F-Box Protein 2 Protéines (FBXO2)

FBXO2 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. De plus, nous expédions F-Box Protein 2 Anticorps (64) et F-Box Protein 2 Kits (39) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
FBXO2 26232 Q9UK22
FBXO2 230904 Q80UW2
Rat FBXO2 FBXO2 85273  
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Top F-Box Protein 2 Protéines sur anticorps-enligne.fr

Showing 7 out of 8 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Escherichia coli (E. coli) Humain His tag 50 μg Connectez-vous pour afficher 13 to 16 Days
$400.00
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Escherichia coli (E. coli) Humain His tag,GST tag   50 μg Connectez-vous pour afficher 15 to 18 Days
$450.00
Détails
Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,786.67
Détails

FBXO2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, , ,
Mouse (Murine)

Plus protéines pour F-Box Protein 2 (FBXO2) partenaires d'interaction

Human F-Box Protein 2 (FBXO2) interaction partners

  1. These results suggest that the FBXO2 variant rs9614 C allele may decrease the Parkinson Disease risk in mainland Han Chinese and may be a biomarker for PD.

  2. summary, our findings suggest that FBXO2-regulated EMT (Montrer ITK Protéines) led to carcinogenicity in gastric cancer and may be a novel target in the diagnosis and treatment of gastric cancer.

  3. Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase has been presented.

  4. This study provides new knowledge of the CFTR (Montrer CFTR Protéines) biosynthetic pathway. It suggests that SYVN1 (Montrer SYVN1 Protéines) and FBXO2 represent two distinct multiprotein complexes that may degrade DeltaF508-CFTR (Montrer CFTR Protéines) in airway epithelia and identifies a new role for NEDD8 (Montrer NEDD8 Protéines) in regulating DeltaF508-CFTR (Montrer CFTR Protéines) ubiquitination.

  5. Although the overall structure of FBG3 (Montrer FBXO44 Protéines) is similar to that of Fbs1, the residues that form the Fbs1 carbohydrate-binding pocket failed to be superposed with the corresponding residues of FBG3 (Montrer FBXO44 Protéines).

  6. FBG1 degrades A1AT (Montrer SERPINA1 Protéines)-Z through a Beclin1 (Montrer BECN1 Protéines)-dependent arm of autophagy.

  7. FBG1 is unique among known F-box proteins in that it contains a non-canonical D-Box within F-box domain, required for the growth arrest.

  8. interaction of the HSV-1 UL9 protein with NFB42 results in its polyubiquitination and subsequent degradation by the 26S proteasome (Montrer Psmd4 Protéines)

Mouse (Murine) F-Box Protein 2 (FBXO2) interaction partners

  1. F-box only protein 2 (FBXO2), a substrate recognition component of the Skp1 (Montrer SKP1 Protéines)-Cul1 (Montrer CUL1 Protéines)-F-box protein (Montrer FBXO30 Protéines) (SCF (Montrer KITLG Protéines)) E3 ubiquitin ligase (Montrer MUL1 Protéines) complex, was upregulated in livers of obese mice. Furthermore, using a protein purification approach combined with high-performance liquid chromatography/tandem mass spectrometry, we carried out a system-wide screening of FBXO2 substrates, in which the insulin receptor (IR (Montrer INSR Protéines)) was identified as a substrate

  2. FBG1 degrades A1AT (Montrer SERPINA1 Protéines)-Z through a Beclin1 (Montrer BECN1 Protéines)-dependent arm of autophagy.

  3. The results of this study suggested that Fbxo2 controls the abundance and localization of specific NMDAR (Montrer GRIN1 Protéines) subunits in the brain and may influence synapse formation and maintenance.

  4. these results suggest that Fbxo2 regulates APP (Montrer APP Protéines) levels and processing in the brain and may play a role in modulating Alzheimer disease pathogenesis.

  5. our studies support a non-essential role for FBG1 on the degradation of torsinA (Montrer TOR1A Protéines) and uncover a novel link of FBG1 to the autophagy pathway.

  6. When expressed in hippocampal neurons, the Fbx2 dominant-negative mutant augmented NR1 subunit levels and NMDA receptor-mediated currents in an activity-dependent fashion

  7. Fbs1 assists clearance of aberrant glycoproteins in neuronal cells by suppressing aggregates formation, independent of ubiquitin ligase activity, and thus functions as a unique chaperone for those proteins.

  8. Our findings demonstrate that components of protein quality control are essential for inner ear homeostasis and implicate Fbx2 and Skp1 (Montrer SKP1 Protéines) as potential genetic modifiers in age-related hearing loss.

Profil protéine F-Box Protein 2 (FBXO2)

Profil protéine

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state.

Gene names and symbols associated with F-Box Protein 2 Protéines (FBXO2)

  • F-box protein 2 (FBXO2)
  • F-box protein 2 (Fbxo2)
  • FBG1 Protéine
  • Fbs1 Protéine
  • Fbs2 Protéine
  • FBX2 Protéine
  • NFB42 Protéine
  • OCP1 Protéine
  • Prpl4 Protéine

Protein level used designations for F-Box Protein 2 Protéines (FBXO2)

F-box only protein 2 , F-box gene 1 , organ of Corti protein 1 , prion protein ligand 4 , neural F box protein NFB42

GENE ID SPECIES
457951 Pan troglodytes
26232 Homo sapiens
230904 Mus musculus
85273 Rattus norvegicus
512589 Bos taurus
478231 Canis lupus familiaris
419495 Gallus gallus
101112079 Ovis aries
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