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Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995 [PubMed 7738094]). De plus, nous expédions Dynein, Cytoplasmic 1, Light Intermediate Chain 2 Anticorps (34) et et beaucoup plus de produits pour cette protéine.
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Results suggest that dynein 2 light intermediate chain (D2LIC (Montrer DYNC2LI1 Protéines)) is a bona fide subunit of cytoplasmic dynein (Montrer DYNC1H1 Protéines) 2 that may play a role in maintaining Golgi organization by binding cytoplasmic dynein (Montrer DYNC1H1 Protéines) 2 to its Golgi-associated cargo.
Results suggest that Par3 acts as a cortical factor that tethers microtubules through its association with LIC2 dynein.
Cortically localized dynein, essential for maintaining correct spindle orientation, consists majorly of LIC2-dynein, which interacts with cortical 14-3-3 epsilon (Montrer YWHAE Protéines)- zeta and Par3 (Montrer F2RL2 Protéines), conserved proteins required for orienting the spindle.
This study uncovers a novel functional hierarchy during mitotic checkpoint (Montrer BUB3 Protéines) inactivation between the closely related but homologous LIC subunits of cytoplasmic dynein (Montrer DYNC1H1 Protéines).
These results suggest that cytoplasmic dynein (Montrer DYNC1H1 Protéines) 1 binds to BRCA2 (Montrer BRCA2 Protéines) through the latter's centrosomal localization signal and BRCA2 (Montrer BRCA2 Protéines) mediates the cohesion between centrosomes during the S phase, potentially serving as a cell-cycle checkpoint.
although dynein lacking light intermediate chains (LICs) drives microtubule gliding at normal rates, the LICs are required for the formation and maintenance of a bipolar spindle.
using a variety of complementary approaches, our results indicate a novel specific role for the LICs in dynein recruitment to components of the late endocytic pathway.
FIP3 (Montrer IKBKG Protéines) was identified as the first membrane-associated interacting-partner for DLIC-2.
Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995
cytoplasmic dynein 1 light intermediate chain 2
, dynein, cytoplasmic 1, light intermediate chain 2
, LIC-2 dynein light intermediate chain 53/55
, dynein light intermediate chain 2, cytosolic
, dynein, cytoplasmic, light intermediate polypeptide 2
, dynein, cytoplasmic, light intermediate chain 2