anti-Defensin, alpha 5, Paneth Cell-Specific (DEFA5) Anticorps

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. De plus, nous expédions Defensin, alpha 5, Paneth Cell-Specific Kits (54) et Defensin, alpha 5, Paneth Cell-Specific Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DEFA5 1670 Q01523
DEFA5 13239  
DEFA5 286995 Q62715
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Top anti-Defensin, alpha 5, Paneth Cell-Specific Anticorps sur anticorps-enligne.fr

Showing 10 out of 57 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué DB, ICC, FACS, IF, IHC (p), IHC, ELISA, WB Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining using ABIN258712. Flow Cytometry: Defensin alpha 5 Antibody (8C8) [ABIN2587122] - Intracellular flow cytometric staining of 1 x 10^6 MCF-7 cells using Defensin alpha 5 antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$408.19
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Immunohistochemistry-Paraffin: Defensin alpha 5 Antibody [NBP1-84282] - Staining of human small intestine shows strong cytoplasmic positivity in Paneth cells. Immunohistochemistry-Paraffin: Defensin alpha 5 Antibody [NBP1-84282] - Staining of human nasopharynx shows cytoplasmic and membranous positivity in respiratory epithelial cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$439.69
Détails
Humain Souris Inconjugué IF, IHC (p), WB Human Small Intestine (formalin-fixed, paraffin-embedded) stained with DEFA5 antibody ABIN396940 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μL Connectez-vous pour afficher 7 to 9 Days
$595.83
Détails
Humain Lapin Inconjugué ICC, IHC, IP, WB 100 μg Connectez-vous pour afficher 15 to 18 Days
$332.00
Détails
Humain Souris Inconjugué ICC, IHC (fro), IHC (p), ELISA, WB 200 μg Connectez-vous pour afficher 13 to 16 Days
$352.00
Détails
Humain Souris Inconjugué IF, IHC (p), WB 100 μL Connectez-vous pour afficher 6 to 7 Days
$506.80
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB   100 μL Connectez-vous pour afficher 14 to 21 Days
$295.90
Détails
Humain Lapin Inconjugué WB   100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Alexa Fluor 647 ELISA, FACS, ICC, IF, IHC, IHC (p), WB   0.1 mL Connectez-vous pour afficher 7 to 9 Days
$500.06
Détails
Humain Souris Biotin ELISA, ICC, IF, IHC, IHC (p), WB   0.1 mL Connectez-vous pour afficher 7 to 9 Days
$500.06
Détails

DEFA5 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , , , ,
,
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, , , , , , , , , , , , , , , ,
Mouse (Murine)


Rat (Rattus)


anti-Defensin, alpha 5, Paneth Cell-Specific Anticorps mieux référencés

  1. Human Monoclonal DEFA5 Primary Antibody pour DB, ICC - ABIN258712 : Wehkamp, Salzman, Porter, Nuding, Weichenthal, Petras, Shen, Schaeffeler, Schwab, Linzmeier, Feathers, Chu, Lima, Fellermann, Ganz, Stange, Bevins: Reduced Paneth cell alpha-defensins in ileal Crohn's disease. dans Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 9 Pubmed References

  2. Human Monoclonal DEFA5 Primary Antibody pour IA, IHC (fro) - ABIN2192079 : Kelly, Bajaj-Elliott, Katubulushi, Zulu, Poulsom, Feldman, Bevins, Dhaliwal: Reduced gene expression of intestinal alpha-defensins predicts diarrhea in a cohort of African adults. dans The Journal of infectious diseases 2006 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal DEFA5 Primary Antibody pour IHC, IHC (p) - ABIN4304804 : Lee, Nam, Park, Kim, Lafleur, Aburatani, Yang, Kim, Goldenring: Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer. dans Gastroenterology 2010 (PubMed)

Plus d’anticorps contre Defensin, alpha 5, Paneth Cell-Specific partenaires d’interaction

Human Defensin, alpha 5, Paneth Cell-Specific (DEFA5) interaction partners

  1. Human alpha-Defensin-5 is a potential candidate biomarker to molecularly differentiate Crohn's colitis from ulcerative colitis, to our knowledge. These data give us both a potential diagnostic marker in Human alpha-Defensin-5 and insight to develop future mechanistic studies to better understand crypt biology in Crohn's colitis.

