anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Anticorps

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. De plus, nous expédions DNA (Cytosine-5)-Methyltransferase 1 Kits (31) et DNA (Cytosine-5)-Methyltransferase 1 Protéines (10) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DNMT1 1786 P26358
DNMT1 84350  
DNMT1 13433 P13864
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Top anti-DNA (Cytosine-5)-Methyltransferase 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 537 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué ChIP, CyTOF, FACS, ICC, IF, IHC, IHC (ff), IHC (fro), IHC (p), IP, SimWes, WB Western Blot: Dnmt1 Antibody (60B1220.1) [ABIN252481] - Western blot analysis for Dnmt1 using ABIN252481 at 2 ug/ml against 10 µg of cell lysates of mouse ES cell. Immunohistochemistry: Dnmt1 Antibody (60B1220.1) [ABIN252481] - IHC analysis of Dnmt1 using ABIN252481 at 2 ug/ml on formalin-fixed, paraffin-embedded medullar kidney tissue sections 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails
Humain Souris Inconjugué ChIP, IP, IHC, WB DNMT1 antibody (mAb) tested by Western blot. Detection of DNMT1 by Western blot. The analysis was performed using mouse ES whole-cell extract and DNMT1 antibody (mAb) at a 2 µg/ml dilution. 100 μg Connectez-vous pour afficher 1 to 2 Days
$495.83
Détails
Souris Lapin Inconjugué WB Researcher: AnonymousApplication: Western BlottingSpecies+tissue/cell type: Lane 1:241 µg mouse mesenchymal stem cell lysate Primary Antibody dilution: 1:0000<br />Secondary Antibody: Anti-rabbit-HRP <br />Secondary Antibody Dilution: 1:00,000 WB Suggested Anti-Dnmt1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Mouse Lung 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of DNMT1 Antibody (S1105) (ABIN387879) in MDA-MB435 cell line lysates (35 µg/lane). DNMT1 (arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué FACS, WB The anti-Dnmt1 C-term Pab (ABIN387878) is used in Western blot to detect Dnmt1 in Jurkat cell lysate. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué DB Dot blot analysis of anti-Dnmt1 Phospho-specific Pab (ABIN389901) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Poisson Souris Inconjugué ChIP, IP, IHC, WB Dnmt1, 18ug H1299 lysate 1 in1000 Western Blotting. 100 μg Connectez-vous pour afficher 2 to 3 Days
$383.90
Détails
Poisson Souris Inconjugué ChIP, IP, IHC, WB Dnmt1, 18ug H1299 lysate 1 in1000 Western Blotting. 100 μg Connectez-vous pour afficher 2 to 3 Days
$383.90
Détails
Humain Souris Inconjugué ELISA, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using DNMT1 mAb against human DNMT1 recombinant protein. (Expected MW is 42.6 kDa) Dilution: 1/500 - 1/2000 100 μL Connectez-vous pour afficher 8 to 11 Days
$561.00
Détails
Humain Souris Inconjugué ELISA, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using DNMT1 mAb against human DNMT1 (AA: 1317-1616) recombinant protein. (Expected MW is 59.3 kDa) 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$561.00
Détails

anti-DNA (Cytosine-5)-Methyltransferase 1 Anticorps mieux référencés

  1. Human Monoclonal DNMT1 Primary Antibody pour ChIP, CyTOF - ABIN252481 : Dennis, Fan, Geiman, Yan, Muegge: Lsh, a member of the SNF2 family, is required for genome-wide methylation. dans Genes & development 2001 (PubMed)
    Show all 106 Pubmed References

  2. Human Monoclonal DNMT1 Primary Antibody pour ChIP, IP - ABIN2668504 : Schnekenburger, Talaska, Puga: Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. dans Molecular and cellular biology 2007 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal DNMT1 Primary Antibody pour DB, ELISA - ABIN4369817 : Saito, Kanai, Nakagawa, Sakamoto, Saito, Ishii, Hirohashi: Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas. dans International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal DNMT1 Primary Antibody pour WB - ABIN387879 : Peterson, Bögler, Taylor: p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding. dans Cancer research 2003 (PubMed)
    Show all 7 Pubmed References

