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Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995 [PubMed 7738094]). De plus, nous expédions Dynein, Cytoplasmic 1, Light Intermediate Chain 2 Protéines (7) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal DYNC1LI2 Primary Antibody pour IP, WB - ABIN947797
Malik, Saito, Takaoka, Miki, Nakanishi: BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein. dans Cell cycle (Georgetown, Tex.) 2016
Results suggest that dynein 2 light intermediate chain (D2LIC (Montrer DYNC2LI1 Anticorps)) is a bona fide subunit of cytoplasmic dynein (Montrer DYNC1H1 Anticorps) 2 that may play a role in maintaining Golgi organization by binding cytoplasmic dynein (Montrer DYNC1H1 Anticorps) 2 to its Golgi-associated cargo.
Results suggest that Par3 acts as a cortical factor that tethers microtubules through its association with LIC2 dynein.
Cortically localized dynein, essential for maintaining correct spindle orientation, consists majorly of LIC2-dynein, which interacts with cortical 14-3-3 epsilon (Montrer YWHAE Anticorps)- zeta and Par3 (Montrer F2RL2 Anticorps), conserved proteins required for orienting the spindle.
This study uncovers a novel functional hierarchy during mitotic checkpoint (Montrer BUB3 Anticorps) inactivation between the closely related but homologous LIC subunits of cytoplasmic dynein (Montrer DYNC1H1 Anticorps).
These results suggest that cytoplasmic dynein (Montrer DYNC1H1 Anticorps) 1 binds to BRCA2 (Montrer BRCA2 Anticorps) through the latter's centrosomal localization signal and BRCA2 (Montrer BRCA2 Anticorps) mediates the cohesion between centrosomes during the S phase, potentially serving as a cell-cycle checkpoint.
although dynein lacking light intermediate chains (LICs) drives microtubule gliding at normal rates, the LICs are required for the formation and maintenance of a bipolar spindle.
using a variety of complementary approaches, our results indicate a novel specific role for the LICs in dynein recruitment to components of the late endocytic pathway.
FIP3 (Montrer IKBKG Anticorps) was identified as the first membrane-associated interacting-partner for DLIC-2.
Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995
cytoplasmic dynein 1 light intermediate chain 2
, dynein, cytoplasmic 1, light intermediate chain 2
, LIC-2 dynein light intermediate chain 53/55
, dynein light intermediate chain 2, cytosolic
, dynein, cytoplasmic, light intermediate polypeptide 2
, dynein, cytoplasmic, light intermediate chain 2