anti-Coagulation Factor VIII (F8) Anticorps

F8 encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. De plus, nous expédions Factor VIII Kits (63) et Factor VIII Protéines (24) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
F8 14069 Q06194
F8 2157 P00451
F8 302470  
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Top anti-Factor VIII Anticorps sur anticorps-enligne.fr

Showing 10 out of 324 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit <br /> Target Name: F8 <br /> Sample Tissue: 721_B Whole Cell <br /> Lane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide <br />Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 2 µg/mL Lysate Quantity: 241 µg/laneGel Concentration: 2.12 % 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Western Blot: Factor VIII antibody (S2194) [ABIN4493381] - in extracts from HuvEc cells. Immunocytochemistry/Immunofluorescence: Factor VIII Antibody [ABIN4493381] - Factor VIII antibody was tested 1:50 in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails
Chien Lapin Inconjugué WB Western blot analysis of Factor VIII expression in HeLa (A), HepG2 (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, IHC, WB ABIN6266536 staining HuvEc cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. Western blot analysis on HuvEc cell lysate using Factor VIII Antibody,The lane on the left is treated with the antigen-specific peptide. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Souris Inconjugué ELISA Detection limit for recombinant GST tagged F8 is approximately 3ng/ml as a capture antibody. Proximity Ligation Analysis of protein-protein interactions between CALR and F8. HeLa cells were stained with anti-CALR rabbit purified polyclonal 1:1200 and anti-F8 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue). 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from HuvEc cells, using Factor VIII Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Souris Inconjugué ELISA, WB Figure 1: Western blot analysis using F8 mouse mAb against truncated Trx-F8 recombinant protein (1). Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded human Liver tissues using BHMT mouse mAb Dilution: 1:200~~1000 100 μL Connectez-vous pour afficher 10 to 11 Days
$475.29
Détails
Chien Lapin Inconjugué IF (p), IHC (p) Formalin-fixed and paraffin embedded rat tibia tissue labeled with Anti-Factor VIII (FVIII) Polyclonal Antibody (ABIN668601) , Unconjugated at 1:300, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed : Mouse C57 cells labeled with Anti- Factor VIII (FVIII) Polyclonal Antibody (ABIN668601) , Unconjugated at 1:300, followed by conjugation to the secondary antibody was Goat Anti-Rabbit IgG, PE conjugated  at 1:200 for 40 minutes at 37 °C DAPI (5 µg/mL, blue) was used to stain the cell nuclei 100 μL Connectez-vous pour afficher 3 to 7 Days
$318.45
Détails
Humain Lapin Inconjugué ELISA, IHC, WB 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails

anti-Factor VIII Anticorps mieux référencés

  1. Human Polyclonal Factor VIII Primary Antibody pour WB - ABIN3042924 : Wu, Chen, Guo, He, Hu: Effects of transforming growth factor-?2 on myocilin expression and secretion in human primary cultured trabecular meshwork cells. dans International journal of clinical and experimental pathology 2014 (PubMed)
    Show all 15 Pubmed References

  2. Dog (Canine) Polyclonal Factor VIII Primary Antibody pour IF (p), IHC (p) - ABIN668601 : Yu, Zhang, Jiang, Wang, Zhang: Astragalosides promote angiogenesis via vascular endothelial growth factor and basic fibroblast growth factor in a rat model of myocardial infarction. dans Molecular medicine reports 2015 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal Factor VIII Primary Antibody pour IF (cc), IF (p) - ABIN728000 : Zhou, Zhu, Zou, Wang: Changes in number and biological function of endothelial progenitor cells in hypertension disorder complicating pregnancy. dans Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2008 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal Factor VIII Primary Antibody pour IF (p), IHC (p) - ABIN872493 : Tang, Liu, Dong, Li, Li, Hou, Zheng, Lin, Ren: Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts. dans Inflammation 2014 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal Factor VIII Primary Antibody pour ELISA, WB - ABIN969123 : Shovlin, Sulaiman, Govani, Jackson, Begbie: Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism. dans Thrombosis and haemostasis 2007 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal Factor VIII Primary Antibody pour ICC, IF - ABIN449338 : Zhu, Liu, Miao, Qu, Chi: Enhanced plasma factor VIII activity in mice via cysteine mutation using dual vectors. dans Science China. Life sciences 2012 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal Factor VIII Primary Antibody pour ELISA, WB - ABIN966113 : Venceslá, Corral-Rodríguez, Baena, Cornet, Domènech, Baiget, Fuentes-Prior, Tizzano: Identification of 31 novel mutations in the F8 gene in Spanish hemophilia A patients: structural analysis of 20 missense mutations suggests new intermolecular binding sites. dans Blood 2008 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre Factor VIII partenaires d’interaction

Zebrafish Coagulation Factor VIII (F8) interaction partners

  1. gene is flanked by factor VII (Montrer TH Anticorps) and factor X genes; gene encodes a protein homologous to factor VII (Montrer TH Anticorps), but lacks critical residues for factor VII (Montrer TH Anticorps) activity; functions as an inhibitor of blood coagulation in biochemical assays using zebrafish or human plasmas

Mouse (Murine) Coagulation Factor VIII (F8) interaction partners

  1. CD32 blockade suppresses the FVIII-specific recall response by two ways: i) increasing apoptosis of FVIII-specific memory B-cells and ii) disturbing FVIII-specific T cell response by modulating presentation of rhFVIII to CD4(+) T cells.

