anti-DEK Oncogene (DEK) Anticorps

DEK encodes a protein with one SAP domain. De plus, nous expédions DEK Kits (7) et DEK Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DEK 7913 P35659
DEK 306817 Q6AXS3
DEK 110052 Q7TNV0
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Top anti-DEK Anticorps sur

Showing 10 out of 73 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-DEK Antibody Titration:  1.25ug/ml  ELISA Titer:  1:62500  Positive Control:  Jurkat cell lysate 100 μL 2 to 3 Days
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-DEK Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  MCF7 cell lysate 100 μL 2 to 3 Days
Humain Lapin Inconjugué EIA, FACS, IF, IHC (p), WB DEK Antibody (C-term) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of DEK Antibody (C-term) (Cat#AP51234PU-N) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL 6 to 8 Days
Boeuf (Vache) Lapin Inconjugué WB 100 μL 11 to 14 Days
Boeuf (Vache) Lapin Inconjugué WB 100 μL 11 to 14 Days
Humain Lapin Inconjugué IHC, WB ABIN6272941 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of HeLa cells, using DEK antibody. 100 μL 11 to 12 Days
Humain Lapin Inconjugué WB Western blot analysis of extracts of PC3 cell lines, using DEK antibody. Western blot analysis of extracts of various cell lines, using DEK antibody (ABIN4903467) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s. 100 μL 11 to 13 Days
Humain Lapin Inconjugué FACS, IF, IHC (p), WB Western blot analysis of lysates from U-251 MG, PC-3 cell line (from left to right), using DEK Antibody at 1:1000 at each lane. DEK Antibody IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
Humain Lapin Inconjugué ELISA, WB 100 μL 2 to 3 Days
Humain Lapin Alexa Fluor 647 IF (p)   100 μL 14 to 21 Days

anti-DEK Anticorps mieux référencés

  1. Human Polyclonal DEK Primary Antibody pour IHC (p), IP - ABIN253197 : Datta, Adelson, Mogilevkin, Mordechai, Sidi, Trama: Oncoprotein DEK as a tissue and urinary biomarker for bladder cancer. dans BMC cancer 2011 (PubMed)

  2. Cow (Bovine) Polyclonal DEK Primary Antibody pour WB - ABIN2792529 : Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer. dans Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal DEK Primary Antibody pour IF, IHC - ABIN1085125 : Matrka, Cimperman, Haas, Guasch, Ehrman, Waclaw, Komurov, Lane, Wikenheiser-Brokamp, Wells: Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence. dans PLoS genetics 2018 (PubMed)

  4. Human Polyclonal DEK Primary Antibody pour IF (p), IHC (p) - ABIN729268 : Yang, Wu, Geng, Liu, Yang, Chen, Ding, He, Wang, Xie: Roles of DEK in the endometrium of mice in early pregnancy. dans Gene 2017 (PubMed)

  5. Cow (Bovine) Polyclonal DEK Primary Antibody pour WB - ABIN2792543 : Orlic, Spencer, Wang, Gallie: Expression analysis of 6p22 genomic gain in retinoblastoma. dans Genes, chromosomes & cancer 2005 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre DEK partenaires d’interaction

Human DEK Oncogene (DEK) interaction partners

  1. DEK is overexpressed in HGSOCs, and decreasing DEK levels significantly reduces cell viability and tumor growth, resulting in apoptotic cell death.

  2. These findings define DEK as an important and multifunctional mediator of homologous recombination.

  3. DEK is detected in spontaneously forming neutrophil extracellular traps (NETs) from juvenile idiopathic arthritis patient synovial neutrophils, and DEK-targeted aptamers reduce NETs formation.

  4. High DEK proto-oncogene protein (DEK) expression associated with complete response to neoadjuvant chemoradiotherapy.

  5. High DEK expression is associated with cervical cancer tumorigenesis and metastasis.

  6. The results of the present study demonstrated that EMT of colorectal carcinoma cells was partially mediated by DEK, which likely affected the invasive ability of colorectal carcinoma cells. In addition, cell proliferation and apoptosis were susceptible to DEK silencing.

  7. RNA-sequencing proved to be a valuable tool for the detection of a fusion of genes DEK and NUP214 in a leukemia that showed cryptic cytogenetic rearrangement of chromosome band 9q34.

  8. DEK overexpression enhanced carcinogenesis, including field cancerization, in OSCC by stimulating the G1 /S phase transition and promoting DNA replication.

