DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Protéines (DCLRE1B)

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. De plus, nous expédions DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Anticorps (38) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
DCLRE1B 64858 Q9H816
DCLRE1B 310745 Q4KLY6
DCLRE1B 140917 Q8C7W7
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Protéines sur anticorps-enligne.fr

Showing 4 out of 4 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$9,797.11
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$9,797.11
Détails
Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$338.33
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,545.67
Détails

DCLRE1B Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Rat (Rattus)

Mouse (Murine)

Plus protéines pour DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) partenaires d'interaction

Human DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) interaction partners

  1. Different charge distributions along the DNA binding groove may account for the drastic difference in processivity and DNA digestion efficiency, including that of damaged substrates, between SNM1A and SNM1B.

  2. The SNM1B/APOLLO DNA nuclease (Montrer DCLRE1C Protéines) functions in resolution of replication stress and maintenance of common fragile site stability.

  3. the N-terminal region of Snm1B forms a complex containing PSF2 (Montrer TAP2 Protéines) and Mus81 (Montrer MUS81 Protéines), while the C-terminal region is important for PSF2 (Montrer TAP2 Protéines)-mediated chromatin association.

  4. The nuclease hSNM1B/Apollo is linked to the Fanconi anemia pathway via its interaction with FANCP/SLX4.

  5. differences in the substrate selectivities of SNM1A and SNM1B are likely to be relevant to their in vivo roles

  6. SNM1B functions epistatically to the central Fanconi anemia factor, FANCD2, in cellular survival after interstrand crosslinks damage and homology-directed repair of DNA double-strand breaks

  7. TRF2 (Montrer TERF2 Protéines), which binds preferentially to positively supercoiled DNA substrates, together with Apollo, negatively regulates the amount of TOP1 (Montrer TOP1 Protéines), TOP2alpha, and TOP2beta (Montrer TOP2B Protéines) at telomeres.

  8. siRNA knockdown of hSNM1B rendered cells sensitive to ionizing radiation, suggesting the possibility of hSNM1B involvement in homologous recombination repair of double-strand breaks arising as intermediates of ICL repair

  9. the C terminus of Snm1B was shown to interact with the TRF (Montrer IL5 Protéines) homology domain of TRF2 (Montrer TERF2 Protéines) indicating that Snm1B is likely recruited to the telomere via interaction with the double-stranded telomere-binding protein TRF2 (Montrer TERF2 Protéines)

  10. SNM1B (Apollo) protein exhibits a 5'-to-3' DNA exonuclease (Montrer EXO1 Protéines) activity and functions together with TRF2 (Montrer TERF2 Protéines) to protect telomeres from damage and fusion.

Mouse (Murine) DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) interaction partners

  1. Study documents the combinatorial action of Apollo, POT1b, CST (Montrer CORT Protéines), and the 5' exonuclease (Montrer EXO1 Protéines) Exo1 (Montrer EXO1 Protéines) in postreplicative telomere end processing in mouse cells, clarifying the mechanism by which the telomeric 3' overhang is generated and modulated.

  2. The telomeric protein (Montrer SYCE1 Protéines) SNM1B/Apollo is required for normal cell proliferation and embryonic development

  3. TRF2 (Montrer TERF2 Protéines)-bound Apollo functions at replicating telomeres, promoting the maintenance of the telomeric overhang, repressing S phase-specific ATM (Montrer ATM Protéines) signaling, and protecting leading-end telomeres from fusion.

  4. Apollo null mouse embryo fibroblasts exhibit an increased incidence of G2 chromatid-type fusions involving telomeres created by leading-strand DNA synthesis, reflective of a failure to protect these telomeres after DNA replication.

Profil protéine DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B)

Profil protéine

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000

Gene names and symbols associated with DCLRE1B

  • DNA cross-link repair 1B (DCLRE1B)
  • DNA cross-link repair 1B (Dclre1b)
  • DNA cross-link repair 1B (dclre1b)
  • AI452214 Protéine
  • Apollo Protéine
  • im:6894074 Protéine
  • mSNM1B Protéine
  • SNM1B Protéine
  • SNMIB Protéine
  • zgc:154089 Protéine

Protein level used designations for DCLRE1B

5' exonuclease Apollo , DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae) , PSO2 homolog , SNM1 homolog B , DNA cross-link repair 1B protein

GENE ID SPECIES
64858 Homo sapiens
428269 Gallus gallus
310745 Rattus norvegicus
768137 Danio rerio
140917 Mus musculus
Fournisseurs de qualité sélectionnés pour DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Protéines (DCLRE1B)
Avez-vous cherché autre chose?