Colony Stimulating Factor 3 Receptor (Granulocyte) Protéines (CSF3R)

The protein encoded by CSF3R is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. De plus, nous expédions CSF3R Anticorps (193) et CSF3R Kits (49) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
CSF3R 1441 Q99062
CSF3R 12986 P40223
CSF3R 298518  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top CSF3R Protéines sur anticorps-enligne.fr

Showing 10 out of 26 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Human Cells Humain Fc Tag 100 μg Connectez-vous pour afficher 14 to 16 Days
$382.80
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
HEK-293 Cells Humain His tag 100 μg Connectez-vous pour afficher 2 to 3 Days
$615.00
Détails
Escherichia coli (E. coli) Souris His tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$672.00
Détails
Escherichia coli (E. coli) Rat His tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$714.00
Détails
Escherichia coli (E. coli) Humain GST tag Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-620) protein (GST tag) 50 μg Connectez-vous pour afficher 13 to 16 Days
$242.00
Détails
HEK-293 Cells Humain His tag 100 μg Connectez-vous pour afficher 2 to 3 Days
$275.00
Détails
HEK-293 Cells Humain Fc Tag 200 μg Connectez-vous pour afficher 2 to 3 Days
$319.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails

CSF3R Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , , ,
, , , ,
Mouse (Murine) ,
,
Rat (Rattus)

CSF3R Protéines mieux référencés

  1. Human CSF3R Protein expressed in HEK-293 Cells - ABIN2181144 : Ko, Chandra, Ouyang, Kwon, Karande, Han: Nanofluidic device for continuous multiparameter quality assurance of biologics. dans Nature nanotechnology 2017 (PubMed)

  2. Human CSF3R Protein expressed in Human Cells - ABIN2002378 : Germeshausen, Ballmaier, Welte: Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: Results of a long-term survey. dans Blood 2006 (PubMed)
    Show all 5 Pubmed References

Plus protéines pour Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) partenaires d'interaction

Human Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. Expression and role of granulocyte macrophage colony-stimulating factor receptor (Montrer CSF2RA Protéines) (GM-CSFR (Montrer CSF2RA Protéines)) and granulocyte colony-stimulating factor receptor (G-CSFR) on Ph-positive acute B lymphoblastic leukemia.

  2. we report here for the first time changes in the allele frequencies of CSF3R-T618I and SETBP1 (Montrer SETBP1 Protéines)-G870S with response to ruxolitnib as well as insights into the clonal evolution of CNL under selective pressure from ruxolitinib.

  3. CSF3R genetic polymorphism occurred more frequently in the individuals with Septic Arthroplasty failure - Periprosthetic Joint Infection.

  4. G-CSF-R is C-mannosylated at W318 and that this C-mannosylation has role(s) for myeloid cell differentiation through regulating downstream signaling.

  5. CSF3R mutations co-occur with CEBPA (Montrer CEBPA Protéines) mutations in pediatric acute myeloid leukemia (Montrer BCL11A Protéines).

  6. we have expanded the region of the CSF3R cytoplasmic domain in which truncation or missense mutations exhibit leukemogenic capacity, which will be useful for evaluating the relevance of CSF3R mutations in patients and helpful in defining targeted therapy strategies.

  7. our data demonstrates that E6AP (Montrer ube3a Protéines) facilitates ubiquitination and subsequent degradation of G-CSFR leading to attenuation of its downstream signaling and inhibition of granulocytic differentiation.

  8. study aimed to identity and characterize novel CSF3R extracellular missense mutations from exome sequencing of leukemia patients; results show the structural and functional importance of conserved extracellular cysteine pairs in CSF3R

  9. a central role of enhanced Mapk (Montrer MAPK1 Protéines) signaling in CSF3R-induced leukemia.

