anti-DNA Cross-Link Repair 1A (DCLRE1A) Anticorps

DCLRE1A encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. De plus, nous expédions et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DCLRE1A 9937 Q6PJP8
Anti-Rat DCLRE1A DCLRE1A 292127  
Anti-Souris DCLRE1A DCLRE1A 55947  
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Top anti-DNA Cross-Link Repair 1A Anticorps sur anticorps-enligne.fr

Showing 10 out of 40 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, IHC   100 μg 6 to 7 Days
$429.84
Détails
Humain Chèvre Inconjugué ELISA, IHC   100 μg 6 to 7 Days
$429.84
Détails
Humain Chèvre Inconjugué ELISA, IHC, IHC (p) Human Heart (formalin-fixed, paraffin-embedded) stained with DCLRE1A antibody ABIN291867 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-DCLRE1A / SNM1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Humain Chèvre Inconjugué ELISA, IHC, IHC (p) Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with DCLRE1A antibody ABIN298128 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-DCLRE1A / SNM1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué IF, IHC (p) Immunofluorescent staining of human cell line A-431 with DCLRE1A polyclonal antibody  at 1-4 ug/mL dilution shows positivity in nucleus and nucleoli. Immunohistochemical staining of human placenta with DCLRE1A polyclonal antibody  shows strong nuclear positivity in trophoblastic cells. 100 μL 11 to 12 Days
$577.33
Détails
Humain Chèvre APC ELISA   100 μL 16 Days
$653.71
Détails
Humain Chèvre APC ELISA   100 μL 16 Days
$653.71
Détails
Humain Chèvre Alkaline Phosphatase (AP) ELISA   100 μL 16 Days
$653.71
Détails
Humain Chèvre Biotin ELISA   100 μL 16 Days
$653.71
Détails
Humain Chèvre FITC ELISA   100 μL 16 Days
$653.71
Détails

anti-DNA Cross-Link Repair 1A Anticorps mieux référencés

  1. Human Polyclonal DCLRE1A Primary Antibody pour ELISA - ABIN547575 : Akhter, Richie, Deng, Brey, Zhang, Patrick, Behringer, Legerski: Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress. dans Molecular and cellular biology 2004 (PubMed)

  2. Human Polyclonal DCLRE1A Primary Antibody pour ELISA - ABIN547285 : Richie, Peterson, Lu, Hittelman, Carpenter, Legerski: hSnm1 colocalizes and physically associates with 53BP1 before and after DNA damage. dans Molecular and cellular biology 2002 (PubMed)

Plus d’anticorps contre DNA Cross-Link Repair 1A partenaires d’interaction

Human DNA Cross-Link Repair 1A (DCLRE1A) interaction partners

  1. Structure-specific endonuclease activity of SNM1A enables processing of a DNA interstrand crosslink.

  2. Strikingly, the addition of the single-stranded DNA (ssDNA)-binding replication protein A (RPA) selectively restores XPF-ERCC1 endonuclease activity on this structure. The 5'-3' exonuclease SNM1A can load from the XPF-ERCC1-RPA-induced incisions and digest past the crosslink to quantitatively complete the unhooking reaction.

  3. Different charge distributions along the DNA binding groove may account for the drastic difference in processivity and DNA digestion efficiency, including that of damaged substrates, between SNM1A and SNM1B.

  4. differences in the substrate selectivities of SNM1A and SNM1B are likely to be relevant to their in vivo roles

  5. collaboration between hSNM1A and XPF-ERCC1 is necessary to initiate interstrand cross-link repair in replicating human cells

  6. RAD18-dependent recruitment of SNM1A to DNA repair complexes by a ubiquitin-binding zinc finger

  7. Results suggest that 53BP1 and Snm1 may cooperate in the cellular response to genotoxic damage.

  8. Snm1 and 53BP1 are components of a mitotic stress checkpoint that negatively targets the APC prior to chromosome condensation

  9. The SNM1 enzyme utilizes either DNA or RNA substrates, requires a 5'-phosphate moiety, shows very little activity on double-strand substrates, and functions at a size consistent with a monomer.

  10. Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants.

  11. hSNM1 appears to represent a second pathway for genome stability

  12. These findings suggest that SNM1A acts with ATM to promote the G1 cell cycle checkpoint.

Mouse (Murine) DNA Cross-Link Repair 1A (DCLRE1A) interaction partners

  1. Snm1 and 53BP1 are components of a mitotic stress checkpoint that negatively targets the APC prior to chromosome condensation

  2. Snm1 is a tumor suppressor in mice that in addition has a role in immunity

DNA Cross-Link Repair 1A (DCLRE1A) profil antigène

Profil protéine

This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with DCLRE1A

  • DNA cross-link repair 1A (DCLRE1A) anticorps
  • DNA cross-link repair 1A (Dclre1a) anticorps
  • DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae) (dclre1a) anticorps
  • 2810043H12Rik anticorps
  • AU022226 anticorps
  • fc49f05 anticorps
  • im:7145629 anticorps
  • mKIAA0086 anticorps
  • Pso2 anticorps
  • Smn1a anticorps
  • Snm1 anticorps
  • Snm1-like anticorps
  • SNM1A anticorps
  • wu:fc49f05 anticorps
  • zgc:109999 anticorps

Protein level used designations for DCLRE1A

DNA cross-link repair 1A protein , DNA-crosslink repair gene SNM1 , SNM1 homolog A , DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae) , chSNM1A , DNA cross-link repair 1A , DNA cross-link repair 1A protein-like , LOW QUALITY PROTEIN: DNA cross-link repair 1A protein

GENE ID SPECIES
9937 Homo sapiens
292127 Rattus norvegicus
423902 Gallus gallus
477824 Canis lupus familiaris
504377 Bos taurus
100359072 Oryctolagus cuniculus
100467042 Ailuropoda melanoleuca
100593712 Nomascus leucogenys
55947 Mus musculus
100723290 Cavia porcellus
324964 Danio rerio
100156734 Sus scrofa
100068217 Equus caballus
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