anti-Dual Specificity Phosphatase 1 (DUSP1) Anticorps

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. De plus, nous expédions DUSP1 Kits (30) et DUSP1 Protéines (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DUSP1 1843 P28562
DUSP1 114856 Q64623
DUSP1 19252 P28563
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Top anti-DUSP1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 131 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, IHC ABIN184638 (3.8µg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. ABIN184638 (0.3µg/ml) staining of HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$358.02
Détails
Poulet Lapin Inconjugué IHC, WB Immunohistochemical analysis of DUSP1 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of DUSP1 expression in HeLa (A) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using MKP1 (Phospho-Ser359) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using MKP1 (Ab-359) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MKP1 (Ab-359) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Boeuf (Vache) Chèvre Inconjugué IHC (p), WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$462.00
Détails
Humain Chèvre Inconjugué IHC (p), IHC, ELISA, WB ABIN257653 staining (2µg/ml) of HeLa lysate (RIPA buffer, 35µg total protein per lane). Western Blot: MKP-1/DUSP1 Antibody [ABIN257653] - (0.3ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$485.88
Détails
Roussette (Chauve-souris) Chèvre Inconjugué ELISA, IHC, IHC (p), WB Human Prostate (formalin-fixed, paraffin-embedded) stained with DUSP1 antibody ABIN351458 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-DUSP1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Chien Lapin Inconjugué IHC, IHC (p), WB Human Placenta (formalin-fixed, paraffin-embedded) stained with DUSP1 antibody ABIN337195 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-DUSP1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$727.83
Détails
Humain Lapin Inconjugué IF, WB The anti-DUSP1 Pab (ABIN392905) is used in Western blot to detect DUSP1 in 293 cell lysate. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails

anti-DUSP1 Anticorps mieux référencés

  1. Human Polyclonal DUSP1 Primary Antibody pour IF (p), IHC (p) - ABIN735368 : Kato, Naiki-Ito, Naiki, Suzuki, Yamashita, Sato, Sagawa, Kato, Kuno, Takahashi: Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis. dans Oncotarget 2016 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal DUSP1 Primary Antibody pour IF (p) - ABIN894519 : Khadir, Tiss, Abubaker, Abufarha, Al-Khairi, Cherian, John, Kavalakatt, Warsame, Al-Madhoun, Al-Ghimlas, Elkum, Behbehani, Dermime, Dehbi: MAP kinase phosphatase DUSP1 is overexpressed in human obese and modulated by physical activity. dans American journal of physiology. Endocrinology and metabolism 2014 (PubMed)

  3. Human Monoclonal DUSP1 Primary Antibody pour IF, ELISA - ABIN515099 : Chao, Sun, Peng, Wu: Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells. dans International journal of molecular sciences 2016 (PubMed)

  4. Human Polyclonal DUSP1 Primary Antibody pour IHC (p), IHC - ABIN257653 : Alessi, Smythe, Keyse: The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts. dans Oncogene 1993 (PubMed)

Plus d’anticorps contre DUSP1 partenaires d’interaction

Human Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. SIN (Montrer EFS Anticorps) attenuated LPS (Montrer IRF6 Anticorps)-induced inflammatory injury by regulation of miR (Montrer MLXIP Anticorps)-101, MKP-1 and JNK (Montrer MAPK8 Anticorps) pathway.

  2. miR (Montrer MLXIP Anticorps)-202-3p is upregulated in type 1 gastric neuroendocrine neoplasms (g-NENs) lesions and might play important roles in the pathogenesis of type 1 g-NENs by targeting DUSP1.

  3. Downregulation of the expression of DUSP1 or protein phosphatase 1 led to a decline in the beta2adrenergic receptormediated dephosphorylation of ERK1/2.

  4. the expression of DUSP1 was lower in OA FLSs than in normal FLSs, and DUSP1 may inhibit the expression of OA-associated mediators, MMP-13 (Montrer MMP13 Anticorps) and COX-2 (Montrer COX2 Anticorps), by suppressing the activation of p38 MAPK (Montrer MAPK14 Anticorps) and JNK (Montrer MAPK8 Anticorps) pathways in OA FLSs.

  5. Curcumin suppressed CXCL5 (Montrer CXCL5 Anticorps) expression by direct inhibition of IKKbeta (Montrer IKBKB Anticorps) phosphorylation, and inhibition of p38 MAPK (Montrer MAPK14 Anticorps) via induction of negative regulator MKP-1.

  6. MKP-1 is a redox-regulated master controller of monocyte function and macrophage phenotype. (Review)

  7. We propose a signaling cascade involving ARID1A (Montrer ARID1A Anticorps), GADD45B (Montrer GADD45B Anticorps) and DUSP1 as mediators of the romidepsin effects in GCC (Montrer GUCY2C Anticorps) cells.

  8. this work indicates that suppression of JNK1 (Montrer MAPK8 Anticorps)/2 activity by MKP-1 maintains PARP-1 (Montrer PARP1 Anticorps) levels and suggests that MKP-1-mediated cisplatin resistance can be bypassed by PARP-1 (Montrer PARP1 Anticorps) inhibition.

  9. Mean morning and evening DUSP1 mRNA levels showed significant increase during Ramadan compared to Shabaan, however, its diurnal rhythm was maintained. Morning IL-1alpha mRNA expression remained significantly higher than in the evening during Ramadan, but was markedly decreased compared to Shabaan.

