anti-Double Homeobox 4 (DUX4) Anticorps

DUX4 is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. De plus, nous expédions et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DUX4 100288687 Q9UBX2;
DUX4    
DUX4    
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Top anti-Double Homeobox 4 Anticorps sur anticorps-enligne.fr

Showing 10 out of 173 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Chien Lapin Inconjugué WB Host: Rabbit Target Name: DUX1 Sample Tissue: Human HCT15 Whole Cell  Antibody Dilution: 1ug/ml 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB Host: Rabbit Target Name: DUX4 Sample Type: Ovary tumor lysates Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué ICC, IF, IHC, WB Dux4 Western Blotting on C2C12 cells 1 in 1000 copy. 100 μg 3 to 4 Days
$453.70
Détails
Humain Lapin Inconjugué WB Host:  Rabbit  Target Name:  DUX4  Sample Type:  THP-1 Whole cell lysates  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$289.00
Détails
Humain Souris FITC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Tissue: C2C12 myoblast cells. Species: Mouse. Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain. Western Blot analysis of Mouse C2C12 cell lysate showing detection of DUX4 protein using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Cells transfected with pCS2+DUX4 which, contains an additional upstream start site. 100 μg 3 to 4 Days
$504.40
Détails
Humain Souris APC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Tissue: C2C12 myoblast cells. Species: Mouse. Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain. Western Blot analysis of Mouse C2C12 cell lysate showing detection of DUX4 protein using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Cells transfected with pCS2+DUX4 which, contains an additional upstream start site. 100 μg 3 to 4 Days
$513.50
Détails
Humain Souris PerCP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Tissue: C2C12 myoblast cells. Species: Mouse. Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain. Western Blot analysis of Mouse C2C12 cell lysate showing detection of DUX4 protein using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Cells transfected with pCS2+DUX4 which, contains an additional upstream start site. 100 μg 3 to 4 Days
$513.50
Détails
Humain Souris Atto 488 ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Tissue: C2C12 myoblast cells. Species: Mouse. Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain. Western Blot analysis of Mouse C2C12 cell lysate showing detection of DUX4 protein using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Cells transfected with pCS2+DUX4 which, contains an additional upstream start site. 100 μg 3 to 4 Days
$514.80
Détails
Humain Souris Atto 594 ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Tissue: C2C12 myoblast cells. Species: Mouse. Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain. Western Blot analysis of Mouse C2C12 cell lysate showing detection of DUX4 protein using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Cells transfected with pCS2+DUX4 which, contains an additional upstream start site. 100 μg 3 to 4 Days
$514.80
Détails
Humain Souris Atto 565 ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Tissue: C2C12 myoblast cells. Species: Mouse. Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain. Western Blot analysis of Mouse C2C12 cell lysate showing detection of DUX4 protein using Mouse Anti-DUX4 Monoclonal Antibody, Clone P2B1 . Primary Antibody: Mouse Anti-DUX4 Monoclonal Antibody  at 1:1000. Cells transfected with pCS2+DUX4 which, contains an additional upstream start site. 100 μg 3 to 4 Days
$514.80
Détails

anti-Double Homeobox 4 Anticorps mieux référencés

  1. Human Monoclonal DUX4 Primary Antibody pour ICC, IF - ABIN4306428 : Snider, Geng, Lemmers, Kyba, Ware, Nelson, Tawil, Filippova, van der Maarel, Tapscott, Miller: Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene. dans PLoS genetics 2010 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre Double Homeobox 4 partenaires d’interaction

Human Double Homeobox 4 (DUX4) interaction partners

  1. Homeotic DUX4 Genes that Control Human Embryonic Development at the Two-Cell Stage Are Surrounded by Regions Contacting with rDNA Gene Clusters

  2. IGH-DUX4 translocation occurs on the silenced IGH allele in B-cell acute lymphoblastic leukemia.

  3. Authors examined the correlation between MRI characteristics, muscle pathology and expression of DUX4 target genes. Results show that the presence of elevated MRI short tau inversion recovery signal has substantial predictive value in identifying muscles with active disease as determined by histopathology and DUX4 target gene expression.

