Contactin Associated Protein-Like 2 (CNTNAP2) Kits ELISA

CNTNAP2 encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. De plus, nous expédions CNTNAP2 Anticorps (76) et CNTNAP2 Protéines (6) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CNTNAP2 26047 Q9UHC6
Anti-Souris CNTNAP2 CNTNAP2 66797 Q9CPW0
Anti-Rat CNTNAP2 CNTNAP2 500105  
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Top CNTNAP2 Kits ELISA sur anticorps-enligne.fr

Showing 6 out of 13 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.059 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
$736.84
Détails
Poulet 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$731.99
Détails
Porc 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$731.99
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Lapin 37.5 pg/mL 62.5 pg/mL - 4000 pg/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$731.99
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Cobaye 46.875 pg/mL 78.125 pg/mL - 5000 pg/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$731.99
Détails
Singe 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$731.99
Détails

Plus Kits ELISA pour CNTNAP2 partenaires d'interaction

Human Contactin Associated Protein-Like 2 (CNTNAP2) interaction partners

  1. This study evaluated a possible association between ASD (Montrer ARSD Kits ELISA) and the presence of five single nucleotide polymorph-isms (rs7794745, rs10500171, rs2710105,rs2710102, and rs2538989 ) in CNTNAP2in the Korean population. The genetic variants in CNTNAP2 do not play a role in ASD (Montrer ARSD Kits ELISA) affection possibility in this study, but evidence suggests that one SNP(rs10500171) might be associated with sociality-relatedphenotypes in Koreans

  2. In utero CASPR2-IgG exposed neonates achieved milestones similarly to healthy control-IgG exposed but, when adult, the CASPR2-IgG exposed progeny showed marked social interaction deficits, abnormally located glutamatergic neurons in layers V-VI of the somatosensory cortex, a 16% increase in activated microglia, and a 15-52% decrease in glutamatergic synapses in layers of the prefrontal and somatosensory cortices.

  3. the selective distribution of Caspr2 and TAG-1 (Montrer CNTN2 Kits ELISA) may be regulated, allowing them to modulate the strategic function of the Kv1 (Montrer KCNA5 Kits ELISA) complex along axons

  4. The clinical phenotypes of anti-LGI1 (Montrer LGI1 Kits ELISA) encephalitis and anti-Caspr2 encephalitis have been described in more detail including data on treatment and long-term follow-up. Lumping patients with anti-LGI1 (Montrer LGI1 Kits ELISA), anti-Caspr2 antibodies or lacking both, should be considered obsolete--{REVIEW}

  5. Subjects with greater left dorsolateral prefrontal cortex (DLPFC) surface area had better cognitive performance. Importantly, the left DLPFC surface area mediated the association between the CNTNAP2 rs4726946 genotype and cognitive performance. This study provides the first evidence for associations among the CNTNAP2 gene, left DLPFC structure, and cognitive control.

  6. associations of a common CNTNAP2 polymorphism (rs7794745) with variation in grey matter in a region in the dorsal visual stream

  7. Bi-allelic aberrations (mutations and copy number variants) in CNTNAP2 in eight individuals with intellectual disability and epilepsy were reported.

  8. Older age is a strong predictor of CNS involvement in patients seropositive for CASPR2-IgG or LGI1 (Montrer LGI1 Kits ELISA)-IgG. Pain, peripheral manifestations, and stereotypic paroxysmal dizziness spells are common with LGI1 (Montrer LGI1 Kits ELISA)-IgG.

  9. Caspr2 antibodies associate with a treatable disorder that predominantly affects elderly men. The resulting syndrome may vary among patients but it usually includes a set of well-established symptoms.

  10. The molecular shape and dimensions of CNTNAP2 place constraints on how CNTNAP2 integrates in the cleft of axo-glial and neuronal contact sites and how it functions as an organizing and adhesive molecule.

Mouse (Murine) Contactin Associated Protein-Like 2 (CNTNAP2) interaction partners

  1. This study demonstrated an age-dependent effect of Cntnap2 deletion on both tonic and phasic inhibition in layer 2/3 pyramidal cells in the visual cortex.

  2. native medial prefrontal cortex parvalbumin (Montrer PVALB Kits ELISA) neuronal activity differed between CNTNAP2 knockout and wild-type mice.

  3. Caspr2/Caspr1 (Montrer CNTNAP1 Kits ELISA) double mutants results in muscle fiber degeneration accompanied by mitochondrial dysfunction.

  4. Cntnap2 KO rats exhibited severe motor seizures, hyperactivity, and increased consolidation of wakefulness and REM sleep. By contrast, Cntnap2 KO mice demonstrated absence seizure-like events, hypoactivity, and wake fragmentation.

  5. After middle cerebral artery occlusion mice demonstrate profoundly impaired socially evoked USVs. In addition, there is suppression of the language-associated transcription factor,contactin-associated protein 2 (Cntnap2).

  6. Olfaction-based behavioral tests revealed that mice lacking Caspr2 exhibit abnormal response to sensory stimuli and lack preference for novel odors.

  7. Mice with the Cntnap2 genetic mutation showed a dissociation of auditory-processing abilities

  8. Study reports behavioral characterization of mouse models of autism with null mutation in Cntnap2 gene. It shows hyperactivity, mild gait phenotype and reduced vocalizations among others.

  9. new dendritic spines in mice lacking CNTNAP2 were formed at normal rates, but failed to stabilize. Notably, rates of spine elimination were unaltered, suggesting a specific role for CNTNAP2 in stabilizing new synaptic circuitry

  10. Cntnap2 deletion selectively impairs perisomatic hippocampal inhibition while sparing excitation provide additional support for synaptic dysfunction as a common mechanism underlying autism spectrum disorders

CNTNAP2 profil antigène

Antigen Summary

This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.

Gene names and symbols associated with CNTNAP2

  • contactin associated protein like 2 (CNTNAP2) anticorps
  • contactin associated protein-like 2 (Cntnap2) anticorps
  • contactin associated protein-like 2 (CNTNAP2) anticorps
  • contactin associated protein like 2b (cntnap2b) anticorps
  • contactin associated protein like 2 (cntnap2) anticorps
  • contactin associated protein like 2 (Cntnap2) anticorps
  • 5430425M22Rik anticorps
  • AUTS15 anticorps
  • CASPR anticorps
  • Caspr2 anticorps
  • CDFE anticorps
  • MGC145769 anticorps
  • MGC147944 anticorps
  • MGC147981 anticorps
  • mKIAA0868 anticorps
  • NRXN4 anticorps
  • PTHSL1 anticorps

Protein level used designations for CNTNAP2

cell recognition molecule Caspr2 , contactin-associated protein-like 2 , homolog of Drosophila neurexin IV , contactin associated protein-like 2 , novel protein similar to H.sapiens contactin associated protein , contactin associated protein 2 , contactin-associated protein-like 2-like

GENE ID SPECIES
26047 Homo sapiens
66797 Mus musculus
463819 Pan troglodytes
516395 Bos taurus
563345 Danio rerio
574172 Macaca mulatta
780189 Xenopus (Silurana) tropicalis
100174321 Pongo abelii
100013863 Monodelphis domestica
100060296 Equus caballus
100073864 Ornithorhynchus anatinus
100223892 Taeniopygia guttata
100354524 Oryctolagus cuniculus
100397041 Callithrix jacchus
100607262 Nomascus leucogenys
500105 Rattus norvegicus
100717858 Cavia porcellus
100687859 Canis lupus familiaris
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