anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) Anticorps

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. De plus, nous expédions DNA (Cytosine-5-)-Methyltransferase 3 Like Protéines (10) et DNA (Cytosine-5-)-Methyltransferase 3 Like Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TRDMT1 54427 Q9CWR8
TRDMT1 29947 Q9UJW3
TRDMT1 309680 Q1LZ50
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Top anti-DNA (Cytosine-5-)-Methyltransferase 3 Like Anticorps sur anticorps-enligne.fr

Showing 10 out of 189 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué AA, ICC, IF, IHC, IP, WB SMC 341DNMT3LRat Tissue Mix Western Blotting. 100 μg Connectez-vous pour afficher 2 to 3 Days
$383.90
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of Mouse Dnmt3L Antibody (ABIN387907) in Hela cell line lysates (35 µg/lane). Dnmt3l (arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué IHC (p), WB Dnmt3L-R322 (ABIN387892) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the DNMT3L antibody detected the DNMT3L protein (arrow). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Souris HRP AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Connectez-vous pour afficher 2 to 3 Days
$422.40
Détails
Humain Souris FITC AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Connectez-vous pour afficher 2 to 3 Days
$426.80
Détails
Humain Souris Alkaline Phosphatase (AP) AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Connectez-vous pour afficher 2 to 3 Days
$429.00
Détails
Humain Souris Biotin AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Connectez-vous pour afficher 2 to 3 Days
$431.20
Détails
Humain Souris PE AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Connectez-vous pour afficher 2 to 3 Days
$432.30
Détails

TRDMT1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-DNA (Cytosine-5-)-Methyltransferase 3 Like Anticorps mieux référencés

  1. Human Polyclonal TRDMT1 Primary Antibody pour IHC (p), WB - ABIN4305755 : Bonnin, Belville, Chiambaretta, Sapin, Blanchon: DNA methyl transferases are differentially expressed in the human anterior eye segment. dans Acta ophthalmologica 2014 (PubMed)

  2. Human Polyclonal TRDMT1 Primary Antibody pour IHC (p), WB - ABIN387892 : Chedin, Lieber, Hsieh: The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a. dans Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal TRDMT1 Primary Antibody pour WB - ABIN2668677 : Ajj, Chesnel, Pinel, Plenat, Flament, Dumond: An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism. dans PLoS ONE 2013 (PubMed)

  4. Mammalian Monoclonal TRDMT1 Primary Antibody pour ISt, IHC - ABIN1304620 : Satterlee, Beckel-Mitchener, McAllister, Procaccini, Rutter, Tyson, Chadwick: Community resources and technologies developed through the NIH Roadmap Epigenomics Program. dans Methods in molecular biology (Clifton, N.J.) 2014 (PubMed)

Plus d’anticorps contre DNA (Cytosine-5-)-Methyltransferase 3 Like partenaires d’interaction

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) interaction partners

  1. The Sirt1 (Montrer SIRT1 Anticorps) protein suppressed transcription of Dnmt3l.

  2. The Dnmt3l mutation greatly reduced DNA methylation (Montrer HELLS Anticorps) levels at most retrotransposons, but its impact on their RNA abundance was limited in prospermatogonia. In Pld6 (Montrer PLD6 Anticorps) mutant germ cells, although only a few retrotransposons exhibited reduced DNA methylation (Montrer HELLS Anticorps), many showed increased expression at the RNA level.

  3. Dnmt3l-KO donor cells may offer a more permissive epigenetic state that is beneficial for Nuclear transfer reprogramming

  4. By interacting with TRIM28 (Montrer TRIM28 Anticorps), DNMT3L can attract various enzymes to form a DNMT3L-induced repressive complex to remove active marks and add repressive marks to histone proteins.

  5. Hypomethylation of highly methylated CpG islands was caused by the downregulation of Dnmt3L and Dnmt3a (Montrer DNMT3A Anticorps) due to hepatitis B X-protein bound to their promoters.

  6. DNMT3L is required to delicately balance the cycling and quiescence of spermatogonial progenitor cells

  7. Study demonstrates that Dnmt3L interacts with the Polycomb (Montrer CBX2 Anticorps) PRC2 complex in competition with the DNA methyltransferases Dnmt3a (Montrer DNMT3A Anticorps) and Dnmt3b (Montrer DNMT3B Anticorps) to maintain low methylation levels at the Histone 3 H3K27me3 regions.

  8. Data indicate that expression of Dnmt3a (Montrer DNMT3A Anticorps), Dnmt3b (Montrer DNMT3B Anticorps), Dnmt3L as well as maintenance Dnmt1o (Montrer DNMT1 Anticorps) in oocytes and zygotes was not disrupted.

  9. Reduced expression of DNMT3L in male germ cells, associated with haploinsufficiency of the paternal-effect gene Dnmt3L, results in abnormal hypomethylation of prenatal germline progenitor cells.

  10. The maternal store of Dnmt3L is not involved in embryonic de novo methylation.

Human DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) interaction partners

  1. DNMT3L overexpression is associated with Down syndrome.

  2. the present study has demonstrated that variations in the DNMT3L gene do not contribute to stage I-II endometriosis-associated infertility.

  3. DNMT3L rs2070565 (genotype P = 0.007, allele P = 0.0026) confers an increased risk of developing schizophrenia at an early age in individuals with family history.

  4. crystal structures of DNMT3A (Montrer DNMT3A Anticorps)-DNMT3L (autoinhibitory form) and DNMT3A (Montrer DNMT3A Anticorps)-DNMT3L-H3 (active form) complexes at 3.82 and 2.90 A resolution, respectively

  5. DNMT3L can address DNMT3A (Montrer DNMT3A Anticorps)/B to specific sites by directly interacting with TFs that do not directly interact with DNMT3A (Montrer DNMT3A Anticorps)/B

  6. CpG island encompassing the promoter and first exon of human DNMT3L gene is a PcG/TrX (Montrer VAC14 Anticorps) response element

  7. DNMT3L is one of the key players in de novo DNA methylation (Montrer HELLS Anticorps) of imprinting control elements and retrotransposons, which occurs after genome-wide epigenetic erasure during germ cell development. (Review)

  8. SNP rs2070565, as well as haplotypes AAA (Montrer APP Anticorps) and GAA (Montrer GAA Anticorps), may be associated with male infertility; DNMT3L may contribute to azoospermia susceptibility in humans

  9. Genetic polymorphisms of DNMT3L involved in hypermethylation of chromosomal ends are associated with greater risk of developing ovarian endometriosis.

  10. mutation analysis of SYCP3 (Montrer SYCP3 Anticorps), DNMT3L and MSH4 (Montrer MSH4 Anticorps) in patients with maturation arrest of spermatogenesis and couples with recurrent miscarriages.

DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) profil antigène

Profil protéine

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TRDMT1

  • DNA methyltransferase 3 like (DNMT3L) anticorps
  • DNA (cytosine-5-)-methyltransferase 3-like (Dnmt3l) anticorps
  • DNA methyltransferase 3 like (Dnmt3l) anticorps
  • D6Ertd14e anticorps
  • DNMT3L anticorps
  • ecat7 anticorps

Protein level used designations for TRDMT1

DNA (cytosine-5-)-methyltransferase 3-like , cytosine-5-methyltransferase 3-like protein , DNA (cytosine-5)-methyltransferase 3-like , human cytosine-5-methyltransferase 3-like protein

GENE ID SPECIES
100050680 Equus caballus
470099 Pan troglodytes
613785 Bos taurus
608536 Canis lupus familiaris
54427 Mus musculus
29947 Homo sapiens
309680 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) Anticorps
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