anti-Disabled Homolog 1 (Drosophila) (DAB1) Anticorps

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. De plus, nous expédions DAB1 Kits (22) et DAB1 Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DAB1 1600 O75553
DAB1 13131 P97318
DAB1 266729 Q8CJH2
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Top anti-DAB1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 148 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-DAB1 Antibody Titration: 0.2-1 ug/mlPositive Control: THP-1 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Poulet Lapin Inconjugué IC, IF, WB Immunofluorescent analysis of DAB1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of DAB1 expression in MCF7 (A), HEK293T (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IF, ELISA, WB Western blot analysis of extracts from HepG2/293 cells, using Dab1 (Ab-232) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of MCF7 cells, using Dab1 (Ab-232) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué IF, ELISA, WB Western blot analysis of extracts from HeLa cells, using Dab1 (Ab-220) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using Dab1 (Ab-220) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from LOVO cells, using Dab1 (Phospho-Tyr232) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: DAB1 Antibody [NBP2-16095] - Sample: HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: DAB1 protein stained by DAB1 antibody [N1N3] diluted at 1:500. Blue: Hoechst 33342 staining. Immunohistochemistry-Paraffin: DAB1 Antibody [NBP2-16095] - Immunohistochemical analysis of paraffin-embedded hela xenograft, using antibody at 1:500 dilution. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of DAB1 Antibody (Center) (ABIN652935) in mouse brain tissue lysates (35 µg/lane). DAB1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with DAB1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué ELISA, IF, WB 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Humain Lapin Inconjugué ELISA, IF, WB Western Blot (WB) analysis of specific cells using Dab1 Polyclonal Antibody. 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, IHC (p), WB Human Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails

anti-DAB1 Anticorps mieux référencés

  1. Human Polyclonal DAB1 Primary Antibody pour IHC - ABIN965969 : Chen, Ochalski, Tran, Sahir, Schubert, Pramatarova, Howell: Interaction between Dab1 and CrkII is promoted by Reelin signaling. dans Journal of cell science 2004 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal DAB1 Primary Antibody pour ELISA, ICC - ABIN6256680 : Liu, Li, Shu, Xiao, Feng: Ephrin‑b3 modulates hippocampal neurogenesis and the reelin signaling pathway in a pilocarpine‑induced model of epilepsy. dans International journal of molecular medicine 2018 (PubMed)

Plus d’anticorps contre DAB1 partenaires d’interaction

Human Disabled Homolog 1 (Drosophila) (DAB1) interaction partners

  1. In intestine a truncated Dab1 variant transmits the reelin (Montrer RELN Anticorps) signal and may play a role in clathrin-mediated apical endocytosis and in the control of cell-to-cell junction assembly. Dab1 variant may be a nucleocytoplasmic shuttling protein, inferred from its sequence and nuclear location.

  2. these results establish an unstable repeat insertion in DAB1 as a cause of cerebellar degeneration.

  3. Study shows that early neural cells transiently express Reelin (Montrer RELN Anticorps) at the time they leave the presumptive olfactory/vomeronasal epithelium and that Dab 1 is present in the migratory cell mass and in the presumptive ensheathing cells in the absence of reelin (Montrer RELN Anticorps).

  4. this study is the first to provide genetic evidence for DAB1 as a candidate AD liability/protection gene, although the strength of the contribution of DAB1 may differ among populations

  5. results of this study demonstrated the presence of reelin (Montrer RELN Anticorps), its receptors VLDLR (Montrer VLDLR Anticorps) and ApoER2 (Montrer LRP8 Anticorps) as well as Dab1 in the ENS and might indicate a novel role of the reelin (Montrer RELN Anticorps) system in regulating neuronal plasticity and pre-synaptic functions in the ENS.

  6. The finding of this study suggested that variations in DAB1 involved in the Reelin signaling pathway might contribute to genetic susceptibility to autism with Chinese Han decent.

  7. Variation in genes encoding proteins at the gateway of Reelin (Montrer RELN Anticorps) signaling: ligands RELN (Montrer RELN Anticorps) and APOE (Montrer APOE Anticorps), their common receptors APOER2 (Montrer LRP8 Anticorps) and VLDLR (Montrer VLDLR Anticorps), and adaptor DAB1, was examined.

