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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. De plus, nous expédions DDX24 Protéines (4) et et beaucoup plus de produits pour cette protéine.
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Human Polyclonal DDX24 Primary Antibody pour IP, WB - ABIN151645
Yamauchi, Nishiyama, Moroishi, Yumimoto, Nakayama: MDM2 mediates nonproteolytic polyubiquitylation of the DEAD-Box RNA helicase DDX24. dans Molecular and cellular biology 2014
Human Polyclonal DDX24 Primary Antibody pour ICC, IF - ABIN4304620
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. dans Nature methods 2013
DDX24 is a negative regulator of p53 (Montrer TP53 Anticorps) transcriptional activity.DDX24 inhibits p300 (Montrer EP300 Anticorps) mediated acetylation of p53 (Montrer TP53 Anticorps).
depletion of DDX24 in cells impaired pre-rRNA processing and resulted both in abrogation of MDM2 (Montrer MDM2 Anticorps) function and in consequent p53 (Montrer TP53 Anticorps) stabilization
knockdown of a DEAD-box protein (Montrer INTS6 Anticorps) named DDX24 inhibits the packaging of HIV-1 RNA and thus diminishes viral infectivity.
data provide a new function for DDX24 and help explain innate immune gene regulation, mechanisms that may additionally provide insight into the causes of inflammatory disease.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level.
ATP-dependent RNA helicase DDX24
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
, hypothetical protein LOC553462
, ATP-dependent RNA helicase DDX24-like
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 24
, DEAD box protein 24
, S. cerevisiae CHL1-like helicase
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 13 (RNA helicase A)