  2. Different dynamics and pathway of disulfide bonds reduction has been demonstrated for two human defensins, HD5 and HBD-3 (Montrer DEFB103A Anticorps).

  3. Human adenovirus 3 produces large amounts of penton-dodecahedra (PtDd), virus-like particles, during replication, which also function in blocking of HD5.

  4. no biologic differences between wild-type HD5 and its variants were observed on HD5 antibacterial activity against Escherichia coli

  5. a moderately active linear peptide derived from the alpha-defensin (Montrer DEF Anticorps) HD5 can be engineered to enhance antimicrobial activity almost comparable to the native peptide.

  6. The study used ion mobility coupled to mass spectrometry to track the structural changes in HD-5 upon disulfide bond reduction.

  7. The study reports the screening of human defensin 5 against the Keio Collection of E. coli strains and shows how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.

  8. Authors show that although NOD2 (Montrer NOD2 Anticorps) by itself can slightly up-regulate expression of HD5 and HD6 (Montrer DEFA6 Anticorps), it can strongly down-regulates their expression during differentiation of the Paneth cell lineage mainly by inhibiting activation of the MAPK (Montrer MAPK1 Anticorps) pathway.

  9. These data support a model in which HD5 prevents furin (Montrer FURIN Anticorps) from accessing human papillomavirus 16 L2 by occluding the furin (Montrer FURIN Anticorps) cleavage site via direct binding to the viral capsid.

  10. Enteric alpha-defensin (Montrer DEF Anticorps) HD5 and beta-defensin (Montrer DEFB1 Anticorps) hBD2 (Montrer DEFB4 Anticorps) shared similar toxin-unfolding effects with HNP1 (Montrer DEFA1 Anticorps), albeit to different degrees.

Mouse (Murine) Defensin, alpha 5, Paneth Cell-Specific (DEFA5) interaction partners

  1. alpha-defensin 5 expression can also be regulated by microbial metabolites

  2. Data show that DEFA5-expressing mice had striking losses of segmented filamentous bacteria and fewer interleukin 17 (IL-17 (Montrer IL17A Anticorps))-producing lamina propria T cells.

Defensin, alpha 5, Paneth Cell-Specific (DEFA5) profil antigène

Profil protéine

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

Gene names and symbols associated with DEFA5

  • defensin alpha 5 (DEFA5) anticorps
  • defensin, alpha, 5 (Defa5) anticorps
  • defensin, alpha 5, Paneth cell-specific (DEFA5) anticorps
  • defensin alpha 5 (Defa5) anticorps
  • DEF5 anticorps
  • Defa anticorps
  • DEFA1 anticorps
  • DEFA5 anticorps
  • Defa29 anticorps
  • Defcr5 anticorps
  • Defcr29 anticorps
  • HD-5 anticorps

Protein level used designations for DEFA5

HD5(20-94) , defensin 5 , defensin, alpha 5, preproprotein , defensin-5 , alpha-defensin 5 , defensin, alpha, 29 , defensin-related cryptdin-5 , alpha-defensin 5, Paneth cell-specific , defensin, alpha 1 , Paneth cell-specific alpha-defensin 5 , defensin NP-2 , neutrophil antibiotic peptide NP-1 , neutrophil antibiotic peptide NP-2 , neutrophil defensin 1 , neutrophil defensin 2 , ratNP-1 , ratNP-2

GENE ID SPECIES
1670 Homo sapiens
13239 Mus musculus
463972 Pan troglodytes
100307028 Equus caballus
286995 Rattus norvegicus
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