  5. Human Polyclonal DNMT1 Primary Antibody pour FACS, WB - ABIN387878 : Leu, Rahmatpanah, Shi, Wei, Liu, Yan, Huang: Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation. dans Cancer research 2003 (PubMed)
    Show all 7 Pubmed References

  6. Human Polyclonal DNMT1 Primary Antibody pour IHC (p), IHC - ABIN314281 : Nanduri, Makarenko, Reddy, Yuan, Pawar, Wang, Khan, Zhang, Kinsman, Peng, Kumar, Fox, Godley, Semenza, Prabhakar: Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis. dans Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal DNMT1 Primary Antibody pour EIA - ABIN358462 : Liao, Siu, Chan, Wong, Ngan, Chan, Li, Khoo, Cheung: Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis. dans International journal of cancer. Journal international du cancer 2008 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal DNMT1 Primary Antibody pour EIA - ABIN358447 : Yang, Andrade, Labialle, Moussette, Geneau, Sinnett, Belisle, Greenwood, Naumova: Parental effect of DNA (Cytosine-5) methyltransferase 1 on grandparental-origin-dependent transmission ratio distortion in mouse crosses and human families. dans Genetics 2008 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal DNMT1 Primary Antibody pour IF (p), IHC (p) - ABIN671796 : Khan, Tania, Wei, Mei, Fu, Cheng, Xu, Fu: Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition. dans Oncotarget 2015 (PubMed)

  10. Human Polyclonal DNMT1 Primary Antibody pour IF (p), IHC (p) - ABIN757717 : Tan, Xu, Zeisberg, Zeisberg: High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation. dans Biochemical and biophysical research communications 2016 (PubMed)

Plus d’anticorps contre DNA (Cytosine-5)-Methyltransferase 1 partenaires d’interaction

Zebrafish DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Dnmt1 stability requires UHRF1 (Montrer UHRF1 Anticorps) phosphorylation and that crosstalk between the proteins is essential for the function of these two important epigenetic regulators during gastrulation

  2. Lsh (Montrer HELLS Anticorps) Is Essential for Maintaining Global DNA Methylation (Montrer HELLS Anticorps) Levels in Amphibia and Fish and Interacts Directly with Dnmt1.

  3. Dnmt1 is required for hematopoietic stem and progenitor cells maintenance via cebpa (Montrer CEBPA Anticorps) regulation during definitive hematopoiesis in zebrafish

  4. These data provide the first evidence that Uhrf1 (Montrer UHRF1 Anticorps) and Dnmt1 function is required for vertebrate lens development and maintenance.

  5. These results suggest that Dnmt1 activity helps direct histone methylation by Suv39h1 (Montrer SUV39H1 Anticorps) and that, together, Dnmt1 and Suv39h1 (Montrer SUV39H1 Anticorps) help guide the terminal differentiation of particular tissues.

  6. Data show that in dnmt1 homozygous mutants, reactivation of gfp expression occurs in a reproducible subset of cells, raising the possibility of different sensitivities or alternative silencing mechanisms in discrete cell populations.

  7. Thus, our data suggest that Dnmt1 is dispensable for pancreatic duct or endocrine cell formation, but not for acinar cell survival. In addition, Dnmt1 may influence the differentiation of pancreatic beta cell progenitors.

Human DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. the expression of WIF-1 (Montrer WIF1 Anticorps) was low in GBC cells due to aberrant hypermethylation of its promoter region. Additionally, an alternative pathogenesis of GBC was indicated in which c-Jun (Montrer JUN Anticorps) causes hypermethylation of the WIF-1 (Montrer WIF1 Anticorps) promoter region, and represses the expression of WIF-1 (Montrer WIF1 Anticorps) through transcriptional regulation and interaction with DNMT1 as an early event in the tumorigenesis of GBC.

