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Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. De plus, nous expédions CPNE1 Protéines (15) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal CPNE1 Primary Antibody pour ELISA, WB - ABIN4300257
Zhang, Gao, Duan, He, Sun, Jiang, Duan, Zhong, Ge: Upregulation of Copine1 in trabecular meshwork cells of POAG patients: a membrane proteomics approach. dans Molecular vision 2008
Human Polyclonal CPNE1 Primary Antibody pour WB - ABIN2668817
Ramsey, Yeung, Stoddard, Li, Creutz, Mayo: Copine-I represses NF-kappaB transcription by endoproteolysis of p65. dans Oncogene 2008
Collectively, our findings suggest that JAB1 (Montrer COPS5 Anticorps) activates the neuronal differentiation ability of CPNE1 through the binding of C2A domain in CPNE1 with MPN (Montrer PRSS27 Anticorps) domain in JAB1 (Montrer COPS5 Anticorps).
Copine I regulates tumour necrosis factor-alpha (Montrer TNF Anticorps) receptor signaling pathways.
Copine1 is upregulated in plasma membranes of TM cells in individuals with primary open-angle glaucoma.
CPNE1 shares a promoter and 5'UTR (Montrer UTS2R Anticorps) exons with RBM12 (Montrer RBM12 Anticorps). This genomic structure is conserved among multiple species.
These data demonstrate that CPNE1 plays a key role in the regulation of neural stem cell functions through the activation of AKT (Montrer AKT1 Anticorps)-mTOR (Montrer FRAP1 Anticorps) signaling pathway during brain development.
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins.
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