Diacylglycerol Kinase, beta 90kDa Protéines (DGKB)

Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. De plus, nous expédions Diacylglycerol Kinase, beta 90kDa Anticorps (46) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
DGKB 217480 Q6NS52
Rat DGKB DGKB 54248 P49621
DGKB 1607 Q9Y6T7
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Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
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Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
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HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
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DGKB Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human ,
,

Plus protéines pour Diacylglycerol Kinase, beta 90kDa (DGKB) partenaires d'interaction

Mouse (Murine) Diacylglycerol Kinase, beta 90kDa (DGKB) interaction partners

  1. Memantine, an NMDA receptor antagonist, improves working memory deficits in Diacylglycerol kinase (DGK) beta knockout mice. These findings may support the hypothesis that DGKbeta has a pivotal role in cognitive function.

  2. These findings suggest that DGKbeta regulates the spine formation at distal dendrites in medium spiny neurons

  3. This study demonistrated that Dgkb distribuate in mice cerebellum

  4. forced expression of diacylglycerol kinase beta abrogated DAG accumulation at the phagosome, leading to impaired respiratory burst.

  5. that DGKbeta KO mice showed attention-deficit and hyperactive phenotype, similar to ADHD.

  6. Results demonstrate that membrane-localized DGKbeta regulates spine formation by regulation of lipids, contributing to the maintenance of neural networks in synaptic transmission of cognitive processes including memory.

Human Diacylglycerol Kinase, beta 90kDa (DGKB) interaction partners

  1. Association with the efficiency of hematopoietic stem cells (HSC (Montrer FUT1 Protéines)) mobilization to PB were found in the SNPs of the DGKB gene involved in cell transport and SDF-1 (Montrer CXCL12 Protéines)-induced migration ability and of the VCAM1 (Montrer VCAM1 Protéines) gene which is essential for HSC (Montrer FUT1 Protéines) homing, suggesting that SNPs involved in cell migration ability might be partly involved in HSC (Montrer FUT1 Protéines) mobilization to peripheral blood.

  2. in addition to kinase activity, plasma membrane localization via the C1 domain and basic amino acids at the C-terminus were indispensable for neurite induction by DGKbeta

  3. forced expression of diacylglycerol kinase beta abrogated DAG accumulation at the phagosome, leading to impaired respiratory burst.

  4. findings further suggest that DGL-alpha (Montrer DAGLA Protéines) and -beta may regulate neurite outgrowth by engaging temporally and spatially distinct molecular pathways

  5. human diacylglycerol kinase beta gene can generate several enzyme isoforms, which can display different expression levels and subcellular localization but similar enzymatic activities in vitro.

  6. Indicates that this protein can interact with keratin 31 and with protocadherin beta 5 (Montrer PCDHb5 Protéines).

Profil protéine Diacylglycerol Kinase, beta 90kDa (DGKB)

Profil protéine

Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with DGKB

  • diacylglycerol kinase beta (DGKB)
  • diacylglycerol kinase beta (dgkb)
  • diacylglycerol kinase, beta (Dgkb)
  • 90kda Protéine
  • 6430574F24 Protéine
  • C630029D13Rik Protéine
  • Dagk Protéine
  • DAGK2 Protéine
  • DGK Protéine
  • DGK-BETA Protéine
  • MGC122563 Protéine
  • mKIAA0718 Protéine

Protein level used designations for DGKB

diacylglycerol kinase, beta 90kDa , diacylglycerol kinase beta , diacylglycerol kinase, beta-like , diacylglycerol kinase beta-like , DAG kinase beta , diglyceride kinase beta , 90 kDa diacylglycerol kinase , DGK-beta , Diacylglycerol kinase 90kDa , diacylglycerol kinase beta, 90kDa

GENE ID SPECIES
463271 Pan troglodytes
537171 Bos taurus
772367 Gallus gallus
100052717 Equus caballus
100124765 Xenopus (Silurana) tropicalis
100355585 Oryctolagus cuniculus
100394266 Callithrix jacchus
100556056 Anolis carolinensis
100625799 Sus scrofa
217480 Mus musculus
54248 Rattus norvegicus
1607 Homo sapiens
482328 Canis lupus familiaris
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