anti-Cholinergic Receptor, Nicotinic, alpha 6 (Neuronal) (CHRNA6) Anticorps

CHRNA6 encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. De plus, nous expédions CHRNA6 Protéines (8) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CHRNA6 81721 P43143
CHRNA6 11440 Q9R0W9
CHRNA6 8973 Q15825
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Top anti-CHRNA6 Anticorps sur anticorps-enligne.fr

Showing 10 out of 34 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-CHRNA6 Antibody   Titration: 1.0 ug/ml   Positive Control: Jurkat Whole Cell 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using CHRNA6 mAb against human CHRNA6 (AA: 26-239) recombinant protein. (Expected MW is 51.2 kDa) 100 μg Connectez-vous pour afficher 3 to 4 Days
$430.10
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cells, using CHRNA6 antibody. 100 μL Connectez-vous pour afficher 11 to 13 Days
$366.77
Détails
Humain Lapin Inconjugué WB   100 μg Connectez-vous pour afficher 11 to 14 Days
$1,013.83
Détails
Humain Lapin Inconjugué WB CHRNA6 antibody (70R-10564) used at 0.2-1 ug/ml to detect target protein. 50 μg Connectez-vous pour afficher 9 to 11 Days
$473.93
Détails
Humain Lapin Inconjugué IHC, WB   100 μL Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, IF, WB   200 μL Connectez-vous pour afficher 6 to 7 Days
$509.40
Détails
Humain Chèvre Inconjugué IHC   50 μg Connectez-vous pour afficher 11 to 16 Days
$688.29
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using CHRNA6 antibody (ABIN6293955) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s. 50 μL Connectez-vous pour afficher 11 to 13 Days
$308.12
Détails
Humain Lapin Inconjugué ELISA, IHC, WB   100 μL Connectez-vous pour afficher 11 to 16 Days
$440.62
Détails

Plus d’anticorps contre CHRNA6 partenaires d’interaction

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 6 (Neuronal) (CHRNA6) interaction partners

  1. study provides evidence that alpha6beta2 nAChRs are involved in locomotor activity as well as ethanol and saccharin consumption in adolescent animals

  2. Using behavioral and cellular measures of alpha6 * nAChR function, study demonstrated that the ventral tegmental area is a key site of action for nicotine at alpha6 * nAChRs

  3. The present data show that alpha6beta2( *) nAChRs are key regulators of LIDs, and may be useful therapeutic targets for their management in Parkinson's disease.

  4. these data indicate that a6)nAChR do not have an impact on motor output.

  5. enhanced alpha6beta2* nAChR activity in nucleus accumbens can stimulate dopamine production

  6. Chrna6 expression decreases with death of RGCs in glaucomatous DBA/2J mice and after optic nerve crush injury, further supporting Chrna6 as a reliable RGC marker.

  7. While the Chrna6 gene did not significantly influence ethanol consumption (g/kg) or ataxia, mice lacking the alpha6 subunit took significantly longer to recover their righting reflex than WT animals

  8. The superior colliculus is responsible for transmitting short-latency salience signals to thalamus and midbrain DA neurons. these results suggest that alpha6* nAChRs may be important for nicotinic cholinergic sensitization of this pathway.

  9. beta3 subunit coexpression promotes function of alpha6*-nAChR

  10. This study highlights the precise control that the nicotinic cholinergic system exerts on DA transmission and provides further insights into the mechanisms and consequences of enhanced DA release.

  11. analysis of N-terminal extracellular domain determinants in nicotinic acetylcholine receptor (nAChR) alpha6 subunits that influence effects of wild-type or mutant beta3 subunits on function of alpha6beta2*- or alpha6beta4*-nAChR

  12. Data show that in Prkce(-/-) mice, conditioned place preference and self-administer behaviors are associated with reduced levels of alpha(6) and beta(3) nicotinic receptor subunit mRNA in the ventral midbrain and striatum.

  13. These results implicate alpha6alpha4beta2* nAChRs in cholinergic control of DA transmission

Zebrafish Cholinergic Receptor, Nicotinic, alpha 6 (Neuronal) (CHRNA6) interaction partners

  1. and chrna4 RNAs were each expressed in a unique pattern, which changed during development

Human Cholinergic Receptor, Nicotinic, alpha 6 (Neuronal) (CHRNA6) interaction partners

  1. This study is the first showing that CHRNB3/A6 are highly associated with nicotine dependence in a large Chinese Han sample.

  2. To gain a better understanding of the pathological processes underlying ND and ND-related behaviors and to promote the development of effective smoking cessation therapies, we here present the most recent studies concerning the genetic effects of the CHRNB3-CHRNA6 gene cluster in ND.

