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Induces contraction of stomach muscle (By similarity). De plus, nous expédions Chromosome 12 Open Reading Frame 39 Kits (2) et beaucoup plus de produits pour cette protéine.
Lower circulating levels of Spexin in obese children compared with their normal-weight counterparts and the ability to discriminate obese and normal-weight groups based on Spexin concentration enabled us to suggest a potential role for this novel peptide in childhood obesity.
The results suggest that C12orf39, CSTA (Montrer CSTA Anticorps), and CALCB (Montrer CALCB Anticorps) are novel ATF4 (Montrer ATF4 Anticorps) target genes, and that C12orf39 promoter activity is activated by ATF4 (Montrer ATF4 Anticorps) through amino acid response element.
Circulating spexin levels are low in T2DM patients and negatively related to blood glucose and lipids suggesting that the peptide may play a role in glucose and lipid metabolism in T2DM.
Data from ligand-receptor interaction studies suggest that human spexin-1 and zebrafish spexin-2 activate galanin (Montrer GAL Anticorps) receptors GALR2 (Montrer GALR2 Anticorps)/GALR3 (Montrer GALR3 Anticorps) (but not GALR1 (Montrer GALR1 Anticorps)); thus spexins appear to be natural ligands for human/Xenopus/zebrafish GALR2 (Montrer GALR2 Anticorps)/GALR3 (Montrer GALR3 Anticorps).
newly identified peptides derived from the NPQ/spexin precursor contribute to CNS-mediated control of arterial blood pressure and salt and water balance and modulate nociceptive responses
Taken together, although C12ORF39 is not a secreted small peptide, it can also be secreted to play a role in the biological functions of the placenta.
Induces contraction of stomach muscle (By similarity).
, neuropeptide Q