anti-Decapping Enzyme, Scavenger (DCPS) Anticorps

Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. De plus, nous expédions Decapping Enzyme, Scavenger Protéines (9) et Decapping Enzyme, Scavenger Kits (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DCPS 28960 Q96C86
DCPS 69305 Q9DAR7
DCPS 266605 Q8K4F7
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Top anti-Decapping Enzyme, Scavenger Anticorps sur anticorps-enligne.fr

Showing 10 out of 46 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$522.50
Détails
Humain Souris Inconjugué ELISA, IF, IHC, IHC (p), WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$537.17
Détails
Humain Souris Inconjugué ELISA, IF, IHC, WB Immunofluorescence of monoclonal antibody to DCPS on HeLa cell (antibody concentration 10 µg/mL). DCPS monoclonal antibody (M02), clone 1G4 Western Blot analysis of DCPS expression in HeLa. 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Humain Souris Inconjugué ELISA, IHC, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (62.81 KDa) . Dilution: 1:500~1000 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Humain Souris Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$537.17
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué WB DCPS Antibody (Center)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DCPS antibody detected the DCPS protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué WB Western blot analysis in NCI-H460 cell line lysates (35ug/lane). 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué WB Western blot analysis of extract of HT-29 cells, using DCPS antibody. 100 μL Connectez-vous pour afficher 16 Days
$334.77
Détails
Humain Souris Inconjugué IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to DCPS on formalin-fixed paraffin-embedded human kidney. [antibody concentration 1.5 ug/ml] Immunofluorescence of monoclonal antibody to DCPS on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails

anti-Decapping Enzyme, Scavenger Anticorps mieux référencés

  1. Human Polyclonal DCPS Primary Antibody pour ICC, IF - ABIN4304527 : Ng, Shboul, Taverniti, Bonnard, Lee, Eskin, Nelson, Al-Raqad, Altawalbeh, Séraphin, Reversade: Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects. dans Human molecular genetics 2015 (PubMed)

Plus d’anticorps contre Decapping Enzyme, Scavenger partenaires d’interaction

Human Decapping Enzyme, Scavenger (DCPS) interaction partners

  1. Data show that decapping scavenger enzyme DcpS (DcpS) is a nucleocytoplasmic shuttling protein that activates microRNA (miRNA) degradation.

  2. In DcpS, conformational change is dominated by an anti-symmetric cooperative motion, causing one active site to close as the other opens; however a symmetric motion is also significant.

  3. In vitro decapping assays showed that altered EDC3 (Montrer EDC3 Anticorps) is unable to enhance DCP2 (Montrer DCP2 Anticorps) decapping at low concentrations and even inhibits DCP2 (Montrer DCP2 Anticorps) decapping at high concentration.

  4. DCPS and more generally RNA catabolism, are critical for neurological development, normal cognition and organismal homeostasis in humans.

  5. data demonstrate that DcpS in conjunction with Xrn1 (Montrer XRN1 Anticorps) has the potential to regulate RNA stability in a transcript-selective manner in mammalian cells

  6. The central histidine within the DcpS HIT motif is critical for decapping activity and defines the HIT motif as a new mRNA decapping domain, making DcpS the first member of the HIT family of proteins with a defined biological function.

  7. m7GDP breakdown by DcpS should prevent misincorporation of methylated nucleotides in nucleic acids and could generate a unique indicator allowing the cell to monitor mRNA decay.

  8. crystal structures of DcpS in ligand-free form and in a complex with m7GDP

  9. Furthermore, we show that a novel human histidine triad protein DCS-1, which is expressed together with NR1 in many tissues, can significantly reduce menadione-induced cytotoxicity in these cells

  10. These studies demonstrate that the significance of DcpS extends beyond its well-characterized role in mRNA decay and involves a broader range of functions in RNA processing including nuclear pre-mRNA splicing.

Mouse (Murine) Decapping Enzyme, Scavenger (DCPS) interaction partners

Decapping Enzyme, Scavenger (DCPS) profil antigène

Profil protéine

Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.

Gene names and symbols associated with DCPS

  • decapping enzyme, scavenger (DCPS) anticorps
  • decapping enzyme, scavenger (dcps) anticorps
  • decapping enzyme, scavenger (Dcps) anticorps
  • 1700001E16Rik anticorps
  • AA408441 anticorps
  • DCPS anticorps
  • DCS1 anticorps
  • Hint-5 anticorps
  • HINT5 anticorps
  • HSL1 anticorps

Protein level used designations for DCPS

decapping enzyme, scavenger , DCS-1 , decapping scavenger enzyme , heat shock-like protein 1 , hint-related 7meGMP-directed hydrolase , histidine triad nucleotide-binding protein 5 , histidine triad protein member 5 , homolog of C. elegans 7meGMP-directed hydrolase dcs-1 , m7GpppX diphosphatase , mRNA decapping enzyme , scavenger mRNA-decapping enzyme DcpS , HINT-5

GENE ID SPECIES
419716 Gallus gallus
609536 Canis lupus familiaris
100216298 Xenopus (Silurana) tropicalis
28960 Homo sapiens
69305 Mus musculus
266605 Rattus norvegicus
282640 Bos taurus
396689 Sus scrofa
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