anti-Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1) Anticorps

Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. De plus, nous expédions CYP8B1 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CYP8B1 81924  
CYP8B1 1582 Q9UNU6
CYP8B1 13124 O88962
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Top anti-CYP8B1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 41 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué WB WB Suggested Anti-CYP8B1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-CYP8B1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of Cytochrome P450 8B1 expression in K562 (A), SP2/0 (B), PC12 (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, IHC, WB 100 μL Disponible
$363.46
Détails
Humain Lapin Inconjugué IHC, ELISA, WB   100 μg 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of extracts from 293 cells, using Cytochrome P450 8B1 antibody.The lane on the left is treated with the antigen-specific peptide. ABIN6275826 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué EIA, WB   0.4 mL 4 to 8 Days
$522.50
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of CYP8B1 Antibody in K562 cell line lysates (35ug/lane) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CYP8B1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué IHC, ELISA, WB   100 μg 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB   100 μL 11 to 14 Days
$757.17
Détails

Plus d’anticorps contre CYP8B1 partenaires d’interaction

Human Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1) interaction partners

  1. RORalpha is a key regulator of diurnal rhythm and fasting induction of CYP8B1, which regulates bile acid composition and serum and liver cholesterol levels.

  2. The single nucleotide polymorphism rs3732860 in the 3'-untranslated region of the CYP8B1 gene is associated with risk of Gallstone Disease in Chinese Han.

  3. SNP rs3732860 of CYP8B1 gene is associated with gallstone disease in this Chinese population.

  4. Cholesterol loading reduces SREBP-1 mRNA expression in addition to reducing functional SREBP-1 protein, and results in decreasing CYP8B1 gene transcription.

  5. Studies indicate a homogenous pattern for CYP8B1 expression in human liver, which was even rather than zonal.

  6. T(3) dose-dependently decreased total bile acid formation in parallel with decreased expression of CYP7A1 and CYP8B1

  7. Isoflavone-related induction of 12-alpha-hydroxylase (CYP8B1) was studied in vitro and murine in vivo models.

Mouse (Murine) Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1) interaction partners

  1. The altered bile acid composition of Cyp8b1(-/-) mice preserves metabolic and respiratory function by repressing hepatic De Novo lipogenesis and driving favorable changes in gut antimicrobial responses.

  2. Cyp8b1(-/-) mice were resistant to Western diet-induced body weight gain, hepatic steatosis, and insulin resistance.

  3. Absence of Cyp8b1 results in improved glucose tolerance, insulin sensitivity, and beta-cell function, mediated by absence of cholic acid in Cyp8b1(-/-) mice.

  4. Cholesterol lowering properties of oats involve increased production of bile acids via the classic pathway with up-regulation of CYP7A1 and CYP8B1.

  5. RORalpha is a key regulator of diurnal rhythm and fasting induction of CYP8B1, which regulates bile acid composition and serum and liver cholesterol levels.

  6. Feedback regulation of the rate-limiting biosynthetic enzyme CYP7A1 is lost in Cyp8b1(-/-) mice, causing expansion of the bile acid pool and alterations in cholesterol metabolism.

  7. In the intercross between C57BL/6J and CASA/Rk mice, Cyp8b1 is not responsible for biliary bile acid composition.

  8. The expression pattern of Cyp8b1 was studied in hepatocytes.

  9. Isoflavone-related induction of 12-alpha-hydroxylase (CYP8B1) was studied in vitro and murine in vivo models.

CYP8B1 profil antigène

Profil protéine

Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha- hydroxylated C27 steroids.

Gene names and symbols associated with CYP8B1

  • cytochrome P450 family 8 subfamily B member 1 (Cyp8b1) anticorps
  • cytochrome P450 family 8 subfamily B member 1 S homeolog (cyp8b1.S) anticorps
  • cytochrome P450 family 8 subfamily B member 1 (CYP8B1) anticorps
  • cytochrome P450, family 8, subfamily B, polypeptide 1 (CYP8B1) anticorps
  • cytochrome P450, family 8, subfamily b, polypeptide 1 (Cyp8b1) anticorps
  • CP8B anticorps
  • CYP8B anticorps
  • CYP12 anticorps
  • MGC64456 anticorps

Protein level used designations for CYP8B1

7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase , cytochrome P450 8b1 sterol 12 alpha-hydrolase , cytochrome P450, 8b1, sterol 12 alpha-hydrolase , cytochrome P450, family 8, subfamily B, polypeptide 1 , cytochrome P450, family 8, subfamily B , 7 alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase , 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase , CYPVIIIB1 , cytochrome P450 8B1 , cytochrome P450, subfamily VIIIB (sterol 12-alpha-hydroxylase), polypeptide 1 , sterol 12-alpha-hydroxylase , sterol 12-alpha-hydrolase , sterol 12-alpha hydroxylase

GENE ID SPECIES
81924 Rattus norvegicus
379482 Xenopus laevis
425055 Gallus gallus
538964 Bos taurus
1582 Homo sapiens
13124 Mus musculus
100009301 Oryctolagus cuniculus
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