anti-Eyes Shut Homolog (Drosophila) (EYS) Anticorps

The product of EYS contains multiple epidermal growth factor (EGF)-like and LamG domains. De plus, nous expédions et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
EYS 346007 Q5T1H1
EYS    
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Top anti-EYS Anticorps sur anticorps-enligne.fr

Showing 4 out of 5 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunohistochemistry: EYS/RP25 Antibody [NBP1-90038] - Staining of human lung shows moderate cytoplasmic positivity in lung macrophages. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Souris Inconjugué ELISA, WB Detection limit for recombinant GST tagged EYS is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.63 KDa) . 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Souris Inconjugué ELISA, WB EYS polyclonal antibody (A01), Lot # 051205JC01 Western Blot analysis of EYS expression in HeLa . Western Blot detection against Immunogen (37 KDa) . 50 μL Connectez-vous pour afficher 11 to 12 Days
$305.71
Détails
Humain Souris Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 11 to 14 Days
$837.83
Détails

anti-EYS Anticorps mieux référencés

  1. Human Polyclonal EYS Primary Antibody pour ICC, IF - ABIN4309818 : Yu, Liu, Li, Natale, Cao, Wang, Amack, Hu: Eyes shut homolog is required for maintaining the ciliary pocket and survival of photoreceptors in zebrafish. dans Biology open 2016 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre EYS partenaires d’interaction

Human Eyes Shut Homolog (Drosophila) (EYS) interaction partners

  1. The manner of decay of genetically defective EYS gene transcripts in photoreceptor-directed fibroblasts derived from retinitis pigmentosa patients depends on the type of mutation.

  2. Of the 297 unique EYS variants identified, almost half (n = 130) are predicted to result in premature truncation of the EYS protein.

  3. A novel single base pair insertion mutation has been found in the EYS gene in a six generations family with retinitis pigmentosa.

  4. Taken together, with the targeted NGS approach, we reveal novel EYS mutations and prove the efficiency of targeted NGS in the genetic diagnoses of retinitis pigmentosa.

  5. Bietti crystalline dystrophy patients with CYP4V2 mutations showed more severe macular choroid atrophy as compared to EYS-related RP patients. These different damage patterns suggest differences in choroidal expression between CYP4V2 and EYS.

  6. The results obtained in this study lead us to speculate that, in photoreceptor cells, EYS could be a protein involved in maintaining the stability of the ciliary axoneme in both rods and cones. The variability of its isoform structure suggests that other roles are also possible and yet to be established

  7. our study expands the genotypic spectrums for EYS mutations, and may provide novel insights into the relevant pathogenesis for RP. We also demonstrate targeted next-generation sequencing approach as a valuable tool for genetic diagnosis.

  8. New variants were found to be located on the USH2A, RPGR, EYS, and RHO genes

  9. Advanced retinal degenerative changes with near-total absence of rods and preservation of some perifoveal cones are observed in arRP donor retinas with EYS mutations.

  10. We confirmed with our previous findings that PTP4A1-PHF3-EYS variants were significantly associated with alcohol dependence.

  11. It appears that patients share a relatively uniform phenotype with near-normal central visual function up to their twenties. The patients homozygous for the c.4957_4958insA mutation showed a uniform course of visual acuity changes.

  12. Our results demonstrated that EYS mutations can be the cause of not only autosomal recessive retinitis pigmentosa but also autoisomal recessive cone-rod dystrophy.

  13. PTP4A1-PHF3-EYS variants were associated with alcohol dependence.

  14. This study was conducted to determine the spectrum and frequency of EYS mutations in 100 Japanese autosomal recessive retinitis pigmentosa patients.

  15. One-third of Japanese patients with nonsyndromic autosomal recessive retinitis pigmentosa carried probable pathogenic mutations in the EYS gene, including two founder mutations

  16. The results of this GWAS, replication, and fine mapping study provide the first reported evidence that genetic variants mutation within the EYS gene, may be associated with severe statin myopathy.

  17. Results suggest that midsized genomic rearrangements in EYS gene would be a common event in the appearance of retinitis pigmentosa phenotype

  18. The mutations p.D2767Y and p.D3028Y described in this study affect highly conserved residues at homologous positions in laminin A G-like domains and support the notion that missense mutations in EYS can cause autosomal recessive retinitis pigmentosa.

  19. Report the identification of 73 sequence variations in EYS, of which 28 are novel. Of these, 42.9% (12/28) are very likely pathogenic, 17.9% (5/28)are possibly pathogenic, whereas 39.3% (11/28) are SNPs.

  20. EYS is currently the most commonly mutated autosomal recessive retinitis pigmentosa gene in the Israeli population, mainly due to founder mutations

EYS profil antigène

Profil protéine

The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with EYS

  • eyes shut homolog (Drosophila) (EYS) anticorps
  • bA74E24.1 anticorps
  • bA166P24.2 anticorps
  • bA307F22.3 anticorps
  • C6orf178 anticorps
  • C6orf179 anticorps
  • C6orf180 anticorps
  • dJ22I17.2 anticorps
  • dJ303F19.1 anticorps
  • dJ1018A4.2 anticorps
  • EGFL10 anticorps
  • EGFL11 anticorps
  • RP25 anticorps
  • SPAM anticorps

Protein level used designations for EYS

EGF-like-domain, multiple 10 , EGF-like-domain, multiple 11 , epidermal growth factor-like protein 10 , epidermal growth factor-like protein 11 , protein eyes shut homolog , protein spacemaker homolog

GENE ID SPECIES
346007 Homo sapiens
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