  10. CSF3R T618I mutation is associated with Chronic neutrophilic leukemia.

Mouse (Murine) Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. Anti-G-CSF receptor rapidly halted the progression of established disease in collagen Ab-induced arthritis in mice. Neutrophil accumulation in joints was inhibited, without rendering animals neutropenic, suggesting an effect of G-CSF receptor blockade on neutrophil homing to inflammatory sites.

  2. this study shows that dorsal root ganglion neurons cultured in G-CSF (Montrer CSF3 Protéines) failed to respond to G-CSF (Montrer CSF3 Protéines) in vitro, and Csf3r gene expression could not be detected in dorsal root ganglion neurons by single-cell RT-PCR

  3. Thr (Montrer TRH Protéines)-615 and Thr (Montrer TRH Protéines)-618 sites of membrane-proximal mutations are part of an O-linked glycosylation cluster. Mutation at these sites prevents O-glycosylation of CSF3R and increases receptor dimerization.

  4. Fbw7 (Montrer FBXW7 Protéines) together with GSK3beta negatively regulates G-CSFR expression and its downstream signaling.

  5. G-CSFR signaling interacts with retinoic acid receptors in the regulation of myeloid differentiation

  6. Expression of truncated G-CSFR significantly shortens the latency of AML (Montrer RUNX1 Protéines) in a G-CSF (Montrer CSF3 Protéines)-dependent fashion and it is associated with a distinct AML (Montrer RUNX1 Protéines) presentation characterized by higher blast counts and more severe myelosuppression.

  7. G-CSFR signals in bone marrow monocytic cells inhibit the production of trophic factors required for osteoblast lineage cell maintenance, ultimately leading to hematopoietic stem and progenitor cell mobilization.

  8. Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF (Montrer CSF3 Protéines)-induced expansion of myeloid progenitor cells.

  9. murine granulocyte colony-stimulating factor receptor binds to a low molecular weight ligand

  10. Mice with truncated G-CSF (Montrer CSF3 Protéines) receptors have neutropenia, susceptibility to infection, and bone marrow maturation arrest similar to severe congenital neutropenic humans, suggesting a role of receptor truncation mutations in SCN (Montrer SRI Protéines) pathology.

Zebrafish Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. GCSF (Montrer CSF3 Protéines)/GCSFR is a conserved signaling system for facilitating the production of multiple myeloid cell lineages, as well as for early myeloid cell migration.

Profil protéine CSF3R

Profil protéine

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

Gene names and symbols associated with CSF3R

  • colony stimulating factor 3 receptor (CSF3R)
  • colony stimulating factor 3 receptor (granulocyte) (Csf3r)
  • colony stimulating factor 3 receptor (Csf3r)
  • colony stimulating factor 3 receptor (granulocyte) (csf3r)
  • colony stimulating factor 3 receptor L homeolog (csf3r.L)
  • granulocyte colony-stimulating factor receptor (LOC100433338)
  • cd114 Protéine
  • CSF3R Protéine
  • Csfgr Protéine
  • G-CSF-R Protéine
  • G-CSFR Protéine
  • gcsfr Protéine

Protein level used designations for CSF3R

CD114 antigen , G-CSF receptor , G-CSF-R , granulocyte colony-stimulating factor receptor , colony stimulating factor 3 receptor (granulocyte) , granulocyte stimulating factor receptor , granulocyte colony-stimulating factor receptor-like

GENE ID SPECIES
1441 Homo sapiens
12986 Mus musculus
100069253 Equus caballus
298518 Rattus norvegicus
100134935 Danio rerio
446770 Xenopus laevis
419620 Gallus gallus
607605 Canis lupus familiaris
456756 Pan troglodytes
713485 Macaca mulatta
100433338 Pongo abelii
100464681 Ailuropoda melanoleuca
101118070 Ovis aries
100717194 Cavia porcellus
511511 Bos taurus
Fournisseurs de qualité sélectionnés pour CSF3R Protéines (CSF3R)
Avez-vous cherché autre chose?