Echinoderm Microtubule Associated Protein Like 4 Protéines (EML4)

May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity). De plus, nous expédions EML4 Anticorps (38) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Rat EML4 EML4 313861  
EML4 27436 Q9HC35
EML4 78798 Q3UMY5
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Top EML4 Protéines sur anticorps-enligne.fr

Showing 4 out of 4 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 2 to 3 Days
$814.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails

EML4 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Plus protéines pour Echinoderm Microtubule Associated Protein Like 4 (EML4) partenaires d'interaction

Human Echinoderm Microtubule Associated Protein Like 4 (EML4) interaction partners

  1. Mutation testing at diagnosis is feasible in the vast majority of patients with Stage IV adenocarcinoma of the lung. Patients with EGFR (Montrer EGFR Protéines) or EML4ALK mutation and those who received pemetrexed maintenance had better clinical outcomes.

  2. Our analysis indicated that ALK-EML4 positive non-small-cell lung cancers comprised a unique subgroup of adenocarcinomas with distinct clinicopathological characteristics. Incidence of ALK positivity was found to be higher in females and never smokers.

  3. Coupling an EML4-ALK-centric interactome with RNA interference identifies sensitizers to ALK inhibitors

  4. identified EML4-ALK gene rearrangement in expanded circulating tumor cells from a patient with ALK-positive lung adenocarcinoma

  5. Knockdown of SMYD2 as well as treatment with a SMYD2 inhibitor in two NSCLC cell lines with an EML4-ALK gene significantly attenuated the phosphorylation levels of the EML4-ALK protein.

  6. The EML4-ALK-mediated upregulation of HIF1alpha, HK2 and glycolytic metabolism was also highly active in vivo as demonstrated by fluorodeoxyglucose-positron emission tomography imaging of xenografts grown from EML4-ALK-positive NSCLC cells.

  7. We assessed the prevalence of EML4-ALK rearrangement gene measured by immunohistochemistry in an unselected population-based consecutive cohort of patients with adenocarcinoma of the lung (ACL (Montrer ACLY Protéines)), and the correlation with smoking history, thyroid transcription factor 1 (TTF1 (Montrer NKX2-1 Protéines)), gender and age

  8. Our findings show that group EML4-ALK variants 3a/b in non-small cell lung cancer may be a major source of ALK inhibitor resistance in the clinic.

  9. EML4-ALK rearrangement detection in malignant pleural effusions is a complementary method for EML4-ALK detection. VETANA and qRT-PCR are more appropriate for MPE detection. EML4-ALK rearrangement in pleural effusions has a predictive value for treatment.

  10. EML4-ALK-positive lung cancer is often highly progressive.

Profil protéine EML4

Profil protéine

May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).

Gene names and symbols associated with EML4

  • echinoderm microtubule associated protein like 4 (Eml4)
  • echinoderm microtubule associated protein like 4 (EML4)
  • echinoderm microtubule associated protein like 4 (eml4)
  • echinoderm microtubule associated protein like 4 S homeolog (eml4.S)
  • 4930443C24Rik Protéine
  • AI644019 Protéine
  • C2orf2 Protéine
  • ELP120 Protéine
  • EMAP-4 Protéine
  • EMAPL4 Protéine
  • EML4 Protéine
  • MGC89332 Protéine
  • ROPP120 Protéine

Protein level used designations for EML4

echinoderm microtubule-associated protein-like 4 , echinoderm microtubule associated protein like 4 , echinoderm microtubule-associated protein-like 4-like , restrictedly overexpressed proliferation-associated protein , ropp 120 , EMAP-4

GENE ID SPECIES
313861 Rattus norvegicus
483048 Canis lupus familiaris
540187 Bos taurus
100515021 Sus scrofa
448764 Xenopus (Silurana) tropicalis
459180 Pan troglodytes
715091 Macaca mulatta
771345 Gallus gallus
100053784 Equus caballus
100453034 Pongo abelii
27436 Homo sapiens
78798 Mus musculus
735022 Xenopus laevis
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