  10. Methylation-mediated silencing of the DUSP-1 promoter does not appear to be associated with reduced expression, indicating the involvement of other factors in specific suppression of DUSP-1 in diabetes-associated cardiac hypertrophy.

Cow (Bovine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. MKP-1 is the specific phosphatase induced by AngII and involved in the negative feedback mechanism ensuring adequate ERK1/2-mediated aldosterone production in response to the hormone.

Mouse (Murine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. Low DUSP1 expression is associated with cerebral ischaemia reperfusion injury.

  2. Results indicate that the upregulation of anterior cingulate cortex (ACC, areas 24a and 24b) MKP-1 is necessary for the expression of depressive symptoms induced by chronic pain, chronic stress, and optogenetic activation of the ACC.

  3. The results suggested that DUSP1 gene silencing promoted the release of proinflammatory cytokines through activation of the MAPK (Montrer MAPK1 Anticorps) signaling pathway in mice with acute pancreatitis.

  4. The cardiac ischemia/reperfusion injury - induced DUSP1 deficiency promoted the activation of JNK (Montrer MAPK8 Anticorps) which upregulated the expression of the mitochondrial fission factor (Mff (Montrer MFF Anticorps)).

  5. Study demonstrates that MKP-1 serves as a master-regulator of macrophage phenotype and function and its dysregulation by metabolic stress may be a major contributor to atherogenesis and the progression of atherosclerotic plaques.

  6. FAM3D inhibits glucagon secretion via MKP1-dependent suppression of ERK1/2 signaling.

  7. these data show that MKP-1 is an important endogenous suppressor of innate immune responses involved in the regulation of blood-testis barrier barrier dynamic

  8. MKP-1 regulates IL-1beta (Montrer IL1B Anticorps) production through stabilization of HIF-1alpha (Montrer HIF1A Anticorps). The induction of HIF-1alpha (Montrer HIF1A Anticorps) protein in MKP-1 deficiency is partly due to p38MAPK (Montrer MAPK14 Anticorps) activation in response to LPS (Montrer TLR4 Anticorps).

  9. this work identifies a previously unrecognized role for DUSP1 in regulating autophagy.

  10. c-FOS and DUSP1 expression levels determine the threshold of tyrosine kinase (Montrer TYRO3 Anticorps) inhibitor (TKI) efficacy, such that growth-factor-induced expression of c-FOS and DUSP1 confers intrinsic resistance to TKI therapy in a wide-ranging set of leukemias.

Pig (Porcine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. Agonist stimulation of vascular smooth muscle increases PKC (Montrer FYN Anticorps) activity, which, in turn, increases MKP-1 activity and maintains MAPK1 (Montrer MAPK1 Anticorps) activity at submaximal values.

DUSP1 profil antigène

Profil protéine

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.

Gene names and symbols associated with DUSP1

  • dual specificity phosphatase 1 (DUSP1) anticorps
  • dual specificity phosphatase 1 (Dusp1) anticorps
  • dual specificity phosphatase 1 (dusp1) anticorps
  • dual specificity phosphatase 1 S homeolog (dusp1.S) anticorps
  • 3CH134 anticorps
  • cb269 anticorps
  • CL100 anticorps
  • DUSP1 anticorps
  • erp anticorps
  • HVH1 anticorps
  • id:ibd2586 anticorps
  • mkp-1 anticorps
  • Mkp1 anticorps
  • PTPN10 anticorps
  • Ptpn16 anticorps
  • sb:cb269 anticorps
  • U19515 anticorps
  • wu:fd19g02 anticorps
  • wu:fe50g09 anticorps
  • XCL100 anticorps
  • zgc:55920 anticorps

Protein level used designations for DUSP1

MAP kinase phosphatase 1 , dual specificity protein phosphatase 1 , dual specificity protein phosphatase hVH1 , mitogen-activated protein kinase phosphatase 1 , protein-tyrosine phosphatase CL100 , serine/threonine specific protein phosphatase , 3CH134/CL100 PTPase , MAP kinase phosphatase-1 , mitogen-activated protein (MAP) kinase phosphatase-1 , oxidative stress-inducible protein tyrosine phosphatase , protein tyrosine phosphatase non-receptor type 16 , protein tyrosine phosphatase, non-receptor type 16 , protein-tyrosine phosphatase non-receptor type 16 , dual specificity phosphatase 1 , mitogen-activated protein kinase phosphatase-1 , protein-tyrosine phosphatase 3CH134 , protein-tyrosine phosphatase ERP , mkp-1 , MAPK phosphatase 1 , LOW QUALITY PROTEIN: dual specificity protein phosphatase 1 , MAP kinase phosphatase XCL100(beta) protein , XCL100-beta , dual specificity protein phosphatase 1-B , dusp1-b

GENE ID SPECIES
1843 Homo sapiens
114856 Rattus norvegicus
374192 Gallus gallus
471742 Pan troglodytes
539175 Bos taurus
100219518 Taeniopygia guttata
100340993 Oryctolagus cuniculus
19252 Mus musculus
406340 Danio rerio
100522469 Sus scrofa
489117 Canis lupus familiaris
100725668 Cavia porcellus
398254 Xenopus laevis
101107632 Ovis aries musimon
Fournisseurs de qualité sélectionnés pour anti-DUSP1 (DUSP1) Anticorps
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