anti-Defensin, alpha 4, Corticostatin (DEFA4) Anticorps

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. De plus, nous expédions Defensin, alpha 4, Corticostatin Kits (8) et Defensin, alpha 4, Corticostatin Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DEFA4 1669 P12838
DEFA4 13238 P28311
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Showing 10 out of 53 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Human Breast Cancer Tissue. 100 μg 13 to 16 Days
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of Defensin alpha4 using HuvEc whole cell lysates ABIN6278446 at 1/100 staining Mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
Humain Lapin Inconjugué IHC (p), WB Immunohistochemistry analysis of Defensin alpha 4 Antibody in paraffin-embedded human heart tissue. Western blot analysis of Defensin alpha 4 antibody at a 1/500 dilution. Lane 1: MCF-7 cell lysate. Lane 2: Mouse spleen tissue extract. Lane 3: Rat spleen tissue extract. 0.1 mg 6 to 8 Days
Humain Lapin Inconjugué ELISA, IHC   100 μL Disponible
Humain Lapin Inconjugué IF/ICC, IHC, IP, WB Western blot analysis of recombinant Human DEFa4. IHC-P analysis of Human Skin Cancer Tissue, with DAB staining. 100 μg 11 to 18 Days
Humain Lapin Inconjugué IHC, ELISA   100 μg 2 to 3 Days
Humain Lapin Inconjugué WB   100 μL 11 to 14 Days
Humain Lapin Inconjugué IHC, IHC (p), WB   50 μL 11 to 14 Days
Humain Lapin Inconjugué ELISA, IHC, IHC (p)   50 μL 11 to 14 Days
Humain Lapin Inconjugué IHC (p) Immunohistochemical analysis of paraffin-embedded human heart tissue using DEFA4 polyclonal antibody . 100 μL 11 to 12 Days

Plus d’anticorps contre Defensin, alpha 4, Corticostatin partenaires d’interaction

Human Defensin, alpha 4, Corticostatin (DEFA4) interaction partners

  1. DEFA4 displays antimicrobial activity against E. coli, S. faecalis, and C. albicans.

  2. Results indicate that the gene expression of DEFA 1/3 and 4 was significantly increased in all tumours - except for a significant decrease of DEFA 4 gene expression in pleomorphic adenomas.

  3. DEFA1-3 and DEFA4 mRNA level in peripheral blood cells can be used to identify chronic myeloid leukaemia patients who are at risk of being imatinib-resistant, before initiation of the therapy.

  4. The combination of an increased expression of the antimicrobial peptide DEFA-4, the oncogene S100-A7, epidermal growth factor, and tenascin-c, and a decreased Doc-1 expression in oral leukoplakia might characterize its potency of malignant transformation.

  5. Crystal structure of HNP-4.

  6. DEFA4 was upregulated in IPF patients with acute exacerbation

Rhesus Monkey Defensin, alpha 4, Corticostatin (DEFA4) interaction partners

  1. Lys-for-Arg substitutions in rhesus myeloid alpha-defensin improved microbicidal activity against certain bacteria

Mouse (Murine) Defensin, alpha 4, Corticostatin (DEFA4) interaction partners

  1. Depleting CRP4 is incompatible with a proper cardiac development and function. CRP4 is a novel antiremodeling factor regulated, at least to some extent, by cardiac cGMP.

  2. Backbone cyclization provides a means for engineeringalpha-defensins to improve their biological activity while providing excellent stability to serum degradation and highlighting the potential of peptide scaffolds for development of novel compounds.

  3. bactericidal activity predominantly affects noncommensal bacteria

  4. MMP-7-dependent procryptdin activation in vivo provides mouse Paneth cells with functional peptides for apical secretion into the small intestine lumen

  5. the prosegment of Crp4 inhibits Crp4 bactericidal activity by blocking peptide-mediated perturbation of target cell membranes

  6. Crp4 disulfide arrangement confers essential protection from degradation by this critical activating proteinase, allowing antibacterial action.

  7. cryptdin-1 and cryptdin-4 exhibit circadian oscillation

  8. function of the conserved salt bridge in Crp4 is not linked to bactericidal activity or proteolytic stability of the mature peptide.

  9. CRP4 mediates cGMP/PKG stimulation of SM-specific gene expression, and PKG plays an important role in regulating the phenotype of VSMCs

  10. Kinetics of Crp4 translocation coupled with peptide-induced vesicle leakage are reported.

  11. Beta-sheet-containing Crp4 induces membrane permeabilization more effectively than disulfide-null Crp4 by translocating and forming transient membrane defects.

  12. Lys-for-Arg replacements in cryptdin 4 attenuated bactericidal activity

Defensin, alpha 4, Corticostatin (DEFA4) profil antigène

Profil protéine

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils\; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production.

Gene names and symbols associated with DEFA4

  • defensin alpha 4 (DEFA4) anticorps
  • defensin, alpha 4, corticostatin (DEFA4) anticorps
  • defensin, alpha, 4 (Defa4) anticorps
  • Crp4 anticorps
  • DEF4 anticorps
  • DEFA4 anticorps
  • Defa28 anticorps
  • Defcr4 anticorps
  • HNP-4 anticorps
  • HP-4 anticorps
  • HP4 anticorps

Protein level used designations for DEFA4

corticostatin , defensin, alpha 4, preproprotein , neutrophil defensin 4 , alpha-defensin 4, corticostatin , Paneth cell-specific alpha-defensin 4 , alpha-defensin 4 , alpha-defensin, 28 , defensin related cryptdin 4 , defensin, alpha, 28 , defensin-related cryptdin-4

1669 Homo sapiens
463971 Pan troglodytes
574311 Macaca mulatta
100307026 Equus caballus
13238 Mus musculus
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