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Can mediate aggregation most likely through a homophilic molecular interaction (By similarity).. De plus, nous expédions ESAM Anticorps (139) et ESAM Protéines (29) et beaucoup plus de produits pour cette protéine.
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Human ESAM Kit ELISA pour Sandwich ELISA - ABIN420161
Hara, Ishida, Cangara, Hirata: Endothelial cell-selective adhesion molecule regulates albuminuria in diabetic nephropathy. dans Microvascular research 2009
Show all 3 Pubmed References
VE-cadherin (Montrer CDH5 Kits ELISA) and Esama have distinct and redundant functions during blood vessel morphogenesis
ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias
Serum ESAM is higher in type 2 diabetes mellitus than in controls and parallels oxidative stress.
ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules.
ESAM expression in hematopoietic progenitors is essential for erythroid recovery after a bone marrow injury.
Runx3 (Montrer RUNX3 Kits ELISA) is required for cell identity, homeostasis and function of splenic Esam(high) dendritic cells.
ESAM levels clearly mirror the shift of hematopoietic stem cells (HSC) between quiescence and activation, and the intensity of expression is prominent in comparison with other HSC-related antigens.
ESAM inactivation can reduce susceptibility to atherosclerosis by inhibiting plaque neovascularization and macrophage infiltration into the atheroma.
findings support a model in which ESAM localizes to platelet contacts following platelet activation in order to limit thrombus growth and stability
ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth
The direct interaction between ESAM and MAGI-1 was confirmed by pull-down experiments. The two proteins formed stable complexes in transfected CHO (Montrer COL11A1 Kits ELISA) cells.
At endothelial tight junctions ESAM participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts.
ESAM marks hematopoietic stem cells in murine fetal liver and will facilitate studies of hematopoiesis throughout life.
Can mediate aggregation most likely through a homophilic molecular interaction (By similarity).
endothelial cell adhesion molecule
, endothelial cell-selective adhesion molecule
, endothelial cell-specific adhesion molecule
, HUEL (C4orf1)-interacting protein
, LP4791 protein