anti-DDB1 and CUL4 Associated Factor 11 (DCAF11) Anticorps

DCAF11 encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. De plus, nous expédions DCAF11 Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DCAF11 80344 Q8TEB1
DCAF11 28199 Q91VU6
DCAF11 305895 Q5M9G8
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Top anti-DCAF11 Anticorps sur anticorps-enligne.fr

Showing 10 out of 25 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-WDR23 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Placenta Rabbit Anti-DCAF11 Antibody      Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver   Observed Staining: Cytoplasm in hepatocytes, strong signal, moderate tissue distribution  Primary Antibody Concentration: 1:100  Secondary Antibody: Donkey anti-Rabbit-Cy3  Secondary Antibody Concentration: 1:200  Magnification: 20X  Exposure Time: 0.5 – 2.0 sec  Protocol located in Reviews and Data. 100 μL 2 to 3 Days
$319.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-Dcaf11 Antibody   Titration: 1.0 ug/ml   Positive Control: Mouse pancreas 100 μL 2 to 3 Days
$319.00
Détails
Cobaye Lapin Inconjugué WB 100 μL 11 to 14 Days
$581.17
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μL 11 to 14 Days
$581.17
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué WB 50 μg 9 to 11 Days
$449.29
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using DCAF11 antibody. 200 μL 12 to 14 Days
$438.90
Détails
Humain Lapin Inconjugué IHC (p), WB Immunohistochemical staining of human kidney with WDR23 polyclonal antibody  shows moderate to strong positivity in tubular cells at 1:20-1:50 dilution. Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with WDR23 polyclonal antibody  at 1:250-1:500 dilution. 100 μL 11 to 12 Days
$577.33
Détails
Humain Lapin HRP IHC (p), WB   100 μL 14 to 21 Days
$416.90
Détails
Humain Lapin Cy5 IF (p)   100 μL 14 to 21 Days
$416.90
Détails

Plus d’anticorps contre DCAF11 partenaires d’interaction

Human DDB1 and CUL4 Associated Factor 11 (DCAF11) interaction partners

  1. results support a model in which the activation of the TNF-alpha/NF-kappaB axis contributes to an increase in CRL4B(DCAF)(11) activity and a decrease in p21(Cip1) protein levels, thereby controlling cell cycle progression in human osteosarcoma cells.

  2. Here, the authors demonstrated that CUL4B forms an E3 ligase with RBX1 (RING-box 1), DDB1 (DNA damage binding protein 1), and DCAF11 (DDB1 and CUL4 associated factor 11) that promotes the ubiquitination of p21(Cip1) and regulates cell cycle progression in human osteosarcoma cells.

  3. CRL4(WDR23) is required for efficient histone mRNA 3' end processing to produce mature histone mRNAs for translation. CRL4(WDR23) binds and ubiquitylates SLBP in vitro and in vivo, and this modification activates SLBP function in histone mRNA 3' end processing without affecting its protein levels.

  4. CRL4-DCAF11 mediates the degradation of SLBP at the end of S phase and this degradation is essential for the viability of cells.

  5. ur results identify WDR23 as an alternative regulator of NRF2 proteostasis and uncover a cellular pathway that regulates NRF2 activity and capacity for cytoprotection independently of KEAP1.

  6. Includes the functional characterization of a similar protein in C. elegans and comparison to the human protein.

DCAF11 profil antigène

Profil protéine

This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with DCAF11

  • DDB1 and CUL4 associated factor 11 L homeolog (dcaf11.L) anticorps
  • DDB1 and CUL4 associated factor 11 (dcaf11) anticorps
  • DDB1 and CUL4 associated factor 11 (DCAF11) anticorps
  • ddb1 and cul4 associated factor 11 (dcaf11) anticorps
  • DDB1 and CUL4 associated factor 11 (Dcaf11) anticorps
  • 0710008A13Rik anticorps
  • C76035 anticorps
  • D14Ucla1 anticorps
  • Dacf11 anticorps
  • DKFZP459A2062 anticorps
  • GLO14 anticorps
  • MGC53214 anticorps
  • MGC88880 anticorps
  • PRO2389 anticorps
  • Wdr23 anticorps
  • zgc:110066 anticorps

Protein level used designations for DCAF11

DDB1 and CUL4 associated factor 11 , WD repeat domain 23 , DDB1- and CUL4-associated factor 11 , WD repeat-containing protein 23

GENE ID SPECIES
380436 Xenopus laevis
448206 Xenopus (Silurana) tropicalis
452808 Pan troglodytes
567578 Danio rerio
714867 Macaca mulatta
100173316 Pongo abelii
100189652 Pongo abelii
100606408 Nomascus leucogenys
80344 Homo sapiens
490621 Canis lupus familiaris
539433 Bos taurus
28199 Mus musculus
305895 Rattus norvegicus
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