Ectonucleoside Triphosphate diphosphohydrolase 1 Protéines (ENTPD1)

Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. De plus, nous expédions Ectonucleoside Triphosphate diphosphohydrolase 1 Anticorps (234) et Ectonucleoside Triphosphate diphosphohydrolase 1 Kits (17) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
ENTPD1 953 P49961
ENTPD1 12495 P55772
ENTPD1 64519 P97687
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Top Ectonucleoside Triphosphate diphosphohydrolase 1 Protéines sur anticorps-enligne.fr

Showing 10 out of 17 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,626.01
Détails
Baculovirus infected Insect Cells Souris His tag 10 μg Connectez-vous pour afficher 20 to 21 Days
$250.80
Détails
Escherichia coli (E. coli) Souris His tag,T7 tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$682.00
Détails
Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$720.00
Détails
Baculovirus infected Insect Cells Humain His tag 10 μg Connectez-vous pour afficher 20 to 21 Days
$316.80
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 2 to 3 Days
$814.00
Détails
Escherichia coli (E. coli) Humain His tag,T7 tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$656.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Baculovirus infected Insect Cells Humain His tag   10 μg Connectez-vous pour afficher 15 to 16 Days
$687.50
Détails

ENTPD1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , , ,
, , , ,
Mouse (Murine) , , ,
, ,
Rat (Rattus)

Plus protéines pour Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) partenaires d'interaction

Zebrafish Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) interaction partners

  1. Extracellular ATP hydrolysis via NTPDase1 action inhibits synaptic transmission by pannexin 1 (Montrer PANX1 Protéines)-mediated increase in pH buffering of the synaptic cleft.

Human Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) interaction partners

  1. ur results demonstrate that CD39 is upregulated on conventional CD4 (Montrer CD4 Protéines)+ and CD8 (Montrer CD8A Protéines)+ T cells at sites of acute infection and inflammation, and that CD39 dampens responses to bacterial infection.

  2. this paper shows that simultaneous overexpression of human E5NT and ENTPD1 protects porcine endothelial cells against H2O2-induced oxidative stress and cytotoxicity in vitro

  3. The peripheral blood mononuclear cells (PBMC) from the transgenic pigs were more resistant to lysis by pooled complement-preserved normal human serum than that from wild type (WT) pig. Accordingly, GGTA1 (Montrer GGTA1 Protéines) mutated piglets expressing hCD39 will provide a new organ source for xenotransplantation research

  4. Phosphoantigens (pAgs) induced expression of the ecto-ATPase CD39, which, however, not only hydrolyzed ATP but also abrogated the gammadelta T cell receptor (TCR) agonistic activity of self and microbial pAgs.

  5. These studies showed that the G allele of rs3176891 marks a haplotype associated with increased clotting and platelet aggregation attributable to a promoter variant associated with increased transcription, expression, and activity of NTPDase1.

  6. Transgenic expression of human CD39 is associated with increased renal fibrosis after ischemia in mice.

  7. CD39 overexpression protects against cerebral ischemia in a transgenic mouse model.

  8. Ablation of CD73 minimally effects in vivo thrombosis, but increased CD39 expression on hematopoietic-derived cells, especially monocytes, attenuates in vivo arterial thrombosis.

  9. Data show that Th17(CD39+) cells are markedly diminished and fail to generate AMP (Montrer APRT Protéines)/adenosine, thereby limiting control of both target cell proliferation and IL-17 (Montrer IL17A Protéines) production in juvenile autoimmune liver disease (AILD).

  10. concluded that CD39 and CD73 are molecular targets for the development of drugs for ALF (Montrer GTF2A1L Protéines) patients care

Mouse (Murine) Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) interaction partners

  1. Furthermore, our results suggest a crucial role for the enzyme CD39 in limiting P2X7 receptor (Montrer P2RX7 Protéines) proinflammatory responses since CD39(-/-) septic mice exhibited higher levels of IL-1beta (Montrer IL1B Protéines) in the brain.

  2. CD39 expression in macrophages limits P2X7 (Montrer P2RX7 Protéines)-mediated pro-inflammatory responses, scavenging extracellular ATP and ultimately generating adenosine. CD39 genetic deletion exacerbates sepsis-induced experimental liver injury.

  3. complete deletion of Cd39 paradoxically attenuates development of atherosclerosis in hyperlipidemic mice

  4. Deletion of CD39 and CD73 or both caused an inhibition of the microglia ramified phenotype in the brain with a reduction in the length of processes, branching frequency and number of intersections with Sholl spheres. In vitro, unlike wild-type microglia, cd39-/- and cd73-/- microglial cells were less complex and did not respond to ATP with the transformation into a more ramified phenotype.

  5. CD39 expression by Th17 cells allows the depletion of ATP and is crucial for IL-10 (Montrer IL10 Protéines) production and survival during the resolution of intestinal inflammation.

  6. Cardiac-specific expression of CD39 reduces myocardial dysfunction and infarct size following ischemia-reperfusion injury

  7. Data indicate that adenosine and CGS21680 upregulate CD39 and CD73 via E2F-1 (Montrer E2F1 Protéines) and CREB (Montrer CREB1 Protéines).

  8. Acute cigarette smoke exposure induced CD39 upregulation in murine lungs and BALF cells. CD39 inhibition and deficiency led to augmented lung inflammation.

  9. T Lymphocyte Inhibition by Tumor-Infiltrating Dendritic Cells Involves Ectonucleotidase CD39 but Not Arginase-1 (Montrer ARG1 Protéines).

  10. CD39 role in neuroinflammation: CD39 defines regulatory phenotypes in CD4 (Montrer CD4 Protéines)-positive T cells.

Pig (Porcine) Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) interaction partners

  1. CD39 and CD73 and their enzymatic activities that convert extracellular nucleotides are highly expressed and could have special function in the valve

Profil protéine Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1)

Profil protéine

Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside ATPases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides.

Gene names and symbols associated with ENTPD1

  • ectonucleoside triphosphate diphosphohydrolase 8 (ENTPD8)
  • ectonucleoside triphosphate diphosphohydrolase 1 L homeolog (entpd1.L)
  • ectonucleoside triphosphate diphosphohydrolase 1 (entpd1)
  • ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1)
  • ectonucleoside triphosphate diphosphohydrolase 1 (Entpd1)
  • 2610206B08Rik Protéine
  • AA408691 Protéine
  • ATPDase Protéine
  • Cd39 Protéine
  • entpd1 Protéine
  • MGC79567 Protéine
  • MGC80631 Protéine
  • NTPDase-1 Protéine
  • zgc:100819 Protéine

Protein level used designations for ENTPD1

E-NTPDase 8 , NTPDase 8 , NTPDase8 , ectonucleoside triphosphate diphosphohydrolase 1 , liver ecto-ATP diphosphohydrolase , NTPDase1 , CD39 antigen , NTPDase 1 , ecto-ATP diphosphohydrolase 1 , ecto-ATPDase 1 , ecto-ATPase 1 , ecto-apyrase , lymphoid cell activation antigen , ectoapyrase , ATPDase , ATP-diphosphohydrolase

GENE ID SPECIES
374095 Gallus gallus
444164 Xenopus laevis
445151 Danio rerio
448501 Xenopus (Silurana) tropicalis
953 Homo sapiens
12495 Mus musculus
64519 Rattus norvegicus
282223 Bos taurus
397298 Sus scrofa
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