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Transcriptional activator that binds to the enhancer of the adenovirus E1A gene\; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.. De plus, nous expédions ETV4 Protéines (5) et ETV4 Kits (1) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 75 products:
Cow (Bovine) Polyclonal ETV4 Primary Antibody pour WB - ABIN2779533
Span, Manders, Heuvel, Beex, Sweep: E1AF expression levels are not associated with prognosis in human breast cancer. dans Breast cancer research and treatment 2003
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Human Monoclonal ETV4 Primary Antibody pour ELISA, WB - ABIN969121
Zhu, Jiang, Shen, Wang, Zong, Li, Yang, Niu, Liu, Chen, Hu, Gu: Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator. dans The Journal of biological chemistry 2005
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Human Monoclonal ETV4 Primary Antibody pour ELISA, WB - ABIN560805
Han, Mehra, Dhanasekaran, Yu, Menon, Lonigro, Wang, Gong, Wang, Shankar, Laxman, Shah, Varambally, Palanisamy, Tomlins, Kumar-Sinha, Chinnaiyan: A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer. dans Cancer research 2008
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Human Polyclonal ETV4 Primary Antibody pour ICC, IF - ABIN4344677
Wollenick, Hu, Kristiansen, Schraml, Rehrauer, Berchner-Pfannschmidt, Fandrey, Wenger, Stiehl: Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling. dans Nucleic acids research 2012
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four oncogenic ETS (Montrer ETS1 Anticorps) (ERG (Montrer ERG Anticorps), ETV1 (Montrer ETV1 Anticorps), ETV4, and ETV5 (Montrer ETV5 Anticorps)), and no other ETS (Montrer ETS1 Anticorps), interact with the Ewing's sarcoma breakpoint protein, EWS (Montrer EWSR1 Anticorps).
FOS strongly binds to the same MED25 (Montrer MED9 Anticorps) site as ETV4 activation domain and JUN (Montrer JUN Anticorps) interacts with the other two MED25 (Montrer MED9 Anticorps) sites.
Our results indicate that assessing AP1 (Montrer FOSB Anticorps) and PEA3 transcription factor status might be a good indicator of OAC status. However, we could not detect any associations with disease stage or patient treatment regime. This suggests that the PEA3-AP1 (Montrer FOSB Anticorps) regulatory module more likely contributes more generally to the cancer phenotype. In keeping with this observation, depletion of ETV1 (Montrer ETV1 Anticorps) and/or ETV4 causes an OAC cell growth defect
ETV4 overexpression is associated with lung cancer metastasis.
Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETV1 (Montrer ETV1 Anticorps), ETV4 and ETV5 (Montrer ETV5 Anticorps).
The data provide the molecular details of ETV4-mediated NANOG gene expression.
the prostate cancer-related oncogenic E26 transformation-specific (ETS (Montrer ETS1 Anticorps)) transcription factors, ETV1 (Montrer ETV1 Anticorps), ETV4, and ETV5 (Montrer ETV5 Anticorps), were required for TAZ (Montrer TAZ Anticorps) gene transcription in PC3 (Montrer PCSK1 Anticorps) prostate cancer cells
NCOA2ETV4 protein would contain the helixloophelix, PAS_9 and PAS_11, CITED domains, the SRC1 (Montrer SRC Anticorps) domain of NCOA2 (Montrer NCOA2 Anticorps) and the ETS (Montrer ETS1 Anticorps) DNAbinding domain of ETV4.
PEA3-subgroup transcription factors are key players of the Met signaling integration involved in regulation of migration and invasiveness of tumor cells.
ACC1 (Montrer ACACA Anticorps) and ACLY (Montrer ACLY Anticorps) regulate the levels of ETV4 under hypoxia via increased alpha-ketoglutarate. These results reveal that the ACC1 (Montrer ACACA Anticorps)/ACLY (Montrer ACLY Anticorps)-alpha-ketoglutarate-ETV4 axis is a novel means by which metabolic states regulate transcriptional output
Our results will help understand the mechanism of ETV4 overexpression in CRC (Montrer SCRIB Anticorps) patients and provide a clue to search new therapeutic target to treat the related tumors in clinical practice.
ETS-related transcription factors ETV4 and ETV5 (Montrer ETV5 Anticorps) are involved in proliferation and induction of differentiation-associated genes in embryonic stem (ES) cells.
paracrine signaling via fibroblast growth factor 2 (Fgf2 (Montrer FGF2 Anticorps)) and Mapk (Montrer MAPK1 Anticorps) between these diverged tumor subclones causes enhanced expression of the Pea3 transcription factor, resulting in metastatic dissemination of the neuroendocrine tumor subclones.
Study hypothesized that PEA3 might play an essential role in the activation of the FAK (Montrer PTK2 Anticorps) gene during tumor metastasis.
Study reveals molecular insight into how the Ets (Montrer ETS1 Anticorps) family transcription factor Pea3 favors EMT (Montrer ITK Anticorps) and contributes to tumorigenesis via a negative regulatory loop with Cyclin D2 (Montrer CCND2 Anticorps), a new Pea3 target gene.
oncogenic Etv4 promotes prostate cancer metastasis in response to coactivation of PI3-kinase and Ras signaling pathways in a genetically engineered model of highly penetrant, metastatic prostate cancer
PEA3-null fibroblasts exhibit impaired c-src activation and motility defects.
Smad2 (Montrer SMAD2 Anticorps) and PEA3 regulate RGC-32 (Montrer C13orf15 Anticorps) transcription which is essential for smooth muscle cell differentiation from neural crest cells.
study provides evidence for a protumorigenic role of PEA3 factors in breast neoplasia, and supports targeting the PEA3 transcription factor family in breast cancer
Induction of Pea3 gene expression by peripheral signals is required to coordinate the central position and terminal arborization of specific sets of spinal motor neurons.
etv5a (Montrer ETV5 Anticorps) and etv4 have roles in mediating epithelial cell fate during zebrafish kidney development
Pea3 and erm (Montrer ETV5 Anticorps) are required for zebrafish pronephrogenesis and can functionally complement each other, and the wt1a gene may be one of their downstream targets.
Overlapping functions of pea3 ETS (Montrer ETS1 Anticorps) transcription factors in FGF signaling during zebrafish development are reported.
Transcriptional activator that binds to the enhancer of the adenovirus E1A gene\; the core-binding sequence is 5'GT-3'.
ETS translocation variant 4
, EWS protein/E1A enhancer binding protein chimera
, adenovirus E1A enhancer-binding protein
, ets variant gene 4 (E1A enhancer-binding protein, E1AF)
, polyomavirus enhancer activator 3 homolog
, ets variant gene 4 (E1A enhancer binding protein, E1AF)
, polyomavirus enhancer activator-3
, ets domain protein
, ETS variant protein 4
, POLYOMAVIRUS ENHANCER ACTIVATOR 3 (PEA3 PROTEIN) (ETS TRANSLOCATION VARIANT 4)
, ETS translocation variant 4-like
, ETS domain-containing transcription factor PEA3
, ETS-domain transcription factor pea3