EGF-Like-Domain, Multiple 7 (EGFL7) Kits ELISA

EGFL7 encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. De plus, nous expédions EGFL7 Anticorps (75) et EGFL7 Protéines (13) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
EGFL7 353156 Q9QXT5
EGFL7 51162 Q9UHF1
EGFL7 245963 Q6AZ60
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Top EGFL7 Kits ELISA sur

Showing 4 out of 21 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 13.1 pg/mL 31.25 pg/mL - 2000 pg/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
Souris 0.062 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
Rat 1.56 ng/mL n/a   96 Tests Connectez-vous pour afficher 15 to 18 Days
Humain 14.8 pg/mL 31.2 pg/mL - 2000 pg/mL   96 Tests Connectez-vous pour afficher 15 to 17 Days

EGFL7 Kits ELISA mieux référencés

  1. Human EGFL7 Kit ELISA pour Sandwich ELISA - ABIN1874436 : Hansen, Andersen, Olsen, Sørensen, Jakobsen: Prognostic importance of circulating epidermal growth factor-like domain 7 in patients with metastatic colorectal cancer treated with chemotherapy and bevacizumab. dans Scientific reports 2017 (PubMed)

Plus Kits ELISA pour EGFL7 partenaires d'interaction

Xenopus laevis EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. we demonstrate for the first time the mechanisms by which lumens are generated within the major vessels in Xenopus and implicate EGFL7 in modulating cell shape and cell-cell junctions to drive proper lumen morphogenesis.

  2. CASZ1/Egfl7/RhoA (Montrer RHOA Kits ELISA) pathway is necessary for promoting endothelial cell behaviors associated with proper vascular assembly.

Zebrafish EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. Under up-regulation of TIE2 (Montrer TEK Kits ELISA)-R849W, egfl7 could be considered a potential reason for venous defects. Moreover, the wnt (Montrer WNT2 Kits ELISA) pathway may perform an important role as a key trigger for head multi-malformations.

  2. These data suggest that Egfl7 provides endothelial cells (EC) with a cue for their extension into the vascular area and in establishing EC cell polarity.

  3. EGFL7 provides a proper microenvironment for endothelial cell migration, thereby enabling accurate patterning.

Mouse (Murine) EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. EGFL7 reduces CNS inflammation in the experimental autoimmune encephalomyelitis mouse model of multiple sclerosis.

  2. Egfl7 is crucial for placental vascularization and embryonic growth.

  3. the angiogenic factor (Montrer VEGFA Kits ELISA) Egfl7 activates the Flt3/Flt3 (Montrer FLT3 Kits ELISA) ligand (Montrer FLT3LG Kits ELISA) pathway and is a key molecular driver enforcing thymus progenitor generation and thereby directly links endothelial cell biology to the production of T cell-based adaptive immunity

  4. EGFL7 is required for VEGF (Montrer VEGFA Kits ELISA) upregulation of the Akt (Montrer AKT1 Kits ELISA)/Erk (1 (Montrer MAPK3 Kits ELISA)/2) pathway during angiogenesis.

  5. EGFL7 enhances EGFR (Montrer EGFR Kits ELISA)-AKT (Montrer AKT1 Kits ELISA) signaling, epithelial-mesenchymal transition, and metastasis of gastric cancer cells.

  6. Egfl7 could be a HIF-1alpha (Montrer HIF1A Kits ELISA) responsive gene regulated by oxygen tension.

  7. Using the BPH (Montrer GLI3 Kits ELISA)/5 model of pre-eclampsia (PE), we show that the downregulation of Egfl7 in compromised placentas occurs prior to the onset of characteristic maternal signs of PE.

  8. egfl7 is initially expressed in all endothelial cells and then is progressively restricted to veins and to their neighbouring capillaries.

  9. EGFL7 is expressed in the bone microenvironment and has a role in promoting endothelial cell migration and tube-like structure formation through integrin-mediated pathways.

  10. Expression of Egfl7 in breast and lung carcinoma cells accelerates tumor growth and metastasis in immunocompetent mice but not in immunodeficient mice.