  8. show that Reelin (Montrer RELN Anticorps)-stimulated Notch-1 (Montrer NOTCH1 Anticorps) activation is dependent on Reelin (Montrer RELN Anticorps) signaling

  9. alternative splicing of Dab1 is conserved in avian and mammalian species, with Dab1-L driving SFK phosphorylation in both species

  10. we report for the first time, that DAB1 is significantly up-regulated in human frontal cortex brain samples of Alzheimer disease patients

Mouse (Murine) Disabled Homolog 1 (Drosophila) (DAB1) interaction partners

  1. In intestine a truncated Dab1 variant transmits the reelin (Montrer RELN Anticorps) signal and may play a role in clathrin-mediated apical endocytosis and in the control of cell-to-cell junction assembly. Dab1 variant may be a nucleocytoplasmic shuttling protein, inferred from its sequence and nuclear location.

  2. These observations suggest that the morphogenesis in these hippocampal formation subdivisions employs different developmental mechanisms involving Dab1 function.

  3. These results suggest that deficiency of Reelin (Montrer RELN Anticorps)-Dab1 signal in the dorsal forebrain is involved in the pathogenesis of some symptoms of human psychiatric disorders.

  4. RBX2 (Montrer RNF7 Anticorps), a core component of the E3 ubiquitin ligase (Montrer MUL1 Anticorps) CRL5, is essential for retinal layering and function. RBX2 (Montrer RNF7 Anticorps) regulates the final cell position of rod bipolar cells, cone photoreceptors and Muller glia. Our data indicate that sustained RELN (Montrer RELN Anticorps)/DAB1 signaling, triggered by depletion of RBX2 (Montrer RNF7 Anticorps) or SOCS7 (Montrer SOCS7 Anticorps) - a CRL5 substrate adaptor known to recruit DAB1 - causes rod bipolar cell misposition.

  5. Mice with low or no Dab1 expression exhibited reduced calling rates, altered call-type usage, and differential vocal development trajectories.

  6. Results showed that the Dab1 nuclear localization signal mutant can translocate into the nucleus via an unconventional temperature-dependent/ATP-dependent and cytoplasmic soluble factor-independent/RanGTP gradient-independent manner, suggesting that Dab1 has 2 (Montrer HAS2 Anticorps) different nuclear translocation pathways; and that the regulation of subcellular localization of Dab1 is important for the proper migration of excitatory neurons.

  7. This study showed that spontaneous Dab1 mutations causing cerebellar pathology are impaired in motor functions during the neonatal period.

  8. an aberrant fragment of Dab1 protein (p64 (Montrer IL2RG Anticorps)/60) is present in the brain of yotari mouse

  9. When pregnant mice are exposed to EMF, Dab1 expression increases in the EMF-treated fetal cerebral cortex extracts as compared to controls and SHAM group.

  10. It findings link reelin (Montrer RELN Anticorps) with Dab1 and suggest that Dab1 functions downstream of reelin (Montrer RELN Anticorps) action on the homeostasis of the crypt-villus unit.

Pig (Porcine) Disabled Homolog 1 (Drosophila) (DAB1) interaction partners

  1. Alternative spliced forms of disabled homolog 1 (DAB1) have been isolated from brain and liver.

Zebrafish Disabled Homolog 1 (Drosophila) (DAB1) interaction partners

  1. Alternatively spliced dab1 isoforms were identified.

DAB1 profil antigène

Profil protéine

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Gene names and symbols associated with DAB1

  • DAB1, reelin adaptor protein (DAB1) anticorps
  • disabled 1 (Dab1) anticorps
  • DAB1, reelin adaptor protein (Dab1) anticorps
  • disabled homolog 1 (LOC100232823) anticorps
  • Dab, reelin signal transducer, homolog 1a (Drosophila) (dab1a) anticorps
  • Dab, reelin signal transducer, homolog 1b (Drosophila) (dab1b) anticorps
  • AI956902 anticorps
  • C630028C02Rik anticorps
  • DAB1 anticorps
  • disabled-1 anticorps
  • LOC100232823 anticorps
  • scm anticorps
  • scr anticorps
  • scrambler anticorps
  • si:dkey-242m13.1 anticorps
  • yot anticorps
  • zgc:136547 anticorps

Protein level used designations for DAB1

disabled homolog 1 , yotari , disabled1 , disabled homolog 1 (Drosophila) , DAB1 variant protein-like , disabled homolog 1-like , disabled 1 type B , disabled homolog 1b

GENE ID SPECIES
1600 Homo sapiens
13131 Mus musculus
266729 Rattus norvegicus
374083 Gallus gallus
100037307 Sus scrofa
100232823 Taeniopygia guttata
538818 Bos taurus
610344 Canis lupus familiaris
692351 Danio rerio
740508 Pan troglodytes
100337993 Oryctolagus cuniculus
100453388 Pongo abelii
100583389 Nomascus leucogenys
100049825 Equus caballus
100729327 Cavia porcellus
678641 Danio rerio
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