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ENC1 encodes a member of the kelch-related family of actin-binding proteins. De plus, nous expédions Ectodermal-Neural Cortex 1 (With BTB-Like Domain) Anticorps (62) et Ectodermal-Neural Cortex 1 (With BTB-Like Domain) Kits (4) et beaucoup plus de produits pour cette protéine.
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ENC1 interacts with the phosphorylated p62 (Montrer GTF2H1 Protéines) to impair autophagic degradation of mutant huntingtin (Montrer HTT Protéines) protein aggregates.
we identified ENC1 and UNC5C (Montrer Unc5c Protéines) as genes with convergent genetic, epigenetic, and transcriptomic evidence supporting a potential role in the dissociation of cognition and neuropathology in an aging population.
results suggest that upregulation of ENC-1 contributes to the development of HCL and provides new information on the possible dysregulation of ENC-1 including expression of a novel antisense gene, ENC-1AS (Montrer HEXB Protéines)
NRP (Montrer NAP1L1 Protéines)/B enhances oxidative stress responses in breast cancer cells via the Nrf2 (Montrer GABPA Protéines) pathway, identifying a novel role of nuclear matrix protein(s) in oxidative stress responses.
NRP (Montrer NAP1L1 Protéines)/B mutations impair Nrf2 (Montrer GABPA Protéines)-dependent NQO1 (Montrer NQO1 Protéines) induction in primary brain tumors.
ENC1 functions as a negative regulator of Nrf2 (Montrer GABPA Protéines) through suppressing Nrf2 (Montrer GABPA Protéines) protein translation.
The results are the first to demonstrate a role for ENC1 in the control of osteoblast differentiation. Additionally, the contrasting mineralization phenotypes and transcriptional patterns seen with coordinate knockdown of both ENC1 isoforms vs selective knockdown of 67 kDa ENC1 suggest opposing roles for the isoforms in regulation of osteoblastic differentiation, through effects on Alpl (Montrer ALPL Protéines) expression and phosphate cellular
Pallial expression of Enc1 RNA in postnatal mouse telencephalon.
This gene encodes a member of the kelch-related family of actin-binding proteins. The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2, and expression of this gene may play a role in malignant transformation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
ectodermal-neural cortex (with BTB-like domain)
, ectoderm-neural cortex protein 1
, ectodermal-neural cortex 1 (with BTB-like domain)
, kelch-like 35
, kelch-like family member 37
, kelch-like protein 37
, nuclear matrix protein NRP/B
, nuclear restricted protein, BTB domain-like (brain)
, p53-induced gene 10 protein
, tumor protein p53 inducible protein 10
, ectoderm neural cortex related-3
, ectoderm-neural cortex protein 1-like
, nuclear restrict protein in brain