  2. DNMT1 was downregulated in the Lung Cancer group and its expression was further reduced in the presence of increasing malignant burden as indicated by the endobronchial findings further suggesting an Lung Cancer-specific signature.

  3. SAC (Montrer ADCY10 Anticorps) decreased the levels of 5-methylcytosine, DNMT activity, messenger RNA (mRNA) and protein levels of DNMT1. Additionally, SAC (Montrer ADCY10 Anticorps) treatment resulted in re-expression of the mRNA and proteins of silenced tumor suppressor gene CDKN1A accompany with reduced cell division control 2 (Montrer CDK1 Anticorps) expression.

  4. This work revealed the critical function of GOLM1 (Montrer GOLM1 Anticorps)/miR (Montrer MLXIP Anticorps)-200a/DNMT1 signaling pathway on regulating lung adenocarcinoma cell proliferation

  5. DNMT1 is associated with cell cycle and DNA replication gene sets in diffuse large B-cell lymphoma

  6. both messenger RNA and protein levels of KLF2 (Montrer KLF2 Anticorps) in HUVEC co-treated with LPS (Montrer IRF6 Anticorps) and DNA methyltransferase (DNMT) 1 small interfering RNA were dramatically higher than that treated with LPS (Montrer IRF6 Anticorps) only.

  7. By perturbing BCL11A (Montrer BCL11A Anticorps)-DNMT1 interaction, miR (Montrer MLXIP Anticorps)-137 impairs cancer stemness and suppresses tumor development in Triple negative breast cancer.

  8. DNMT3B (Montrer DNMT3B Anticorps) rs1569686 gene polymorphism in women might be a genetic marker for the susceptibility to recurrent spontaneous abortion

  9. we demonstrated that the downregulation of CLDN6 (Montrer CLDN6 Anticorps) is regulated through promoter methylation by DNMT1, which depends on the SMAD2 (Montrer SMAD2 Anticorps) pathway, and that CLDN6 (Montrer CLDN6 Anticorps) is a key regulator in the SMAD2 (Montrer SMAD2 Anticorps)/DNMT1/CLDN6 (Montrer CLDN6 Anticorps) pathway to inhibit EMT (Montrer ITK Anticorps), migration and invasion of breast cancer cells

  10. GNAO1 (Montrer GNAO1 Anticorps) transcription was inhibited by promoter hypermethylation, contributing to its low expression. It was further revealed that the silencing effect was regulated by methyltransferase 1 (DNMT1), and was further enhanced by transforming growth factor beta (TGF-beta).

Pig (Porcine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Dnmt1 was indispensable for oocyte cytoplasmic maturation, providing a novel role for Dnmt1 in the regulation of oocyte maturation.

  2. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1, Dnmt3a (Montrer DNMT3A Anticorps), Hdac1 (Montrer HDAC1 Anticorps), Kdm3a (Montrer KDM3A Anticorps) and Uhrf1 (Montrer UHRF1 Anticorps) were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

  3. DNMT1o is localized mainly in the nuclei of oocytes and early embryos, whereas DNMT1s is expressed in the ooplasm (Montrer NLRP5 Anticorps) cortex of oocytes and cytoplasm of early embryos.

  4. results indicate that loss of Dnmt1 in the maternal nucleus during SCNT significantly contributes to the unfaithful maintenance of methylation imprints in cloned embryos

  5. Oocyte-specific Dnmt1 is cytoplasmic during early development.

  6. Dnmt1 mRNA abundance plays an important role during protein regulation, Dnmt1 enzyme is mainly posttranscriptionally regulated.

Cow (Bovine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. DNMT1 silencing significantly decreased the methylation levels of miR (Montrer MYLIP Anticorps)-29b promoter, up-regulated miR (Montrer MYLIP Anticorps)-29b expression and inhibited bovine viral diarrhea virus replication.

  2. Through down-regulating the expression of DNMT1, miR (Montrer MYLIP Anticorps)-152 reduced Global DNA methylation (Montrer HELLS Anticorps) and the activity of DNMT to reactivate the lactation signal transduction genes Akt (Montrer AKT1 Anticorps) and Ppar gamma (Montrer PPARG Anticorps).

