anti-Cysteine and Glycine-Rich Protein 3 (CSRP3) Anticorps

CSRP3 encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. De plus, nous expédions CSRP3 Protéines (8) et CSRP3 Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CSRP3 8048 P50461
CSRP3 13009 P50462
CSRP3 117505 P50463
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Top anti-CSRP3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 87 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-CSRP3 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human heart Host:  Rabbit  Target Name:  CSRP3  Sample Tissue:  Human HCT116 Whole Cell  Antibody Dilution:  1ug/ml 100 μL 2 to 3 Days
$319.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-CSRP3 Antibody Titration:  0.125ug/ml  Positive Control:  Human muscle 100 μL 2 to 3 Days
$289.00
Détails
Humain Chèvre Inconjugué ELISA, IHC, WB ABIN334380 (0.01µg/ml) staining of Rat Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN334380 (0.01µg/ml) staining of Human (A), Mouse (B) and Rat (C) Heart lysate (35µg protein in RIPA buffer). Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.84
Détails
Roussette (Chauve-souris) Chèvre Inconjugué ELISA, IHC, IHC (p), WB Anti-CSRP3 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962646 concentration 41396 ug/ml. Anti-CSRP3 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962646 concentration 41396 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL 11 to 14 Days
$493.17
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cell lines, using CSRP3 antibody (ABIN5973946) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded mouse heart using CSRP3 Antibody (ABIN5973946) at dilution of 1/100 (40x lens). 100 μL 11 to 16 Days
$426.40
Détails
Humain Souris Inconjugué IF, RNAi, ELISA, WB Western Blot analysis of CSRP3 expression in transfected 293T cell line by CSRP3 monoclonal antibody (M03), clone 6D2.Lane 1: CSRP3 transfected lysate(20.969 KDa).Lane 2: Non-transfected lysate. Western blot analysis of CSRP3 over-expressed 293 cell line, cotransfected with CSRP3 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with CSRP3 monoclonal antibody (M03), clone 6D2. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué WB Western blot analysis in NCI-H460 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Détails
Humain Poulet Inconjugué WB 0.05 mg 2 to 3 Days
$515.63
Détails

anti-CSRP3 Anticorps mieux référencés

  1. Human Polyclonal CSRP3 Primary Antibody pour ELISA, ICC - ABIN451632 : Zheng, Wen, Han: hhLIM is a novel F-actin binding protein involved in actin cytoskeleton remodeling. dans The FEBS journal 2008 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal CSRP3 Primary Antibody pour WB - ABIN2778310 : Geier, Perrot, Ozcelik, Binner, Counsell, Hoffmann, Pilz, Martiniak, Gehmlich, van der Ven, Fürst, Vornwald, von Hodenberg, Nürnberg, Scheffold, Dietz, Osterziel: Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy. dans Circulation 2003 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre CSRP3 partenaires d’interaction

Human Cysteine and Glycine-Rich Protein 3 (CSRP3) interaction partners

  1. Previous results along with the newly identified homozygous CSRP3 truncating variants in two unrelated hypertrophic cardiomyopathy (HCM) patients suggest that the association of CSRP3 as a validated HCM-causing gene require additional studies and those CSRP3 variants could result in HCM with an autosomal recessive inheritance rather than with an autosomal dominant transmission as usually reported on HCM.

  2. MLP contributes to the maintenance of cardiomyocyte cytoarchitecture by a mechanism involving its self-association and actin filament cross-linking.

  3. study reports the discovery of an alternative splice variant of muscle lim protein encoded by the CSRP3 gene, designated as MLP-b, showing distinct expression in neuromuscular disease and direct roles in actin dynamics and muscle differentiation

  4. KLF5 reverses hhLIM function from anti-proliferation to pro-proliferation through its interaction with hhLIM on the cyclin E promoter.

  5. The CSRP3-W4R mutation causes cardiomyopathy and heart failure in patients and engineered knock-in animals.

  6. CSRP3 is involved in cardiac mechanosensory processes, is localized to the sarcomeric Z-disc and human mutations cause cardiomyopathy(DCM)and heart failure.

  7. Mutations in the CRP3/MLP gene can cause hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM).

  8. CSRP3, MUSTN1, SIX1, and FBXO32 expression changes in response to lengthening and shortening contractions in human muscle

  9. A myocardial actin-binding protein that increases actin cytoskeleton stability by promoting bundling of actin filaments.

  10. These findings suggest that hhLIM is a typical LIM family member with powerful transcription activation.

  11. Study used linkage analysis and identified a CSRP3 missense mutation in a large German family affected by hypertrophic cardiomyopathy.

