Dimethylarginine Dimethylaminohydrolase 2 Protéines (DDAH2)

DDAH2 belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. De plus, nous expédions DDAH2 Anticorps (61) et DDAH2 Kits (30) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
DDAH2 23564 O95865
DDAH2 51793 Q99LD8
DDAH2 294239 Q6MG60
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Showing 6 out of 7 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,749.58
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,749.58
Détails
Escherichia coli (E. coli) Humain His tag,T7 tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$669.00
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Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$338.33
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Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,750.00
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Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,750.00
Détails

DDAH2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Plus protéines pour Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) partenaires d'interaction

Human Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) interaction partners

  1. genetic variations in the DDAH2 gene may influence the ADMA concentration and erythropoietin resistance in MHD patients

  2. The main finding from this study was that it demonstrated that the C-allele of rs3087894 in DDAH1 is a risk factor for hypertension in the Kazakh group but a protective factor in the Uygur group. In addition, we did not find any genotype of DDAH1 and DDAH2 associated with hypertension in the Han group.

  3. Exogenous human DDAH2 gene promotes differentiation of rabbit bone marrow-derived endothelial progenitor cells into mature endothelial cells.

  4. expression of DDAH2 is associated with invasiveness of lung adenocarcinoma via tumor angiogenesis

  5. Inhibiting the expression of DDAH1, but not DDAH2, resulted in a significant increase in the sensitivity of the EVT cell line SGHPL-4 to tumour necrosis factor related apoptosis inducing ligand (TRAIL) induced apoptosis

  6. increased ADMA levels in rheumatoid arthritis do not appear to relate to DDAH genetic polymorphisms

  7. The percentage of senescent endothelial progenitor cells increased while the expression of DDAH2 decreased concomitantly with an increase in the plasma levels of asymmetric dimethylarginine in patients with type 2 diabetes mellitus.

  8. DDAH-1 is a specific molecular target for portal pressure reduction, through actions on ADMA-mediated regulation of eNOS activity.

  9. Our results suggest that the rs805304 C allele of the DDAH gene was associated with decreased risk of myocardial infarction and decreased risk of obesity.

  10. Homocysteine disrupts EPCs function via inducing the hypermethylation of DDAH2 promoter, suggesting a key role of epigenetic mechanism in the progression of atherosclerosis

  11. -476 to -469 of the DDAH2 promoter was a NF-kB responsive element and is important for the transactivation of DDAH2.

  12. The rs9267551 functional variant of the DDAH2 gene is associated with chronic kidney disease with carriers of the C allele having a lower risk of renal dysfunction independently from several confounders

  13. Our approaches revealed signature candidates of differentially hypermethylated genes of DDAH2 and DUSP1 which can be further developed as potential biomarkers for OSCC as diagnostic, prognostic and therapeutic targets in the future.

  14. Enhancing pulmonary DDAH II activity attenuates LPS-mediated lung leak in acute lung injury.

  15. There is a significant difference in distribution of DDAH2 gene polymorphism among hemodialysis patients compared to healthy individuals.

  16. DDAH2-1151 A/C polymorphism is associated with Chronic renal impairment in type 2 diabetes.

  17. Glucose-stimulated insulin secretion is increased in Ddah2-transgenic pancreatic islets by 33%, compared to its levels in wild-type mice.

  18. Suppression of DDAH2 expression is a culprit for homocysteine-induced impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells.

  19. Found that SNP rs2272592 in DDAH2 is associated with type 2 diabetes but SNP rs805304 in DDAH2 is not. DDAH2 SNP rs2272592 AG+GG genotypes are associated with genetic susceptibility to type 2 diabetes in Korean population.

  20. No association was observed between the DDAH2 polymorphisms at rs805305 and rs2272592 and coronary heart disease.

Mouse (Murine) Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) interaction partners

  1. We conclude that pp60(Src) can directly inhibit DDAH II and this is involved in the increased ADMA levels that enhance eNOS uncoupling during the development of acute lung injury (ALI).

  2. In mild CKD, dysregulation of the ADMA/DDAH pathway in adipose tissue triggers lipodystrophy-like phenotype changes, including ectopic fat depositions.

  3. The Sirt1/DDAH2/secretagogin pathway is a novel regulator of glucose-stimulated insulin secretion.

  4. DDAH2/ADMA pathway can be a novel therapeutic target for vasculopathy in the ADMA or angiotensin II-induced pathophysiological conditions

  5. Report tissue-specific downregulation of DDAH2 in hyperhomocysteinemia.

  6. Results show that asymmetric methylarginine increases pulmonary endothelial permeability, and that its effects on permeability, Rac1 activation and VASP phosphorylation are prevented by overexpression of active DDAHI and DDAHII.

  7. ADMA and nitrosative stress are related to increased expression of protein-arginine methyltransferase-2, an ADMA-synthesizing enzyme, and reduced expression of dimethylarginine dimethylaminohydrolase-2, an ADMA-degrading enzyme, in bronchial epithelia

Profil protéine DDAH2

Profil protéine

This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity.

Gene names and symbols associated with DDAH2

  • dimethylarginine dimethylaminohydrolase 2 (ddah2)
  • dimethylarginine dimethylaminohydrolase 2 L homeolog (ddah2.L)
  • dimethylarginine dimethylaminohydrolase 2 (DDAH2)
  • dimethylarginine dimethylaminohydrolase 2 (Ddah2)
  • 1110003M04Rik Protéine
  • AU019324 Protéine
  • AW413173 Protéine
  • Ddah Protéine
  • DDAH-2 Protéine
  • DDAH2 Protéine
  • DDAHII Protéine
  • G6a Protéine
  • MGC84290 Protéine
  • MGC89103 Protéine
  • NG30 Protéine

Protein level used designations for DDAH2

NG,NG-dimethylarginine dimethylaminohydrolase 2 , dimethylarginine dimethylaminohydrolase 2 , DDAH-2 , N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 , NG-dimethylarginine dimethylamino hydrolase homolog , S-phase protein , alternative name: NG30, G6a , dimethylargininase-2 , dimethylarginine dimethylaminohydrolase II , protein G6a , Clone 7u , DDAHII

GENE ID SPECIES
100194775 Salmo salar
447573 Xenopus laevis
448306 Xenopus (Silurana) tropicalis
716356 Macaca mulatta
745121 Pan troglodytes
23564 Homo sapiens
51793 Mus musculus
474846 Canis lupus familiaris
540386 Bos taurus
294239 Rattus norvegicus
100720724 Cavia porcellus
100352259 Oryctolagus cuniculus
101118391 Ovis aries
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