  3. More DNMT1 mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (Montrer ASCL2 Anticorps) mRNA was present at highest levels in transgenic SCNT embryos.

  4. Our results indicate an essential role for Dnmt1 during bovine preimplantation development (Montrer MTA2 Anticorps), and suggest proper transcriptional reprogramming of this gene family in SCNT embryos.

  5. Abnormal gene expression of DNMT, INFT, and MHC1 was noted in the majority of cloned embryos, indicating inefficient nuclear reprogramming and retarded embryo development.

  6. Results describe the alternative splicing and expression analysis of bovine DNA methyltransferase 1.

  7. Report inhibition of DNA methyltransferase 1 expression in bovine fibroblast cells used for nuclear transfer.

Arabidopsis thaliana DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. The findings reveal that MET1-mediated shoot regeneration is regulated by the cytokinin-induced cell cycle, and provide new insights into the regulation of DNA methylation (Montrer HELLS Anticorps) in shoot regeneration.

  2. Long-term stability and epigenetic features differ for individual loci. Our data show that over-expression of MET1, and potentially of other genes encoding epigenetic factors, offers an alternative strategy to identify epigenetic target genes and to create novel epi (Montrer TFPI Anticorps)-alleles

  3. MET1 confines ARID1 to the vegetative cell of male gametes, but ARID1 conversely represses MET1 in the central cell of female gametes.

  4. MET1 is a thylakoid-associated TPR protein involved in photosystem II supercomplex formation and repair in Arabidopsis

  5. Met1 gene expression throughout normal development, particularly in the flower

  6. MET1 is a contributor to epigenetic diversity in Arabidopsis.

  7. VIM (Montrer VIM Anticorps) proteins regulate genome-wide epigenetic gene silencing through coordinated modulation of DNA methylation (Montrer HELLS Anticorps) and histone modification status in collaboration with MET1

  8. VIM (Montrer VIM Anticorps) proteins function in transcriptional regulation via their roles in the MET1 DNA methylation (Montrer HELLS Anticorps) pathway.

  9. Genetic studies indicate that the Polycomb (Montrer CBX2 Anticorps) Repressive Complex 2 (PRC2) but not the DNA METHYLTRANSFERASE1 (MET1) is involved in regulating imprinted expression in the embryo. [MET1]

  10. MET1 restores body methylation, which is region-specific but random with respect to the affected CG sites, and is moderately although not decisively influenced by transcription.

Mouse (Murine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Increased shear stress without a change in flow direction initiates arteriogenic growth; however, it also elicits DNMT1-dependent endothelial cells DNA hypermethylation. In turn, this diminishes mechanosensing, augments shear stress set point, and constrains the ultimate arteriogenic capacity of the vessel.

  2. Single-cell transcriptome analysis detected Dnmt1 expression in murine migratory GABAergic embryonic preoptic area (POA)-derived cells. Deletion of Dnmt1 in postmitotic immature cells of the POA caused defective migration and severely diminished adult cortical interneuron numbers. DNMT1 preserves the migratory shape in part through negative regulation of Pak6 (Montrer PAK6 Anticorps), which stimulates neuritogenesis postmigration.

  3. The aim of the present study is to investigate spatial and temporal expression levels and subcellular localizations of the DNMT1, DNMT3A (Montrer DNMT3A Anticorps), and DNMT3B (Montrer DNMT3B Anticorps) proteins in the mouse germinal vesicle (GV) and metaphase II (MII) oocytes, and early embryos from 1-cell to blastocyst stages.

  4. DNMT1 ablation from kidney proximal tubules enhanced cisplatin-induced acute kidney injury in mice, suggesting a renoprotective role of DNA methylation (Montrer HELLS Anticorps).

  5. Epigenetic enhancement of the post-replicative DNA mismatch repair of mammalian genomes by a Hemi-(m)CpG-Np95 (Montrer UHRF1 Anticorps)-Dnmt1 axis has been demonstrated for humans and mice.

