Profil protéine

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications\\\\; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat\\\\; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified\\\\; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat.

Gene names and symbols associated with DAZ3

• deleted in azoospermia 3 (DAZ3) anticorps
• deleted in azoospermia protein 3 (LOC738636) anticorps

• DAZ2 anticorps
• DAZ3 anticorps
• pDP1679 anticorps

Protein level used designations for DAZ3

deleted in azoospermia protein 3 , deleted in azoospermia 3 , deleted in azoospermia 4