Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
The product of EYS contains multiple epidermal growth factor (EGF)-like and LamG domains. De plus, nous expédions et beaucoup plus de produits pour cette protéine.
Showing 4 out of 5 products:
Human Polyclonal EYS Primary Antibody pour ICC, IF - ABIN4309818
Yu, Liu, Li, Natale, Cao, Wang, Amack, Hu: Eyes shut homolog is required for maintaining the ciliary pocket and survival of photoreceptors in zebrafish. dans Biology open 2016
A novel single base pair insertion mutation has been found in the EYS gene in a six generations family with retinitis pigmentosa.
Taken together, with the targeted NGS approach, we reveal novel EYS mutations and prove the efficiency of targeted NGS in the genetic diagnoses of retinitis pigmentosa.
Bietti crystalline dystrophy patients with CYP4V2 (Montrer CYP4V2 Anticorps) mutations showed more severe macular choroid atrophy as compared to EYS-related RP patients. These different damage patterns suggest differences in choroidal expression between CYP4V2 (Montrer CYP4V2 Anticorps) and EYS.
The results obtained in this study lead us to speculate that, in photoreceptor cells, EYS could be a protein involved in maintaining the stability of the ciliary axoneme in both rods and cones. The variability of its isoform structure suggests that other roles are also possible and yet to be established
our study expands the genotypic spectrums for EYS mutations, and may provide novel insights into the relevant pathogenesis for RP. We also demonstrate targeted next-generation sequencing approach as a valuable tool for genetic diagnosis.
New variants were found to be located on the USH2A (Montrer USH2A Anticorps), RPGR (Montrer RPGR Anticorps), EYS, and RHO genes
Advanced retinal degenerative changes with near-total absence of rods and preservation of some perifoveal cones are observed in arRP donor retinas with EYS mutations.
We confirmed with our previous findings that PTP4A1 (Montrer PTP4A1 Anticorps)-PHF3-EYS variants were significantly associated with alcohol dependence.
Our results demonstrated that EYS mutations can be the cause of not only autosomal recessive retinitis pigmentosa but also autoisomal recessive cone-rod dystrophy.
PTP4A1 (Montrer PTP4A1 Anticorps)-PHF3-EYS variants were associated with alcohol dependence.
The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene.
EGF-like-domain, multiple 10
, EGF-like-domain, multiple 11
, epidermal growth factor-like protein 10
, epidermal growth factor-like protein 11
, protein eyes shut homolog
, protein spacemaker homolog