Chromosome 10 Open Reading Frame 2 Protéines

C10ORF2 encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication.

Qualité de données
  • 7
Type
  • 7
    Protéine
Antigène
  • 7
Réactivité
  • 6
  • 1
Application
  • 6
  • 6
  • 5
  • 2
  • 2
Hote
  • 2
  • 2
  • 2
  • 1
Epitope
  • 2
  • 1
  • 1
  • 1
  • 1
Conjugué
  • 1
  • 3
  • 2
  • 1
Type Proteine
  • 7
Format
  • 4
7 Produits
Recombinant Protéine, Cellules d'insectes (Source), Pureté >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivitéHumain
Application Crys, ELISA, SDS, WB
Détails de la commande Cat. No. ABIN3094481
$9,371.15
Plus frais de port $45.00 et $22.00 pour carboglace
Envoi sous 60 jours ouvrables
Recombinant Protéine, Cellules d'insectes (Source), Pureté >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivitéSouris
Application Crys, ELISA, SDS, WB
Détails de la commande Cat. No. ABIN3126112
$9,371.15
Plus frais de port $45.00 et $22.00 pour carboglace
Envoi sous 60 jours ouvrables
ReactivitéHumain
Application AA, AP, ELISA, WB
Détails de la commande Cat. No. ABIN1347016
$338.33
2 μg
Plus frais de port $45.00 et $22.00 pour carboglace
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain
Application AA, AP, ELISA, WB
Détails de la commande Cat. No. ABIN1347017
$414.29
Plus frais de port $45.00 et $22.00 pour carboglace
Envoi sous 11 à 12 jours ouvrables
Recombinant Protéine, Levure (Source), Pureté > 90 %
ReactivitéHumain
Application SDS
Détails de la commande Cat. No. ABIN5714434
$539.00
Plus shipping costs $45.00
Envoi sous 8 à 11 jours ouvrables
Recombinant Protéine, Escherichia coli (E. coli) (Source), Pureté ≥ 96 %
ReactivitéHumain
Application ELISA, IP, SDS, WB
Détails de la commande Cat. No. ABIN4989489
$649.00
Plus shipping costs $45.00
Envoi sous 15 à 18 jours ouvrables
Recombinant Protéine, Escherichia coli (E. coli) (Source)
ReactivitéHumain
Application ELISA, IP, SDS, WB
Détails de la commande Cat. No. ABIN6118151
$661.28
Plus shipping costs $45.00
Envoi sous 11 à 18 jours ouvrables
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Profil protéine Chromosome 10 Open Reading Frame 2 (C10ORF2)

Profil protéine

This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with C10ORF2

  • twinkle mtDNA helicase L homeolog (twnk.L) anticorps
  • twinkle mtDNA helicase (TWNK) anticorps
  • twinkle mtDNA helicase (Twnk) anticorps
  • ATXN8 anticorps
  • C6H10orf2 anticorps
  • D19Ertd626e anticorps
  • IOSCA anticorps
  • MTDPS7 anticorps
  • PEO anticorps
  • PEO1 anticorps
  • PEOA3 anticorps
  • SANDO anticorps
  • SCA8 anticorps
  • Twinl anticorps

Protein level used designations for C10ORF2

uncharacterized protein LOC414487 , twinkle protein, mitochondrial , T7 gp4-like protein with intramitochondrial nucleoid localization , T7 helicase-related protein with intramitochondrial nucleoid localization , T7-like mitochondrial DNA helicase , ataxin 8 , mitochondrial twinkle protein , progressive external ophthalmoplegia 1 protein , progressive external ophthalmoplegia 1 , progressive external ophthalmoplegia 1 homolog , progressive external ophthalmoplegia 1 protein homolog

GENE ID SPECIES
414487 Xenopus laevis
710958 Macaca mulatta
56652 Homo sapiens
486845 Canis lupus familiaris
309441 Rattus norvegicus
425626 Gallus gallus
226153 Mus musculus