  4. These and other approaches identified the Nucleosome Remodeling Deacetylase (NuRD) and Chromatin Assembly Factor 1 (CAF-1) complexes as necessary for DUX4 repression in human skeletal muscle cells and induced pluripotent stem (iPS) cells.Furthermore, DUX4-induced expression of MBD3L proteins partly relieved this repression in FSHD muscle cells.

  5. Expression of DUX4-fl is regulated by multiple epigenetic pathways.

  6. cis duplications of D4Z4 repeats explain DUX4 expression and disease presentation in FSHD2 families with unusual long D4Z4 repeats on 4qA chromosomes.

  7. The study revealed the basis for target DNA recognition by DUX4.

  8. We generated FSHD2-derived isogenic control clones with SMCHD1 mutation corrected by clustered regularly interspaced short palindromic repeats (CRISPR)/ CRISPR associated 9 (Cas9) and homologous recombination and found in the myocytes obtained from these clones that DUX4 basal expression and the OS-induced upregulation were markedly suppressed due to an increase in the heterochromatic state at 4q35.

  9. Cyclic AMP production reduces DUX4 expression through a protein kinase A-dependent mode of action in facioscapulohumeral muscular dystrophy patient myotubes.

  10. Sporadic DUX4 expression seen in FSHD myocytes is due to the incomplete repression by the PRC2 complex.

  11. Biallelic DUX4 expression lowers the threshold for disease presentation and is a modifier for disease severity in FSHD2.

  12. recurrent IGH-DUX4 or ERG-DUX4 fusions, ETV6-RUNX1-like gene-expression profile in B-cell precursor acute lymphoblastic leukaemia, is reported.

  13. The recent identification of aberrant activation of DUX4 transcription in Facioscapulohumeral muscular dystrophy.

  14. Case Report: t(10;19) CIC-DUX4 undifferentiated small round cell sarcoma of the abdominal wall.

  15. The DUX4 homeodomains mediate inhibition of myogenesis and are functionally exchangeable with the Pax7 homeodomain.

  16. selective loss of H3K9me3 from the DUX4 locus is associated with expression of DUX4 in late-phase squamous differentiation of human keratinocytes in vitro and in vivo.

  17. We discuss the involvement of this rearrangement in Facioscapulohumeral dystrophy (FSHD), since all mutations in SMCHD1 are not associated with D4Z4 hypomethylation and do not always segregate with the disease

  18. The study describes a model system for inducible DUX4 expression that enables reproducible and synchronized experiments and validates the fidelity and facioscapulohumeral dystrophy (FSHD) relevance of multiple distinct models of DUX4 expression.

  19. DUX4 and Dux may regulate some common pathways, and despite diverging from a common progenitor under different selective pressures for millions of years, the two genes maintain partial functional homology.

  20. We propose that DUX4 controls the cellular migration of mesenchymal stem cells through the CXCR4 receptor.

Double Homeobox 4 (DUX4) profil antigène

Profil protéine

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Double Homeobox 4 (DUX4) Anticorps

  • double homeobox, 4 (DUX4) anticorps
  • double homeobox 4 (DUX4) anticorps
  • DUX4 anticorps
  • DUX4L anticorps

Protein level used designations for anti-Double Homeobox 4 (DUX4) Anticorps

double homeobox, 4 , Double homeobox protein 10 , double homeobox 4-like , double homeobox protein 10 , double homeobox protein 4 , double homeobox protein 4/10

GENE ID SPECIES
471420 Pan troglodytes
750468 Pan troglodytes
100288687 Homo sapiens
Fournisseurs de qualité sélectionnés pour anti-Double Homeobox 4 (DUX4) Anticorps
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