DnaJ (Hsp40) Homolog, Subfamily C, Member 6 Protéines (DNAJC6)

DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. De plus, nous expédions DNAJC6 Anticorps (38) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
DNAJC6 9829 O75061
DNAJC6 72685 Q80TZ3
Rat DNAJC6 DNAJC6 313409  
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Showing 3 out of 4 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails

DNAJC6 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour DnaJ (Hsp40) Homolog, Subfamily C, Member 6 (DNAJC6) partenaires d'interaction

Human DnaJ (Hsp40) Homolog, Subfamily C, Member 6 (DNAJC6) interaction partners

  1. DNAJC6 mutations are not common causes of early onset Parkinson's disease in Chinese population

  2. DNAJC6 mutations are associated with early-onset Parkinson's disease.

  3. DNAJC6 is up-regulated in hepatocellular carcinoma tissues and up-regulation of DNAJC6 expression predicts poor outcome in patients with HCC (Montrer FAM126A Protéines)

  4. Missense mutations in DNAJC6 does not play a major role in PD in the Chinese population.

  5. we did not detect any heterozygous or homozygous c.801-2A>G mutation in DNAJC6 in a cohort of Parkinson disease patients from southern Spain.

  6. This review presented that DNAJC6 in recessive forms of juvenile parkinsonism.

  7. Our findings further establish DNAJC6 as a juvenile parkinsonism gene, and expand the spectrums of the parkinsonism phenotype and DNAJC6 mutation

  8. study reports a homozygous mutation in DNAJC6 in two patients with autosomal-recessive juvenile Parkinsonism; the mutation was associated with abnormal transcripts and marked reduced DNAJC6 mRNA level

  9. The DNAJC6 gene encodes auxilin-1, a protein required for clathrin-dependent recycling of synaptic vesicles in neurons that is possibly at the origin of the mental retardation and epilepsy phenotype

  10. there are two auxilins with overlapping functions; they not only facilitate the uncoating of clathrin-coated vesicles but also prevent the formation of nonproductive clathrin cages in the cytosol

Cow (Bovine) DnaJ (Hsp40) Homolog, Subfamily C, Member 6 (DNAJC6) interaction partners

  1. Data suggest that anionic lipids (such as phosphatidylinositol phosphates) play crucial role in localization of peripheral membrane proteins (such as auxilin-1, PTEN [phosphatase and tensin homolog], and talin-1 (Montrer TLN1 Protéines)). [review-like article]

  2. Structure of clathrin coat with bound Hsc70 (Montrer HSPA8 Protéines) and auxilin.

  3. Auxilin binding produces a local change in heavy-chain contacts, creating a detectable global distortion of the clathrin coat [auxilin]

  4. timing of auxilin recruitment determines the onset of uncoating

  5. Results describe the recruitment dynamics of GAK and auxilin to clathrin-coated pits during endocytosis.

  6. Coats assembled from recombinant clathrin are good substrates for ATP- and auxilin-dependent, Hsc70 (Montrer HSPA8 Protéines)-catalyzed uncoating.

Profil protéine DNAJC6

Profil protéine

DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000

Gene names and symbols associated with DNAJC6

  • DnaJ heat shock protein family (Hsp40) member C6 (DNAJC6)
  • DnaJ heat shock protein family (Hsp40) member C6 (Dnajc6)
  • 2810027M23Rik Protéine
  • DJC6 Protéine
  • mKIAA0473 Protéine

Protein level used designations for DNAJC6

DnaJ (Hsp40) homolog, subfamily B, member 6 , auxilin , dnaJ homolog subfamily C member 6 , putative tyrosine-protein phosphatase auxilin

GENE ID SPECIES
9829 Homo sapiens
489553 Canis lupus familiaris
406190 Sus scrofa
317659 Bos taurus
72685 Mus musculus
313409 Rattus norvegicus
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