  2. Type 2N von Willebrand disease variants were associated with decreased VWF (Montrer VWF Anticorps) secretion and impaired factor VIII binding/stability.

  3. Cytokine release was quantified from FVIII(-/-) splenocytes restimulated with FVIII in the absence or presence of different anti-FcgammaRIIB (CD32) Antibodies (anti-CD32 mAbs) over 6 days.

  4. results revealed localized vascular expression of FVIII and von Willebrand factor (Montrer VWF Anticorps) and identified lymphatic endothelial cell as a major cellular source of FVIII in extrahepatic tissues.

  5. the results indicate that residues in the C1 and/or C2 domains of factor VIII are implicated in immunogenic factor VIII uptake, at least in vitro Conversely, in vivo, the binding to endogenous von Willebrand factor (Montrer VWF Anticorps) masks the reducing effect of mutations in the C domains on factor VIII immunogenicity.

  6. data demonstrate that infusion of platelets containing FVIII triggers neither primary nor memory anti-FVIII immune response in FVIII(null) mice

  7. Both platelet-VWF (Montrer VWF Anticorps) and plasma-VWF (Montrer VWF Anticorps) are required for optimal platelet-derived FVIII gene therapy for hemophilia A in the presence of inhibitors.

  8. These data support the investigation of FVIII orthologs as treatment modalities in both the congenital and acquired FVIII inhibitor settings.

  9. Activatable bioengineered FIX molecules with FVIII-independent activity might be a promising tool for improving hemophilia A treatment, especially for patients with inhibitors.

  10. This study demonstrated that FVIIIa interacts with Low-density lipoprotein receptor-related protein 1 (Montrer LRP1 Anticorps) cluster III.

Human Coagulation Factor VIII (F8) interaction partners

  1. The aim of this study was to determine the F8 mutations in severe HA (sHA) patients and female carriers

  2. Human FVIII gene transfer without in vivo selection of manipulated cells can introduce immune tolerance in hemophilia A mice and this immune tolerance is CD4 (Montrer CD4 Anticorps)(+) T cell mediated.

  3. High dose of rhFVIII induces apoptosis in FVIII-specific memory B-cells but does not influence FVIII-specific T cell response.

  4. Case Report: complex recombination with deletion in the F8 and duplication in the TMLHE (Montrer TMLHE Anticorps) mediated by int22h copies during early embryogenesis in proband's mother.

  5. Report a diagnostic algorithm that can reliably identify pathogenic variants of factor 8/9 and von Willebrand factor (Montrer VWF Anticorps) and diagnose patients with hemophilia A, hemophilia B or von Willebrand disease.

  6. Each hFVIII vector was administered to FVIII knockout (KO) mice at a dose of 10(10) genome copies (GC) per mouse. Criteria for distinguishing the performance of the different enhancer/promoter combinations were established prior to the initiation of the studies.

  7. Relevance of ethnic differences in factor XIII (Montrer UGDH Anticorps) activity on laboratory reference ranges.

  8. analysis of co-existing variants in both F8 and PTGS-1 (Montrer PTGS1 Anticorps) genes in a three-generation pedigree of hemophilia A

  9. FVIII endocytosis is driven by interaction with LRP1 (Montrer LRP1 Anticorps)

  10. A coagulation initiating pathway is revealed in which the TF-FVIIa-nascent FXa (Montrer F10 Anticorps) complex activates FVIII apart from thrombin (Montrer F2 Anticorps) feedback.

Pig (Porcine) Coagulation Factor VIII (F8) interaction partners

  1. It was concluded that VEGF (Montrer VEGFA Anticorps) and factor VIII are important growth factors associated with fetal development in pigs and are identified in all uterine segments.

  2. thrombin (Montrer F2 Anticorps) stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (Montrer UGDH Anticorps) and by receptor-mediated up-regulation of factor XIII (Montrer UGDH Anticorps) synthesis

  3. cupredoxin-like A1 subdomains in fVIII contain inter-species differences that are a result of selective pressure on the dissociation rate constant

Cow (Bovine) Coagulation Factor VIII (F8) interaction partners

  1. Factor VIIIc (Montrer COX7A2 Anticorps) is responsible for tissue invasion during tumor progression.

Factor VIII (F8) profil antigène

Profil protéine

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Gene names and symbols associated with F8

  • coagulation factor VIIi (f7i) anticorps
  • coagulation factor VIII (F8) anticorps
  • coagulation factor VIII, procoagulant component (F8) anticorps
  • AHF anticorps
  • Cf-8 anticorps
  • Cf8 anticorps
  • DXS1253E anticorps
  • F8B anticorps
  • F8C anticorps
  • fb61d02 anticorps
  • FVIII anticorps
  • HEMA anticorps
  • wu:fb61d02 anticorps

Protein level used designations for F8

Factor VIII , procoagulant component , antihemophilic factor , coagulation factor VIII , coagulation factor VIIIc , factor VIII F8B , coagulation factor VIII, procoagulant component (hemophilia A) , factor VIII , coagulation co-factor

GENE ID SPECIES
282671 Danio rerio
14069 Mus musculus
2157 Homo sapiens
397339 Sus scrofa
403875 Canis lupus familiaris
100271720 Bos taurus
100303761 Oryctolagus cuniculus
302470 Rattus norvegicus
100359363 Ovis aries
422199 Gallus gallus
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