Human EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. EGFL7 was found to be a potential predictor for HCC survival and metastasis state.

  2. Levels of both EGFL7 mRNA and EGFL7 protein are increased in blasts of patients with acute myeloid leukemia (Montrer BCL11A Kits ELISA) (AML (Montrer RUNX1 Kits ELISA)) compared with normal bone marrow cells. High EGFL7 mRNA expression associates with lower complete remission rates, and shorter event-free and overall survival in older (age >/=60 y) and younger (age <60 y) patients with cytogenetically normal AML (Montrer RUNX1 Kits ELISA).

  3. In conclusion, miR (Montrer MLXIP Kits ELISA)-126 could inhibit tumor proliferation and angiogenesis of hepatocellular carcinoma by down-regulating EGFL7 expression

  4. This phase II trial evaluated the efficacy of parsatuzumab (also known as MEGF0444A), a humanized anti-EGFL7 IgG1 monoclonal antibody, in combination with modified FOLFOX6 (mFOLFOX6) (folinic acid, 5-fluorouracil, and oxaliplatin) bevacizumab in patients with previously untreated metastatic colorectal cancer

  5. Oncogenic activation of EGFRwt in GBM is likely maintained by a continuous EGFL7 autocrine flow line.

  6. our results indicated epidermal growth factor-like domain multiple 7 protein participates in growth hormone-secreting pituitary adenoma proliferation and invasion regulation via Notch2/DLL3 signaling pathway. These findings raised the possibility that epidermal growth factor-like domain multiple 7 protein might serve as a useful biomarker to assess growth hormone-secreting pituitary adenoma invasion and prognosis

  7. Egfl7 is thus an endogenous and constitutive repressor of blood vessel endothelial cell activation in normal and inflammatory conditions and participates in a loop of regulation of activation of these cells by pro-inflammatory cytokines.

  8. Up-regulated MALAT1 promoted the invasion and metastasis of GC, and the increase of EGFL7 expression was a potential mechanism via altering its H3 histone (Montrer HIST1H3B Kits ELISA) acetylation level

  9. These findings suggest that the stimulating effect of EGFL7-ESCs on fibroblast proliferation and migration may provide a useful strategy for wound healing.

  10. A gene expression study was conducted to investigate the levels of Egfl7 and miRNA126-5p in human carotid artery atherosclerotic plaques

EGFL7 profil antigène

Antigen Summary

This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with EGFL7

  • EGF like domain multiple 7 S homeolog (egfl7.S) anticorps
  • EGF like domain multiple 7 (EGFL7) anticorps
  • EGF-like-domain, multiple 7 (egfl7) anticorps
  • EGF like domain multiple 7 (egfl7) anticorps
  • EGF-like domain 7 (Egfl7) anticorps
  • EGF-like-domain, multiple 7 (Egfl7) anticorps
  • EGFL7 anticorps
  • MGC53105 anticorps
  • MGC147423 anticorps
  • NEU1 anticorps
  • RP11-251M1.2 anticorps
  • VE-STATIN anticorps
  • xegfl7 anticorps
  • zgc:136669 anticorps
  • zgc:152804 anticorps
  • ZNEU1 anticorps

Protein level used designations for EGFL7

EGF-like-domain, multiple 7 , epidermal growth factor-like protein 7 , rp11-251m1.2 , EGF-like protein 7 , NEU1 protein , NOTCH4-like protein , multiple EGF-like domains protein 7 , multiple epidermal growth factor-like domains protein 7 , vascular endothelial statin , vascular endothelial-statin , EGF-like domain 7 , EGF-like domain-containing protein 7 , Estrogen-regulated protein CBL20 20.4kD , Estrogen-regulated protein CBL20, 20.4kD , multiple EGF-like domain protein 7 , multiple epidermal growth factor-like domain protein 7

379835 Xenopus laevis
417137 Gallus gallus
464868 Pan troglodytes
491250 Canis lupus familiaris
613671 Bos taurus
678640 Danio rerio
780371 Xenopus (Silurana) tropicalis
100226311 Taeniopygia guttata
353156 Mus musculus
51162 Homo sapiens
245963 Rattus norvegicus
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