  3. More low frequency variants in the CHRNA6/CHRNB3 gene region were observed in cases compared to controls.

  4. Chrna6 has a cellular expression signature for retinal ganglion cells with high correlation to Thy1, a known marker. Immunofluorescence confirms this gene is preferentially expressed by RGCs in the young and adult mouse retina and expression is reduced in glaucoma.

  5. Data show efficient expression of (alpha6beta2)2beta3 nicotinic acetylcholine receptors (AChRs) in Xenopus oocytes using free subunits with only small changes in alpha6 subunits, while not altering AChR pharmacology or channel structure.

  6. the CHRNB3-A6 locus contains multiple variants affecting risk for vulnerability to cocaine and nicotine dependence as well as bipolar disorder, suggesting that they have pleiotropic effects.

  7. Polymorphism in CHRNA6 gene is associated with esophageal adenocarcinoma.

  8. The common variant rs13273442 in the CHRNB3-CHNRA6 region is associated significantly with nicotine dependence in European Americans and African Americans.

  9. N-terminal alpha-helix (Asp57); complementary face/inner beta-fold (Arg87 or Asp92) and principal face/outer beta-fold (Ser156 or Asn171) residues in the halpha6 subunit are crucial for functional expression.

  10. these results demonstrate that the combined effect of rs6474412-C/T polymorphism in smoking-related CHRNB3-CHRNA6 region gene and smoking behavior may not confer risk to psoriasis vulgaris (PV), but may have impact on PV severity in Chinese Han population.

  11. findings indicate that both CHRNA2 and CHRNA6 play a significant role in the etiology of ND in AA and EA smokers

  12. Results demonstrate the association between SNPs in CHRNA6 nicotinic acetylcholine receptor genes and the risk of smoking in ADHD

  13. Elucidation of molecular impediments in the alpha6 subunit for in vitro expression of functional alpha6beta4* nicotinic acetylcholine receptors.

  14. Cross sectional data of US adults from the NHANES linked with genotype and geocodes were used to identify tobacco use phenotypes, state-level taxation rates, and variation in the nicotinic acetylcholine receptor (CHRNA6) genotype

  15. beta3 subunit coexpression promotes function of alpha6*-nAChR

  16. alpha6beta4* nAChRs are expressed and contribute to exocytosis in human chromaffin cells of the adrenal gland, the main source of adrenaline under stressful situations.

  17. analysis of how nicotinic acetylcholine receptor (nAChR) alpha5 subunits and/or variants modulate function of alpha6*-nAChR

  18. analysis of N-terminal extracellular domain determinants in nicotinic acetylcholine receptor (nAChR) alpha6 subunits that influence effects of wild-type or mutant beta3 subunits on function of alpha6beta2*- or alpha6beta4*-nAChR

  19. CHRNB3 and CHRNA6 polymorphisms are associated with smoking behavior and lung cancer susceptibility in Chinese Han population.

  20. Three single nucleotide polymorphisms (SNPs) in CHRNA6 and one SNP in CHRNB3 are associated with a composite of alcohol phenotypes.

CHRNA6 profil antigène

Profil protéine

This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.

Gene names and symbols associated with CHRNA6

  • cholinergic receptor nicotinic alpha 6 subunit (Chrna6) anticorps
  • cholinergic receptor nicotinic alpha 6 subunit (CHRNA6) anticorps
  • cholinergic receptor, nicotinic, alpha polypeptide 6 (Chrna6) anticorps
  • cholinergic receptor, nicotinic, alpha 6 (chrna6) anticorps
  • Acra6 anticorps
  • CHNRA6 anticorps
  • Nica6 anticorps
  • si:dkey-234d14.1 anticorps

Protein level used designations for CHRNA6

cholinergic receptor, nicotinic, alpha polypeptide 6 , neuronal acetylcholine receptor subunit alpha-6 , alpha 6 nicotinic acetylcholine receptor subunit , acetylcholine receptor alpha 6 neural , alpha6 nAChR , nicotinic acetylcholine receptor subunit alpha 6 , neuronal acetylcholine receptor protein, alpha-6 subunit , neuronal nicotinic acetylcholine receptor alpha 6 , acetylcholine receptor, nicotinic, alpha 6 (neuronal) , cholinergic receptor, nicotinic, alpha 6 , neuronal acetylcholine receptor subunit alpha-6-like

GENE ID SPECIES
81721 Rattus norvegicus
396321 Gallus gallus
482836 Canis lupus familiaris
539113 Bos taurus
11440 Mus musculus
472750 Pan troglodytes
555747 Danio rerio
8973 Homo sapiens
705725 Macaca mulatta
100033042 Monodelphis domestica
100049908 Equus caballus
100355656 Oryctolagus cuniculus
100399236 Callithrix jacchus
100445583 Pongo abelii
100470009 Ailuropoda melanoleuca
100591999 Nomascus leucogenys
100622106 Sus scrofa
Fournisseurs de qualité sélectionnés pour anti-CHRNA6 (CHRNA6) Anticorps
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