  9. DEK and LCMR1 were demonstrated to cooperate in the inhibition of apoptosis in lung cancer cells.

  10. High DEK expression is associated with breast cancer angiogenesis .

  11. our study indicates that DEK expression is required for tumorigenesis and metastasis of hepatocellular carcinoma

  12. High DEK expression is associated with melanoma progression.

  13. DEK correlates with IL6 expression in HPV16+/p16+ oropharyngeal squamous cell carcinomas (OPSCC).

  14. data support a scenario whereby overexpression of the human DEK oncogene reprograms keratinocyte metabolism to fulfill energy and macromolecule demands required to enable and sustain cancer cell growth

  15. Decreased DEK expression in plasma cells suggests a potential role of this gene in plasma cell development and lack of detectable DEK protein by IHC could be used as a biomarker for normal and malignant plasma cells

  16. Our data indicated DEK plays multiple roles to facilitate tumor growth and maintenance. It can be used as a potential target for astrocytic tumor diagnosis and gene therapy.

  17. High DEK expression is associated with pancreatic ductal adenocarcinoma.

  18. AP-2a is an important transcription factor of DEK expression, which is correlated with the methylation level of the DEK core promoter in hepatocellular carcinoma .

  19. miR-592 targets DEK transcript and suppresses hepatocellular carcinoma cell growth

  20. Results find that DEK binds to transcription start sites with a dual role in activation and repression of highly and ubiquitously expressed genes.

Mouse (Murine) DEK Oncogene (DEK) interaction partners

  1. These findings define DEK as an important and multifunctional mediator of homologous recombination.

  2. DEK is crucial to the development of arthritis in mouse models, thus making it an appropriate target for aptamer-based therapy.

  3. DEK was expressed throughout the brain in both sexes, including the medial prefrontal cortex (prelimbic, infralimbic and dorsal peduncular). DEK was also abundant in all amygdalar subdivisions (basolateral, central and medial) and in the hippocampus including the CA1, CA2, CA3, dentate gyrus (DG), ventral subiculum and entorhinal cortex.

  4. Dek contributes to esophageal squamous cell carcinoma tumorigenesis at least partially through keratinocyte intrinsic pathways which promote cellular and tumor growth.

  5. Data suggests that DEK participates in the process of embryo implantation and might play a role in influencing stromal cell decidualization through mediating cell proliferation, apoptosis and DNA damage.

  6. DEK expression during normal hematopoiesis did reveal a relationship with specific cell types implicating a distinct function during myeloid differentiation

  7. Studies demonstrate that DEK overexpression, due in part to Ron receptor activation, drives breast cancer progression through the induction of Wnt/beta-catenin signaling.

  8. Results highlight a novel function of DEK as a guardian of chromatin by restricting widespread histone access, and in particular by modulating differential H3.3 loading in specific chromatin areas.

  9. data demonstrate that DEK stimulates HNSCC cellular growth and identify DeltaNp63 as a novel DEK effector

  10. DEK has potent effects on HSCs, HPCs, and hematopoiesis, information of biological and potential clinical interest.

  11. The hallmark of translocation in acutte myeloid leukemiaa is the expression of the DEK/CAN fusion protein.

  12. DEK is a neuroblastoma tumor antigen.

  13. Our conclusion is that DEK could serve as an architectural protein at the promoter or enhancer sites of a subfraction of human genes.

  14. Overexpression of the cellular DEK protein promotes epithelial transformation in vitro and in vivo.

DEK profil antigène

Profil protéine

This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-DEK Oncogene (DEK) Anticorps

  • DEK proto-oncogene (DEK) anticorps
  • DEK proto-oncogene (Dek) anticorps
  • DEK proto-oncogene L homeolog (dek.L) anticorps
  • DEK oncogene (DNA binding) (Dek) anticorps
  • DEK oncogene (LOC398543) anticorps
  • 1810019E15Rik anticorps
  • D6S231E anticorps
  • D13H6S231E anticorps
  • DEK anticorps

Protein level used designations for anti-DEK Oncogene (DEK) Anticorps

DEK oncogene (DNA binding) , protein DEK , DEK oncogene

7913 Homo sapiens
306817 Rattus norvegicus
462460 Pan troglodytes
540945 Bos taurus
610538 Canis lupus familiaris
100340537 Oryctolagus cuniculus
100380963 Xenopus laevis
110052 Mus musculus
420828 Gallus gallus
101090769 Felis catus
100731281 Cavia porcellus
100156871 Sus scrofa
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