  12. CSRP3 mutation was found involved in hypertrophic cardiomyopathy.

  13. The structure of both LIM domains of human MLP by nuclear magnetic resonance spectroscopy.

  14. CRP3/MLP is primarily expressed in arterial smooth muscle cells and that stretch is the main stimulus for CRP3/MLP induction in veins exposed to arterial haemodynamic conditions.

  15. Complete chemical shift assignment was achieved for the first LIM domain and for most of the second domain, the N-terminal and C-terminal linker and part of the intervening linker.

  16. MLP binds directly to CFL2 in human cardiac and skeletal muscles.

Mouse (Murine) Cysteine and Glycine-Rich Protein 3 (CSRP3) interaction partners

  1. our cellular experiments suggest that protein depletion and proteasomal overload also play a role in other HCM-causing CSPR3 mutations that we investigated, indicating that reduced levels of functional MLP may be a common mechanism for HCM-causing CSPR3 mutations.

  2. we identify a novel role for Csrp3 expression in skeletal muscle in the development of obesity-induced insulin resistance

  3. Ablation of MLP protein (and MYBPC3) protected mice from developing the dilated cardiomyopathy phenotype.

  4. Cardiac overexpression of muscle LIM protein does not modulate the heart's response to various forms of pathological stress.

  5. Loss of MLP leads to dilated cardiomyopathy and hearts of surviving MLP knockout mice show transient changes of intracellular calcium handling.

  6. Report a common MLP (muscle LIM protein) variant associated with a hypertrophic cardiomyopathy and heart failure phenotype, and skeletal muscle pathology.

  7. Reduced MLP-calcineurin signaling predisposes to adverse remodeling after myocardial infarct.

  8. results indicate that the progression to heart failure in the MLPKO model may be driven by diastolic myocardial dysfunction and abnormal passive properties rather than systolic dysfunction

  9. This detailed physiological characterization during a phase of rapid anatomical remodeling suggests that systolic function in the MLP(-/-) mice may temporarily improve as a result of alterations in chamber compliance, which are mediated by dilatation.

  10. Mice with knockout of muscle-LIM protein exhibit prolongation of atrial and ventricular conduction and an increased ventricular vulnerability.

  11. MLP binds directly to CFL2 in human cardiac and skeletal muscles.

Cow (Bovine) Cysteine and Glycine-Rich Protein 3 (CSRP3) interaction partners

  1. data support the high potential of the CSRP3 as a marker gene for the improvement of growth performance and carcass traits in selection programs

Pig (Porcine) Cysteine and Glycine-Rich Protein 3 (CSRP3) interaction partners

  1. CSRP3 coding gene from porcine muscle was isolated and characterized and Phylogenic analyses demonstrated that CSRP3 diverged first and is distinguished from two other members, CSRP1 and CSRP2.

Xenopus laevis Cysteine and Glycine-Rich Protein 3 (CSRP3) interaction partners

  1. is only expressed in the differentiated heart during early development and is expressed in a subset of other striated muscles during later stages

CSRP3 profil antigène

Profil protéine

This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.

Gene names and symbols associated with CSRP3

  • cysteine and glycine rich protein 3 (CSRP3) anticorps
  • cysteine and glycine-rich protein 3 (Csrp3) anticorps
  • cysteine and glycine rich protein 3 (Csrp3) anticorps
  • cysteine and glycine rich protein 3 (csrp3) anticorps
  • cysteine and glycine-rich protein 3 (cardiac LIM protein) (csrp3) anticorps
  • cysteine and glycine rich protein 3 L homeolog (csrp3.L) anticorps
  • CLP anticorps
  • CMD1M anticorps
  • CMH12 anticorps
  • CRP3 anticorps
  • CSRP3 anticorps
  • csrp3-a anticorps
  • LMO4 anticorps
  • MLP anticorps
  • MMLP anticorps
  • zgc:103468 anticorps

Protein level used designations for CSRP3

LIM domain only 4 , cardiac LIM domain protein , cysteine and glycine-rich protein 3 , muscle LIM protein , LIM domain protein, cardiac , cardiac LIM protein , cysteine-rich protein 3 , CRP3 , cysteine- and glycine-rich protein 3 , Cysteine and glycine-rich protein 3 , Muscle LIM protein , csrp3b , cysteine and glycine-rich protein 3 (cardiac LIM protein)

GENE ID SPECIES
8048 Homo sapiens
13009 Mus musculus
117505 Rattus norvegicus
540407 Bos taurus
610946 Canis lupus familiaris
100196456 Salmo salar
100337687 Sus scrofa
422979 Gallus gallus
450005 Danio rerio
473442 Pan troglodytes
702466 Macaca mulatta
100229240 Taeniopygia guttata
373825 Xenopus laevis
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