the literature, despite the expression of a functional ChemR23 receptor in these cells.

Cow (Bovine) Chemokine-Like Receptor 1 (CMKLR1) interaction partners

  1. Data show that the fat and energy moblization during lactation influences circulating retinoic acid receptor responder protein 2 (RARRES2) levels as well as the expression of RARRES2 and chemokine-like receptor 1 (CMKLR1) in subcutaneous adipose tissue (SAT) and ovarian cells.

CMKLR1 profil antigène

Profil protéine

may be a member of the chemokine receptor family

Gene names and symbols associated with CMKLR1

  • chemerin chemokine-like receptor 1 (CMKLR1) anticorps
  • chemokine-like receptor 1 (Cmklr1) anticorps
  • chemerin chemokine-like receptor 1 (Cmklr1) anticorps
  • chemokine-like receptor 1 (cmklr1) anticorps
  • chemerin chemokine-like receptor 1 (cmklr1) anticorps
  • CHEMERINR anticorps
  • ChemR23 anticorps
  • Cmklr-1 anticorps
  • CMLKR1 anticorps
  • DEZ anticorps
  • GPCR anticorps
  • Gpcr27 anticorps
  • mcmklr1 anticorps
  • RVER1 anticorps
  • si:ch211-240b21.3 anticorps

Protein level used designations for CMKLR1

G-protein coupled receptor ChemR23 , G-protein coupled receptor DEZ , chemerin receptor , chemokine receptor-like 1 , orphan G-protein coupled receptor, Dez , resolvin E1 receptor , G-protein coupled receptor 27 , G-protein coupled chemoattractant-like receptor , chemokine-like receptor 1 , seven transmembrane helix receptor

GENE ID SPECIES
1240 Homo sapiens
14747 Mus musculus
60669 Rattus norvegicus
486321 Canis lupus familiaris
557341 Danio rerio
615411 Bos taurus
100216025 Xenopus (Silurana) tropicalis
780421 Sus scrofa
100583846 Nomascus leucogenys
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