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Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif. De plus, nous expédions F-Box Protein 15 Anticorps (62) et F-Box Protein 15 Kits (13) et beaucoup plus de produits pour cette protéine.
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These data suggest that FBXO15 and Ube2r1 regulate P-gp expression through the ubiquitin-proteasome pathway.
TDH, responsible for mitochondrial production of acetyl-CoA in mouse embryonic stem cells, and the acetyltransferase GCN5L1 cooperate to acetylate Lys501 in KBP, allowing its recognition by and degradation via Fbxo15, an F-box protein transcriptionally controlled by the pluripotency core factors and repressed following differentiation.
Fbxo15 mediates degradation of cardiolipin synthase1 in pneumonia.
Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal, development, and fertility.
Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box protein 15
, F-box only protein 15
, f-box only protein 15-like