anti-Dead End Homolog 1 (Zebrafish) (DND1) Anticorps

DND1 encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. De plus, nous expédions Dead End Homolog 1 (Zebrafish) Protéines (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DND1 213236 Q6VY05
DND1 373863 Q8IYX4
DND1 679841  
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Top anti-Dead End Homolog 1 (Zebrafish) Anticorps sur anticorps-enligne.fr

Showing 10 out of 39 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-DND1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate DND1 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit Anti-DND1 Antibody     Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue  Observed Staining: Cytoplasmic in pinealocytes  Primary Antibody Concentration: 1:100  Other Working Concentrations: 1/600  Secondary Antibody: Donkey anti-Rabbit-Cy3  Secondary Antibody Concentration: 1:200  Magnification: 20X  Exposure Time: 0.5 - 2.0 sec 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB Host:  Rabbit  Target Name:  Dnd1  Sample Type:  Rat Small Intestine lysates  Antibody Dilution:  1.0ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of DND1 Antibody  in Hela cell line lysates (35ug/lane).This demonstrates the DND1 antibody detected the DND1 protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Souris Inconjugué WB DND1 monoclonal antibody (M07), clone 2G11. Western Blot analysis of DND1 expression in NIH/3T3. 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Chien Lapin Inconjugué IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-DND1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. O ... 50 μg Connectez-vous pour afficher 11 to 14 Days
$727.83
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB DND1 Antibody (Center)  western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DND1 antibody detected the DND1 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Souris Inconjugué ELISA, WB DND1 monoclonal antibody (M07), clone 2G11 Western Blot analysis of DND1 expression in Hela S3 NE . DND1 monoclonal antibody (M07), clone 2G11. Western Blot analysis of DND1 expression in NIH/3T3 . 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué WB Western blot analysis in Hela cell line lysates (35ug/lane). 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails

Plus d’anticorps contre Dead End Homolog 1 (Zebrafish) partenaires d’interaction

Mouse (Murine) Dead End Homolog 1 (Zebrafish) (DND1) interaction partners

  1. DND1 binds a UU(A/U) trinucleotide motif predominantly in the 3' untranslated regions of mRNA, and destabilizes target mRNAs through direct recruitment of the CCR4 (Montrer CCR4 Anticorps)-NOT deadenylase complex.

  2. DND1 interacts with NANOS2 to load unique RNAs into the CCR4-NOTdeaden complex; this interaction is mediated by the zinc finger domain of NANOS2, which is essential for its association with target RNAs; DND1 is an essential partner for NANOS2 that leads to the degradation of specific RNAs in male germ cell development

  3. Dnd1 heterozygotes, lower oxygen availability was associated with metabolic differences

  4. APOBEC3G (Montrer APOBEC3G Anticorps) inhibits DND1 function to regulate microRNA activity.

  5. results show that Dnd1 is essential for normal allelic inheritance and that Dnd1Ter has a novel combination of functions that significantly increase risk for both testicular and intestinal cancer

  6. DND1 is the first protein known to have an RNA recognition motif directly implicated as a heritable cause of spontaneous tumorigenesis

  7. DND1-alpha isoform to be necessary for germ cell viability and its loss in Ter (Montrer TECR Anticorps) mice results in germ cell depletion, germ cell tumor development and partial embryonic lethality in the 129 strain.

  8. The role of dead-end in germ-cell tumor development.

  9. The interaction of DND1 and APOBEC3 could be one mechanism for maintaining viability of germ cells and for preventing germ cell tumor development

  10. when Dnd1(Ter/Ter) XX germ cells developed in a testicular environment they gave rise to the same neoplastic clusters as mutant XY germ cells in a testis.

Human Dead End Homolog 1 (Zebrafish) (DND1) interaction partners

  1. Mechanistically, Dnd1 could bind to 3'-UTR (Montrer UTS2R Anticorps) of LATS2, the key kinase of Hippo pathway, thus elevating LATS2 mRNA stability and its expression, subsequently leading to phosphorylation of YAP (Montrer YAP1 Anticorps) and its cytoplasmic retention.

  2. Dnd1 facilitates apoptosis by increasing the expression of Bim (Montrer BCL2L11 Anticorps) via its competitive combining with miR (Montrer MLXIP Anticorps)-221 in Bim-3'UTR (Montrer UTS2R Anticorps).

  3. RBM38 (Montrer RBM38 Anticorps) and DND1 are repressed in primary acute myeloid leukemia (Montrer BCL11A Anticorps), neutrophil differentiation is dependent on increased expression of both proteins, and they have a role in regulating p21(CIP1 (Montrer CDKN1A Anticorps)) expression during acute promyelocytic leukemia (Montrer PML Anticorps) differentiation

  4. APOBEC3G (Montrer APOBEC3G Anticorps) inhibits DND1 function to regulate microRNA activity.

  5. The increased sensitivity of transformed keratinocytes to miR (Montrer MLXIP Anticorps)-21's effects occurs in part through downregulation of the RNA-binding protein (Montrer PTBP1 Anticorps) DND1 during the transformation process.

  6. Results suggest that DND1 may impose another level of translational regulation to modulate expression of critical factors in ES cells.

  7. We conclude that germline DND1 mutations are unlikely to contribute significantly to human testicular germ cell tumor susceptibility

  8. Cloning of zebrafish dnd1 and identification of human DND1 by database analysis.

  9. Unravels a novel role of Dnd1 in protecting certain mRNAs from miRNA-mediated repression.

  10. MiR (Montrer MLXIP Anticorps)-24 up-regulation reduced the expression of RNA-binding protein (Montrer PTBP1 Anticorps) dead end 1 (Montrer VPS11 Anticorps) (DND1). Knockdown of miR (Montrer MLXIP Anticorps)-24 led to enhanced expression of DND1.

Dead End Homolog 1 (Zebrafish) (DND1) profil antigène

Profil protéine

This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.

Gene names and symbols associated with DND1

  • DND microRNA-mediated repression inhibitor 1 (dnd1) anticorps
  • dead end protein homolog 1 pseudogene (LOC100349427) anticorps
  • DND microRNA-mediated repression inhibitor 1 (DND1) anticorps
  • DND microRNA-mediated repression inhibitor 1 (Dnd1) anticorps
  • BC034897 anticorps
  • dead-end anticorps
  • dnd anticorps
  • DND1 anticorps
  • RBMS4 anticorps
  • Ter anticorps
  • xde anticorps
  • Xdead anticorps

Protein level used designations for DND1

dead end homolog 1 , dead end homolog 1 (zebrafish) , dead end protein homolog 1-like , dead end protein homolog 1 , RNA-binding motif, single-stranded-interacting protein 4 , teratoma

GENE ID SPECIES
733500 Xenopus (Silurana) tropicalis
100349427 Oryctolagus cuniculus
425270 Gallus gallus
462121 Pan troglodytes
100061778 Equus caballus
100441044 Pongo abelii
100604987 Nomascus leucogenys
607141 Canis lupus familiaris
525516 Bos taurus
213236 Mus musculus
373863 Homo sapiens
679841 Rattus norvegicus
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