anti-Cyclin-Dependent Kinase 14 (CDK14) Anticorps

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. De plus, nous expédions CDK14 Protéines (13) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CDK14 5218 O94921
CDK14 18647 O35495
CDK14 362316  
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Top anti-CDK14 Anticorps sur anticorps-enligne.fr

Showing 10 out of 85 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Chien Lapin Inconjugué WB WB Suggested Anti-Cdk14 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Pancreas 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of PFTK1 / CDK14  Antibody in mouse liver tissue lysates (35ug/lane). PFTK1 (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué EIA, IHC (p) Formalin-fixed and paraffin-embedded human testis tissue reacted with PFTK1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of PFTK1 Antibody (N-term P82) in mouse cerebellum tissue lysates (35ug/lane). PFTK1 (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of lysate from human brain tissue lysate, using PFTK1 Antibody (N-term P82) at 1:1000 at each lane. PFTK1 Antibody (N-term P82) (RB18842) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PFTK1 Antibody (N-term P82) for immunohistochemistry. 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué WB Western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Mdetected the Mouse Cdk14 protein (arrow). 400 μL 2 to 3 Days
$515.63
Détails
Chien Lapin Inconjugué WB   100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué IF, IHC (p) Immunofluorescent staining of human cell line U-2 OS with PFTK1 polyclonal antibody  shows positivity in nucleus and cytoplasm. Antibody staining is shown in green. Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebral cortex with PFTK1 polyclonal antibody  shows cytoplasmic positivity in neuronal cells. 100 μL 11 to 12 Days
$577.33
Détails
Humain Souris Inconjugué ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL 11 to 12 Days
$305.71
Détails
Humain Souris Inconjugué IF, WB Western Blot analysis of PFTK1 expression in transfected 293T cell line by PFTK1 MaxPab polyclonal antibody.Lane 1: PFTK1 transfected lysate(49.61 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to PFTK1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg 11 to 12 Days
$440.00
Détails

anti-CDK14 Anticorps mieux référencés

  1. Human Polyclonal CDK14 Primary Antibody pour IHC (fro), ELISA - ABIN543911 : Nagase, Ishikawa, Suyama, Kikuno, Hirosawa, Miyajima, Tanaka, Kotani, Nomura, Ohara: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. dans DNA research : an international journal for rapid publication of reports on genes and genomes 1999 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal CDK14 Primary Antibody pour ICC, IF - ABIN4345007 : Miyagaki, Yamasaki, Miyata, Takahashi, Kurokawa, Nakajima, Takiguchi, Fujiwara, Ishii, Tanaka, Mori, Doki: Overexpression of PFTK1 predicts resistance to chemotherapy in patients with oesophageal squamous cell carcinoma. dans British journal of cancer 2012 (PubMed)

Plus d’anticorps contre CDK14 partenaires d’interaction

Human Cyclin-Dependent Kinase 14 (CDK14) interaction partners

  1. the ectopic overexpression of SNHG15 contribute to the non-small cell lung cancer tumorigenesis by regulating CDK14 protein via sponging miR-486.

  2. Data suggest the risk-associated single nucleotide polymorphism (SNP) rs10272859 of cyclin dependent kinase 14 (CDK14) gene at 7q21.13 conferring both susceptibility and prognosis to HBV-related hepatocellular carcinoma (HCC).

  3. CDK14 overexpression reversed the suppressive effects of miR-542-3p in ovarian cancer cells.

  4. CDK14 was validated to be the target protein the miR-139.

  5. OIP5-AS1 acts as a miR-223 'sponge' to trigger CDK14 expression to promote osteosarcoma tumorigenesis.

  6. knockdown of E2F5 and PFTK1 mimicked the tumor-suppressive effects of miR-1-3p overexpression on PCa progression. Conversely, concomitant knockdown of miR-1-3p and E2F5 and PFTK1 substantially reversed the inhibitory effects of either E2F5 or PFTK1 silencing alone.

  7. MiR-613 and CDK14 may serve as potential therapeutic targets for the treatment of glioma.

  8. CDK14 mediated miR-1202 to exert its anti-tumor effects.

  9. CDK14 expression was closely associated with poor prognosis and overall survival of Osteosarcoma patients. miR-216a inhibits CDK14 expression by binding to the 3'-untranslated region of CDK14.

  10. PFTK1 expression is significantly higher in CRC tissues compared with matched adjacent noncancerous colorectal tissues. The associations between PFTK1 expression and clinicopathological characters, and PFTK1 expression and the OS rate following resection suggested that PFTK1 may represent a novel biomarker of poor prognosis in CRC

  11. Results show that CDK14 and DYRK2 expression were inversely correlated in human breast cancer tissues and identified CDK14 as a target of DYRK2.

  12. miR-455 inhibits breast cancer cell proliferation through targeting CDK14

  13. findings revealed an unrecognized role of Caprin-2 in facilitating LRP5/6 constitutive phosphorylation at G2/M through forming a quaternary complex with CDK14, Cyclin Y, and LRP5/6.

  14. these results suggest that knockdown of PFTK1 inhibited the proliferation and invasion of colon cancer cells as well as the EMT progress by suppressing the Sonic hedgehog signaling pathway.

  15. we report that PFTK1 downregulation might inhibit the proliferation and invasion of NSCLC cells by suppressing the Wnt/beta-catenin signaling pathway.

  16. The expression level of PFTK1 was correlated with tumor grade, FIGO stage, lymph node metastasis of EOC patients as well as poor prognosis.

  17. Knockdown of PFTK1 inhibited the proliferation and invasion of pancreatic cancer cells as well as the EMT progress by suppressing the PI3K/Akt signaling pathway.

  18. PFTK1 overexpression promoted proliferation, migration and invasion of gastric cancer cells, while PFTK1 knockdown led to the opposite results.

  19. Knockdown of PFTK1 increases E-cadherin expression, decreases vimentin expression and inhibits migration of glioma cells.

  20. Up-regulated PFTK1 might promote breast cancer progression.

Mouse (Murine) Cyclin-Dependent Kinase 14 (CDK14) interaction partners

  1. Cigarette smoke down regulates CDK14 levels and impairs Wnt signaling.

  2. may be a key regulator for thyrotropin-releasing hormone (TRH) action in the cerebellum through the NO-cGMP pathway

CDK14 profil antigène

Profil protéine

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.

Gene names and symbols associated with CDK14

  • cyclin dependent kinase 14 (CDK14) anticorps
  • cyclin-dependent kinase 14 (Cdk14) anticorps
  • cyclin-dependent kinase 14 L homeolog (cdk14.L) anticorps
  • mKIAA0834 anticorps
  • pftaire1 anticorps
  • pftk1 anticorps

Protein level used designations for CDK14

PFTAIRE protein kinase 1 , cell division protein kinase 14 , hPFTAIRE1 , serine/threonine-protein kinase PFTAIRE-1 , Cell division protein kinase 14

GENE ID SPECIES
463522 Pan troglodytes
703442 Macaca mulatta
100137460 Papio anubis
100173505 Pongo abelii
5218 Homo sapiens
18647 Mus musculus
362316 Rattus norvegicus
100328634 Oryctolagus cuniculus
420546 Gallus gallus
475223 Canis lupus familiaris
100515962 Sus scrofa
784403 Bos taurus
101424147 Dasypus novemcinctus
100391008 Callithrix jacchus
444781 Xenopus laevis
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