Dihydropyrimidinase-Like 5 (DPYSL5) Kits ELISA

DPYSL5 encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. De plus, nous expédions Dihydropyrimidinase-Like 5 Anticorps (51) et Dihydropyrimidinase-Like 5 Protéines (8) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
DPYSL5 56896 Q9BPU6
DPYSL5 65208 Q9JHU0
DPYSL5 65254 Q9EQF6
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Souris 1.0 ng/mL 5.0-100 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
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Humain 1.0 ng/mL 5.0-100 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
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Plus Kits ELISA pour Dihydropyrimidinase-Like 5 partenaires d'interaction

Human Dihydropyrimidinase-Like 5 (DPYSL5) interaction partners

  1. Study describes the relevance of DRP5 during osteosarcoma development. DRP5 was upregulated in osteosarcoma specimens and cell lines and shown to function via the downstream MMPs. Inhibition of DRP5 suppressed the growth of cancer cells in vitro and in vivo, and high expression levels of DRP5 were associated with poor prognosis in osteosarcoma patients.

  2. Our findings suggest that CRMP5 serves as a major mediator of Notch (Montrer NOTCH1 Kits ELISA) signaling and Akt (Montrer AKT1 Kits ELISA) activation by controlling the degradation of the Notch (Montrer NOTCH1 Kits ELISA) receptor, with implications for defining a biomarker signature in glioblastoma

  3. present study suggested that CRAM (Montrer CCRL2 Kits ELISA) could be a clinical prognostic marker for patients with cervical cancer

  4. study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.

  5. identified residues that are crucial for determining the preference for hetero-oligomer or homo-oligomer formation. In spite of being the CRMP family member most closely related to dihydropyrimidinase (Montrer DPYS Kits ELISA), CRMP-5 does not have amidohydrolase activity.

  6. New CRMP5 isoform present in the nucleus is associated with Glioma.

  7. CRMP-5-IgG defines a paraneoplastic ophthalmological entity of combined optic neuritis and retinitis with vitreous inflammatory cells.

  8. CRMP-5 autoimmune myelopathy and occult neoplasia are important considerations in patients with insidiously progressive myelopathy, especially with known cancer risk.

  9. We describe a patient with optic neuropathy and vitritis as the only clinical manifestations of paraneoplastic optic neuropathy secondary to lung cancer marked by an extremely high titer of CRMP-5 antibody.

  10. findings point at CRMP5 as a novel marker for distinguishing between highly aggressive neuroendocrine carcinoma and the other lung cancers.

Mouse (Murine) Dihydropyrimidinase-Like 5 (DPYSL5) interaction partners

  1. study elucidates a novel regulatory mechanism that utilizes CRMP5-induced mitophagy to orchestrate proper dendrite outgrowth and neuronal function.

  2. CRMP5-deficient mice show abnormal Schwann process extension resulting in abnormal cell-axon segregation, indicating that CRMP5 is involved in the morphologic adaptation of Schwann cells to surround axons.

  3. These findings provide the first evidence that CRMP5 is involved in the generation and survival of newly generated neurons in areas of the adult brain with a high level of activity-dependent neuronal plasticity.

  4. Data show that CRMP5 is involved in the development, maintenance and synaptic plasticity of Purkinje cells.

  5. The CRMP5 binding to tubulin (Montrer TUBB Kits ELISA) modulates CRMP2 (Montrer DPYSL2 Kits ELISA) regulation of neurite outgrowth and neuronal polarity during brain development.

  6. CRAM regulates filopodial dynamics and growth cone development, thereby restricting the response of growth cone to repulsive guidance cues

  7. In the olfactory bulb, CRMP1 (Montrer CRMP1 Kits ELISA), CRMP2 (Montrer DPYSL2 Kits ELISA) and CRMP5 are abundant in neuronal progenitors of the subependymal layer and in differentiating interneurons.

  8. Our results are therefore consistent with a role for CRMP5 in neuronal process extension.We conclude that expression of CRMP5 is consistent with a dynamic implicit role in forebrain development.

  9. Hypoxia-ischemia (HI)induces dephosphorylation of CRMPs (CRMP1 (Montrer CRMP1 Kits ELISA), 2, and 5) in neonatal brain. Hypophosphorylated CRMPs might be implicated in the pathogenesis of HI-related neurological disorders.

Dihydropyrimidinase-Like 5 (DPYSL5) profil antigène

Antigen Summary

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with DPYSL5

  • dihydropyrimidinase like 5 (DPYSL5) anticorps
  • dihydropyrimidinase-like 5 (Dpysl5) anticorps
  • Dihydropyrimidinase-related protein 5 (dpyl5) anticorps
  • dihydropyrimidinase-like 5a (dpysl5a) anticorps
  • dihydropyrimidinase like 5 (dpysl5) anticorps
  • dihydropyrimidinase like 5 (Dpysl5) anticorps
  • dihydropyrimidinase-like 5b (dpysl5b) anticorps
  • CRAM anticorps
  • CRMP-5 anticorps
  • CRMP-5a anticorps
  • CRMP-5b anticorps
  • Crmp5 anticorps
  • crmp5.1 anticorps
  • crmp5.2 anticorps
  • DPYSL5 anticorps
  • fc28b06 anticorps
  • im:7146614 anticorps
  • si:ch211-152c2.6 anticorps
  • Ulip6 anticorps
  • wu:fc28b06 anticorps

Protein level used designations for DPYSL5

CRMP3-associated molecule , DRP-5 , ULIP-6 , UNC33-like phosphoprotein 6 , collapsin response mediator protein 5 , collapsin response mediator protein-5 , dihydropyrimidinase-related protein 5 , dihydropyrimidinase-like 5 , Dihydropyrimidinase-related protein 5 , dihydropyrimidinase-related protein 5-like , collapsin response mediator protein 5.2

GENE ID SPECIES
56896 Homo sapiens
65208 Rattus norvegicus
65254 Mus musculus
483004 Canis lupus familiaris
699648 Macaca mulatta
100126171 Bos taurus
100196759 Salmo salar
100353506 Oryctolagus cuniculus
324416 Danio rerio
100030914 Monodelphis domestica
100071300 Equus caballus
100386950 Callithrix jacchus
100478389 Ailuropoda melanoleuca
100496348 Xenopus (Silurana) tropicalis
100511810 Sus scrofa
100558703 Anolis carolinensis
100598354 Nomascus leucogenys
100725488 Cavia porcellus
553410 Danio rerio
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