Embryonic Ectoderm Development (EED) Kits ELISA

EED encodes a member of the Polycomb-group (PcG) family. De plus, nous expédions Embryonic Ectoderm Development Anticorps (99) et Embryonic Ectoderm Development Protéines (17) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
EED 8726 O75530
EED 13626 Q921E6
EED 293104  
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Showing 10 out of 31 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Souris 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$630.00
Détails
Humain 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$630.00
Détails
Rat 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$638.00
Détails
Porc 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Poulet 1.875 ng/mL 3.125-200 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Lapin 1.875 ng/mL 3.125-200 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Singe 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Cobaye
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails
Mouton
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails
Chévre
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails

Plus Kits ELISA pour Embryonic Ectoderm Development partenaires d'interaction

Human Embryonic Ectoderm Development (EED) interaction partners

  1. we present a patient with a clinical diagnosis of Weaver syndrome and novel de novo sequence variant in EED. Our observation together with previous reports [2, 3, 5] suggests that EED gene testing is warranted in patients with the overgrowth syndrome features and suspicion of Weaver syndrome with normal results for EZH2 (Montrer EZH2 Kits ELISA) gene sequencing.

  2. Data suggest the polycomb repressive complex 2 subunits EZH2 (Montrer EZH2 Kits ELISA), SUZ12, and EED protein axis as promising therapeutic target for treating sarcoma.

  3. we analyzed eight probands with clinically suspected Weaver syndrome by whole-exome sequencing and identified three mutations: a 25.4-kb deletion partially involving EZH2 and CUL1 ,a missense mutation , and a missense mutation in SUZ12 inherited from her father .In vitro functional analyses demonstrated that the identified EED and SUZ12 missense mutations cause decreased decreased trimethylation of lysine 27 of H3

  4. These findings support that Weaver syndrome is a disorder with locus heterogeneity and can be due to pathogenic variants in either EZH2 (Montrer EZH2 Kits ELISA) or EED. This case highlights the utility of exome sequencing as a clinical diagnostic tool for novel gene discovery as well as the importance of re-examination of exome data as new information about gene-disease associations becomes available.

  5. we have found two unrelated families of different ethnicities, with a similar rare phenotype, both associated with de novo mutations in this member of the PRC2 complex, we are confident that EED is indeed a novel overgrowth gene.

  6. Mutations of SUZ12 and EED are reported to have tumor suppressive functions. (Review)

  7. These results suggest that the SNPs of the EED gene might not be associated with susceptibility to CRC (Montrer CALR Kits ELISA).

  8. An integral role for EED as an epigenetic exchange factor coordinating the activities of PRC1 (Montrer PRC1 Kits ELISA) and 2, is reported.

  9. Data show that overall enhancer of zeste 2 (EZH2), embryonic ectoderm development (EED) and suppressor of zeste 12 homolog (SUZ12) expression in the colorectal cancer (CRC) tissues was significantly increased than in the non-cancerous tissue.

  10. EED, a component of Polycomb repressive complex-2 (PRC2) that catalyzes methylation of lysine 27 of histone H3 (Montrer HIST3H3 Kits ELISA) (H3K27), was involved in epithelial-mesenchymal transition (EMT (Montrer ITK Kits ELISA)) of cancer cells induced by Transforming Growth Factor-beta (TGF-beta).

Mouse (Murine) Embryonic Ectoderm Development (EED) interaction partners

  1. Eed deficiency in chondrocytes causes severe kyphosis and a growth defect with decreased chondrocyte proliferation, accelerated hypertrophic differentiation and cell death with reduced Hif1a (Montrer HIF1A Kits ELISA) expression

  2. The progenitors in Eed mutant mice that were induced to differentiate did not develop into properly formed nephrons. Lhx1 (Montrer LHX1 Kits ELISA), normally expressed in the renal vesicle, was overexpressed in kidneys of Eed mutant mice. Thus, PRC2 has a crucial role in suppressing the expression of genes that maintain the progenitor state, allowing nephron differentiation to proceed.

  3. discovery of differentiation stage-specific and dose-dependent roles of EED in normal hematopoiesis and leukemogenesis

  4. our work provides in vivo evidence that the structural integrity of EED to H3K27me3 propagation is critical, especially for embryonic development and hematopoietic homeostasis, and that its perturbation increases the predisposition to hematologic malignancies

  5. Deletion of Eed but not Ezh2 (Montrer EZH2 Kits ELISA) from embryonic urothelial progenitors caused premature differentiation of Krt5 (Montrer KRT5 Kits ELISA)+ basal cells and ectopic expression of squamous cell markers.

  6. in the skin epithelium, EED, Suz12, and Ezh1 (Montrer EZH1 Kits ELISA)/2 function largely as subunits of the PRC2 complex and have roles in skin development

  7. EED is required for proper erythropoiesis and for formation of hematopoietic progenitor and stem cells, but is dispensable for endothelial lineage commitment and early vascular patterning

  8. Genetic inactivation of Ezh2 (Montrer EZH2 Kits ELISA) or Eed cooperates with NRASQ61K in leukemogenesis.

  9. EED affects the lymphoid versus myeloid decision processes within the lymphomyeloid lineage

  10. Inactivation of Eed impedes MLL-AF9-mediated leukemogenesis through Cdkn2a-dependent and Cdkn2a-independent mechanisms in a murine model.

Embryonic Ectoderm Development (EED) profil antigène

Antigen Summary

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with EED

  • embryonic ectoderm development (eed) anticorps
  • embryonic ectoderm development (EED) anticorps
  • embryonic ectoderm development S homeolog (eed.S) anticorps
  • microRNA 6755 (MIR6755) anticorps
  • embryonic ectoderm development (Eed) anticorps
  • embryonic ectoderm development L homeolog (eed.L) anticorps
  • eed anticorps
  • ENSMUSG00000039373 anticorps
  • HEED anticorps
  • l(7)5Rn anticorps
  • l7Rn5 anticorps
  • lusk anticorps
  • psXEED anticorps
  • WAIT1 anticorps
  • Xeed anticorps
  • Xeed-A anticorps
  • Xeed-B anticorps
  • zgc:112509 anticorps

Protein level used designations for EED

polycomb protein eed , embryonic ectoderm development , WD protein associating with integrin cytoplasmic tails 1 , polycomb protein EED , embryonic ectoderm development protein variant 1 , polycomb protein eed-B , embryonic ectoderm development protein , lethal, Chr 7, Rinchik 5 , polycomb protein eed-A

GENE ID SPECIES
550079 Xenopus (Silurana) tropicalis
703866 Macaca mulatta
100601094 Nomascus leucogenys
8726 Homo sapiens
550463 Danio rerio
398420 Xenopus laevis
426381 Gallus gallus
404183 Bos taurus
13626 Mus musculus
293104 Rattus norvegicus
100344036 Oryctolagus cuniculus
100728793 Cavia porcellus
476779 Canis lupus familiaris
101113712 Ovis aries
734571 Xenopus laevis
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