DDB1 and CUL4 Associated Factor 7 Protéines (DCAF7)

DCAF7 encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. De plus, nous expédions DCAF7 Anticorps (60) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
DCAF7 10238 P61962
DCAF7 71833 P61963
Rat DCAF7 DCAF7 303602  
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Showing 4 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Escherichia coli (E. coli) Humain His-SUMO Tag 100 μg Connectez-vous pour afficher 11 Days
$411.40
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails

DCAF7 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Plus protéines pour DDB1 and CUL4 Associated Factor 7 (DCAF7) partenaires d'interaction

Zebrafish DDB1 and CUL4 Associated Factor 7 (DCAF7) interaction partners

  1. these findings reveal an indirect role for Wdr68 in the BMP-Edn1-Jag1b signaling hierarchy and dorso-anterior expression of dlx1a/2a.

  2. we show that while a GFP-Wdr68 fusion functionally substituted for craniofacial development in the zebrafish, that a Nuclear Export Signal (NES (Montrer NES Protéines)) fusion protein (GFPNESWdr68) failed to support craniofacial development

  3. The initial characterization of wdr68 suggests an important role in craniofacial development for the highly conserved Wdr68-Dyrk1 (Montrer DYRK1A Protéines) protein complexes.

Human DDB1 and CUL4 Associated Factor 7 (DCAF7) interaction partners

  1. Immunoprecipitation and pulldown experiments identified DCAF7 as an adaptor for the association of the adenovirus E1A (Montrer BCKDHA Protéines) protein with DYRK1A (Montrer DYRK1A Protéines) and HIPK2 (Montrer HIPK2 Protéines)

  2. knockdown of DCAF7 reduced the degradation of DNA ligase I (Montrer LIG1 Protéines) in response to inhibition of proliferation and replacement of ubiquitylated lysine residues reduced the in vitro ubiquitylation of DNA ligase I (Montrer LIG1 Protéines) by Cul4-DDB1 and DCAF7. In contrast, a different E3 ubiquitin ligase (Montrer MUL1 Protéines) regulates FEN-1 (Montrer FEN1 Protéines) turnover.

  3. results demonstrate that the molecular chaperone (Montrer HSP90AA1 Protéines) TRiC/CCT (Montrer TCP1 Protéines) is essential for correct protein folding, DYRK1A (Montrer DYRK1A Protéines) binding, and nuclear accumulation of WDR68.

  4. DYRK1A (Montrer DYRK1A Protéines) binds specifically to WDR68 in cells; the binding, but not the phosphorylation event, induces the nuclear translocation of WDR68.

  5. Han11 was required to allow coupling of MEKK1 (Montrer MAP3K1 Protéines) to DYRK1 (Montrer DYRK1A Protéines) and HIPK2 (Montrer HIPK2 Protéines).

  6. that AN11 may be a physiological regulator of GLI1 (Montrer GLI1 Protéines) transcriptional activity

Mouse (Murine) DDB1 and CUL4 Associated Factor 7 (DCAF7) interaction partners

  1. Depleting Huntingtin-associated protein 1 (Hap1 (Montrer HAP1 Protéines)) promoted the dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A (Montrer DYRK1A Protéines))-DDB1 and CUL4 associated factor 7 (Dcaf7) interaction and increased the DYRK1A (Montrer DYRK1A Protéines) protein level.

Profil protéine DCAF7

Profil protéine

This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signalling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with DCAF7

  • ddb1 and cul4 associated factor 7 (dcaf7)
  • DDB1 and CUL4 associated factor 7 S homeolog (dcaf7.S)
  • DDB1 and CUL4 associated factor 7 (dcaf7)
  • DDB1 and CUL4 associated factor 7 (DCAF7)
  • DDB1 and CUL4 associated factor 7 (Dcaf7)
  • 1700012F10Rik Protéine
  • 2610037L01Rik Protéine
  • AN11 Protéine
  • C86529 Protéine
  • cg14614 Protéine
  • fj83g06 Protéine
  • HAN11 Protéine
  • han11l Protéine
  • MGC53476 Protéine
  • MGC75622 Protéine
  • MGC80168 Protéine
  • RGD1305140 Protéine
  • SWAN-1 Protéine
  • Wdr68 Protéine
  • wu:fj83g06 Protéine
  • zgc:63940 Protéine

Protein level used designations for DCAF7

DDB1- and CUL4-associated factor 7 , dys , dirty south , AN11 homolog , WD repeat domain 68 , DDB1 and CUL4 associated factor 7 , WD-repeat protein , WD repeat-containing protein 68 , WD repeat-containing protein An11 homolog , human anthocyanin , seven-WD-repeat protein of the AN11 family-1

GENE ID SPECIES
337565 Danio rerio
380552 Xenopus laevis
394701 Xenopus (Silurana) tropicalis
454780 Pan troglodytes
516678 Bos taurus
612958 Canis lupus familiaris
100021497 Monodelphis domestica
100390366 Callithrix jacchus
100443948 Pongo abelii
100514182 Sus scrofa
10238 Homo sapiens
71833 Mus musculus
303602 Rattus norvegicus
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