  6. We show that expression of Id-1 (Montrer IDH1 Anticorps), a negative regulator of myogenesis, is enhanced in Dnmt1-deficient cultures, leading to enhanced transdifferentiation of myoblasts toward the osteogenic lineage. Thus, these studies demonstrate that Dnmt1 influences cellular identity and determines lineage fidelity.

  7. this study shows that DNMT1 might directly repress p53 (Montrer TP53 Anticorps), at least in part, by binding to the p53 (Montrer TP53 Anticorps) promoter locus

  8. Knockdown of DNMT3A (Montrer DNMT3A Anticorps) or DNMT1 protected neurons against mutant Htt (Montrer HTT Anticorps)-induced toxicity, together demonstrating a requirement for DNMTs in mutant Htt (Montrer HTT Anticorps)-triggered neuronal death and suggesting a neurodegenerative mechanism based on DNA methylation (Montrer HELLS Anticorps)-mediated transcriptional repression.

  9. Sp1 (Montrer SP1 Anticorps)/NFkappaB p65 (Montrer NFkBP65 Anticorps)-Dnmt1 pathway may be exploited as a therapeutic target for protecting against podocyte injury in diabetic nephropathy.

  10. 2-hydroxyglutarate bound to DNMT1 and stimulated its association with the RIP3 (Montrer MPRIP Anticorps) promoter, inducing hypermethylation that reduces RIP3 (Montrer MPRIP Anticorps) protein and consequently impaired RIP3 (Montrer MPRIP Anticorps)-dependent necroptosis.

DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) profil antigène

Profil protéine

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DNMT1

  • DNA methyltransferase 1 (DNMT1) anticorps
  • DNA (cytosine-5-)-methyltransferase 1 (dnmt1) anticorps
  • DNA methyltransferase 1 (Dnmt1) anticorps
  • methyltransferase 1 (MET1) anticorps
  • DNA methyltransferase (cytosine-5) 1 (Dnmt1) anticorps
  • ADCADN anticorps
  • AIM anticorps
  • cb983 anticorps
  • cb1075 anticorps
  • Cxxc9 anticorps
  • DDM2 anticorps
  • DECREASED DNA METHYLATION 2 anticorps
  • dmnt1 anticorps
  • DMT01 anticorps
  • DMT1 anticorps
  • DNA METHYLTRANSFERASE anticorps
  • DNA METHYLTRANSFERASE 01 anticorps
  • DNA METHYLTRANSFERASE 1 anticorps
  • Dnmt anticorps
  • Dnmt1o anticorps
  • fb05h01 anticorps
  • HSN1E anticorps
  • m.MmuI anticorps
  • MCMT anticorps
  • Met-1 anticorps
  • Met1 anticorps
  • MET2 anticorps
  • methyltransferase 1 anticorps
  • METHYLTRANSFERASE 2 anticorps
  • METHYLTRANSFERASE I anticorps
  • METI anticorps
  • MommeD2 anticorps
  • mta anticorps
  • MTase anticorps
  • wu:fb05h01 anticorps

Protein level used designations for DNMT1

DNA (cytosine-5)-methyltransferase 1 , ddn , CXXC-type zinc finger protein 9 , DNA MTase HsaI , DNA methyltransferase HsaI , m.HsaI , DNA methyltransferase 1 , DNA (cytosine 5 ) methyltransferase 1 , DNA methyltransferase (cytosine 5 ) methyltransferase , DNA methyltransferase b , DNA MTase RnoIP , DNA methyltransferase (cytosine-5) 1 , DNA methyltransferase I , MCMT , m.RnoIP , DNA MTase GgaI , DNA MeTase , DNA methyltransferase GgaI , m.GgaI , DNA MTase MmuI , DNA methyltransferase MmuI

GENE ID SPECIES
443549 Ovis aries
30430 Danio rerio
1786 Homo sapiens
476715 Canis lupus familiaris
606746 Sus scrofa
281119 Bos taurus
84350 Rattus norvegicus
396011 Gallus gallus
834975 Arabidopsis thaliana
13433 Mus musculus
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