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Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000. De plus, nous expédions Dehydrogenase/reductase (SDR Family) Member 3 Protéines (4) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal DHRS3 Primary Antibody pour ICC, IF - ABIN4305162
Deisenroth, Itahana, Tollini, Jin, Zhang: p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation. dans The Journal of biological chemistry 2011
dhrs3 participates in atRA metabolism by reducing atRAL levels and is required for proper anteroposterior axis formation, neuroectoderm patterning, and somitogenesis.
Data show that dhrs3 was activated at the onset of gastrulation, and remained highly expressed at later stages of embryonic development.
Dhrs3a is thus an retinoic acid (RA)-induced feedback inhibitor of RA biosynthesis.
the bifunctional nature of retinoid oxidoreductase (Montrer TXNRD1 Anticorps) complex provides the RA-based signaling system with robustness by safeguarding appropriate RA concentration despite naturally occurring fluctuations in RDH10 (Montrer RDH10 Anticorps) and DHRS3.
Data indicate that retinaldehyde reductase (DHRS3) requires retinol dehydrogenase 10 (RDH10 (Montrer RDH10 Anticorps)) for full enzymatic activity and, in turn, activates RDH10 (Montrer RDH10 Anticorps).
p53 (Montrer TP53 Anticorps)-Inducible DHRS3 is an endoplasmic reticulum protein (Montrer PDIA3 Anticorps) associated with lipid droplet accumulation.
The retSDR1 is identified as novel transcriptional target of the p53 (Montrer TP53 Anticorps) family and not transactivated by EEC syndrome-specific mutations of TAp63gamma.
CST6 (Montrer CST6 Anticorps), CXCL14 (Montrer CXCL14 Anticorps), DHRS3, and SPP1 (Montrer SPP1 Anticorps) are regulated by BRAF (Montrer BRAF Anticorps) signaling and may play a role in papillary thyroid carcinoma pathogenesis
Reduction of retinaldehyde by DHRS3 is critical for preventing formation of excess ATRA during embryonic development.
Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000
short-chain dehydrogenase/reductase 3
, dehydrogenase/reductase 3
, dehydrogenase/reductase (SDR family) member 3
, retinal short-chain dehydrogenase/reductase 1
, short chain dehydrogenase/reductase family 16C, member 1
, short-chain dehydrogenase/reductase 1
, retinal dehydrogenase/reductase family member 3