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CYP4B1 encodes a member of the cytochrome P450 superfamily of enzymes. De plus, nous expédions Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 Protéines (5) et Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 Kits (2) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 48 products:
Human Polyclonal CYP4B1 Primary Antibody pour IHC, IHC (p) - ABIN4301775
Fischer, Goss, Scheetz, Wohlford-Lenane, Snyder, McCray: Differential gene expression in human conducting airway surface epithelia and submucosal glands. dans American journal of respiratory cell and molecular biology 2009
P450 (Montrer POR Anticorps) 4B1 exhibits structural adaptations for omega-hydroxylation that include changes in the conformation of the heme and changes in a highly conserved helix I motif that is associated with selective oxygenation of unactivated primary C-H bonds.
A co-crystal structure of the rabbit family 4 enzyme CYP4B1 with its substrate octane reveals that the propensity for omega-hydroxylation is orchestrated by active-site sterics, partially mediated by an unusual heme-polypeptide ester bond.
spectral binding affinities and oxidative metabolism of the furan analogs by the purified recombinant CYP4B1 variants were analyzed: the naturally occurring perilla ketone was found to be the tightest binder to CYP4B1, but also the analog that was most extensively metabolized by oxidative processes to numerous non-reactive reaction products.
A proline residue in the meander region at position 427 in human CYP4B1 and 422 in rabbit CYP4B1 is important for protein stability and rescues the 4-ipomeanol bioactivation.
results strongly implicate the corneal CYP4B1 as a component of the inflammatory and neovascular cascade initiated by injury and further suggest that CYP4B1-12-HETrE is a proximal regulator of VEGF (Montrer VEGFA Anticorps) expression
the Ser207 insertion does not rescue the P450 (Montrer CYP2B6 Anticorps) functional activity of human CYP4B1 that has been lost during evolution.
Single nucleotide polymorphisms of CYP2C8,CYP2E1 and CYP4B1 are associated with susceptibility to gout in ethnic Han males population.
CYP4B1 is a senescene-associated gene in normal human oral keratinocytes.
Results demostrated an increased risk of bladder cancer associated with the CYP4B1*1/*2 and *2/*2 genotypes.
Detected by polymerase chain reaction in prostate tissue.
Data show that the 5' flanking region of the Cyp4b1 gene exhibits promoter activity when expressed in different cell lines and that a 98-truncated fragment represents the minimal sequence required for basal transcription.
Increased CYP4B1 mRNA is associated with the inhibition of dextran sulfate sodium-induced colitis by caffeic acid in mice.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens\; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene.
cytochrome P450 4B1
, CYP4B1 isoform
, P450-isozyme 5
, cytochrome P450 isozyme 5
, cytochrome P450, family 4, subfamily B, polypeptide 1
, cytochrome P450 XL-304
, cytochrome P450, subfamily IVB, polypeptide 1
, cytochrome P450-HP
, microsomal monooxygenase
, cytochrome P450, subfamily IV B, polypeptide 1
, P450 L-2
, cytochrome P450 L-2
, cytochrome P450, subfamily 4B, polypeptide 1