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DHX33 encodes a member of the DEAD box protein family. De plus, nous expédions DEAH (Asp-Glu-Ala-His) Box Polypeptide 33 Protéines (2) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal DHX33 Primary Antibody pour ICC, IF - ABIN251021
Zhang, Forys, Miceli, Gwinn, Weber: Identification of DHX33 as a mediator of rRNA synthesis and cell growth. dans Molecular and cellular biology 2011
Show all 5 Pubmed References
In clinical samples, the expression of Rab1A (Montrer RAB1A Anticorps) or DHX33 was reversely correlated with miR (Montrer MLXIP Anticorps)-634. Re-expression of Rab1A (Montrer RAB1A Anticorps) or DHX33 abrogated the miR (Montrer MLXIP Anticorps)-634-mediated inhibition of cell proliferation and migration. Collectively, our data suggest a tumor suppressor role of miR (Montrer MLXIP Anticorps)-634 in hepatocellular carcinoma.
High expression of DHX33 is associated with non-Hodgkin's lymphoma and acute myeloid leukemia (Montrer BCL11A Anticorps).
Study demonstrates that DHX33 acts as a direct transcriptional regulator to promote cell cycle progression and plays an important role in driving cell proliferation during both embryo development and tumorigenesis.
Our data therefore suggest DHX33 is overexpressed in HCC (Montrer FAM126A Anticorps) and serves as a promising prognostic biomarker for this deadly disease.
The results reveal a newly recognized function of DHX33 in mRNA translation initiation, further solidifying its central role in promoting cell growth and proliferation.
Data indicate that DHX33 forms the inflammasome complex with NLRP3 (Montrer NLRP3 Anticorps) following stimulation with cytosolic RNA.
results directly implicate DHX33 as a crucial player in establishing rRNA synthesis rates in the face of Ras(V12) or ARF signals, adjusting ribosome biogenesis to match the appropriate growth or antigrowth signals.
we show the mechanistic importance of DHX33 in rRNA transcription and proliferation
results directly implicate DHX33 as a crucial player in establishing rRNA synthesis rates in the face of Ras(V12) or ARF signals, adjusting ribosome biogenesis to match the appropriate growth or antigrowth signals
This gene encodes a member of the DEAD box protein family. The DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Alternative splicing results in multiple transcript variants.
DEAH (Asp-Glu-Ala-His) box polypeptide 33
, putative ATP-dependent RNA helicase DHX33
, putative ATP-dependent RNA helicase DHX33-like
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 33
, DEAH box protein 33